Search Results - "Gann, Peter H"

Metallic air pollutants and breast cancer heterogeneity by Kresovich, Jacob K., Erdal, Serap, Chen, Hua Yun, Gann, Peter H., Argos, Maria, Rauscher, Garth H.

“…Emerging evidence suggests airborne metals may be associated with breast cancer risk. However, breast cancer is heterogenous and associations with heavy metals…”
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Evidence for field cancerization of the prostate by Nonn, Larisa, Ananthanarayanan, Vijayalakshmi, Gann, Peter H.

“…BACKGROUND Field cancerization, which is not yet well‐characterized in the prostate, occurs when large areas of an organ or tissue surface are affected by a…”
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Role of Diet in Prostate Cancer Development and Progression by CHAN, June M, GANN, Peter H, GIOVANNUCCI, Edward L

“…Increasing evidence supports the important role of nutrition in cancer prevention, including prevention of prostate cancer. In this review, we summarize data…”
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Quantification of intrinsic subtype ambiguity in Luminal A breast cancer and its relationship to clinical outcomes by Kumar, Neeraj, Zhao, Dan, Bhaumik, Dulal, Sethi, Amit, Gann, Peter H

“…PAM50 gene profiling assigns each cancer to a single intrinsic subtype. However, individual cancers vary in their adherence to a prototype, and due to bulk…”
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What Is the True Number Needed to Screen and Treat to Save a Life With Prostate-Specific Antigen Testing? by LOEB, Stacy, VONESH, Edward F, METTER, E. Jeffrey, CARTER, H. Ballentine, GANN, Peter H, CATALONA, William J

“…The European Randomized Study of Screening for Prostate Cancer (ERSPC) reported a 20% mortality reduction with prostate-specific antigen (PSA) screening…”
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BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays by Mahmoud, Abeer M, Macias, Virgilia, Al-Alem, Umaima, Deaton, Ryan J, Kadjaksy-Balla, Andre, Gann, Peter H, Rauscher, Garth H

“…Mutations in BRCA1 are associated with familial as well as sporadic aggressive subtypes of breast cancer, but less is known about whether BRCA1 expression or…”
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Empirical comparison of color normalization methods for epithelial-stromal classification in H and E images by Sethi, Amit, Sha, Lingdao, Vahadane, Abhishek Ramnath, Deaton, Ryan J., Kumar, Neeraj, Macias, Virgilia, Gann, Peter H.

“…Context: Color normalization techniques for histology have not been empirically tested for their utility for computational pathology pipelines. Aims: We…”
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Evidence that selenium binding protein 1 is a tumor suppressor in prostate cancer by Ansong, Emmanuel, Ying, Qi, Ekoue, Dede N, Deaton, Ryan, Hall, Andrew R, Kajdacsy-Balla, Andre, Yang, Wancai, Gann, Peter H, Diamond, Alan M

“…Selenium-Binding Protein 1 (SBP1, SELENBP1, hSP56) is a selenium-associated protein shown to be at lower levels in tumors, and its lower levels are frequently…”
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Risk Factors for Prostate Cancer Detection After a Negative Biopsy: A Novel Multivariable Longitudinal Approach by Gann, Peter H, Fought, Angela, Deaton, Ryan, Catalona, William J, Vonesh, Edward

“…To introduce a novel approach for the time-dependent quantification of risk factors for prostate cancer (PCa) detection after an initial negative biopsy. Data…”
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Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury by Moreno-Vinasco, Liliana, Quijada, Hector, Sammani, Saad, Siegler, Jessica, Letsiou, Eleftheria, Deaton, Ryan, Saadat, Laleh, Zaidi, Rafe S, Messana, Joe, Gann, Peter H, Machado, Roberto F, Ma, Wenli, Camp, Sara M, Wang, Ting, Garcia, Joe G N

“…We previously identified the intracellular nicotinamide phosphoribosyltransferase (iNAMPT, aka pre-B-cell colony enhancing factor) as a candidate gene…”
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Gene expression patterns in the human breast after pregnancy by Asztalos, Szilard, Gann, Peter H, Hayes, Meghan K, Nonn, Larisa, Beam, Craig A, Dai, Yang, Wiley, Elizabeth L, Tonetti, Debra A

“…Epidemiologic studies have established that pregnancy has a bidirectional, time-dependent effect on breast cancer risk; a period of elevated risk is followed…”
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Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer by Kataria, Yachana, Deaton, Ryan J, Enk, Erika, Jin, Ming, Petrauskaite, Milita, Dong, Linlin, Goldenberg, Joseph R, Cotler, Scott J, Jensen, Donald M, van Breemen, Richard B, Gann, Peter H

“…Approximately 2.7 million Americans are chronically infected with hepatitis C virus (HCV). HCV patients with cirrhosis form the largest group of persons at…”
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Prostate‐derived circulating microRNAs add prognostic value to prostate cancer risk calculators by Zenner, Morgan L., Kirkpatrick, Brenna, Leonardo, Trevor R., Schlicht, Michael J., Saldana, Alejandra Cavazos, Loitz, Candice, Valyi‐Nagy, Klara, Maienschein‐Cline, Mark, Gann, Peter H., Abern, Michael, Nonn, Larisa

“…Prostate cancer is the second leading cause of malignancy‐related deaths among American men. Active surveillance is a safe option for many men with less…”
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Development of a nuclear morphometric signature for prostate cancer risk in negative biopsies by Gann, Peter H, Deaton, Ryan, Amatya, Anup, Mohnani, Mahesh, Rueter, Erika Enk, Yang, Yirong, Ananthanarayanan, Viju

“…Our objective was to develop and validate a multi-feature nuclear score based on image analysis of direct DNA staining, and to test its association with field…”
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Impact of genomic testing on urologists' treatment preference in favorable risk prostate cancer: A randomized trial by Carbunaru, Samuel, Sun, Zequn, McCall, Cordero, Ofori, Bernice, Marshall, Norma, Wang, Heidy, Abern, Michael, Liu, Li, Hollowell, Courtney M. P., Sharifi, Roohollah, Vidal, Patricia, Kajdacsy‐Balla, Andre, Sekosan, Marin, Ferrer, Karen, Wu, Shoujin, Gallegos, Marlene, Gann, Peter H., Moreira, Daniel, Sharp, Lisa K., Ferrans, Carol E., Murphy, Adam B.

“…Introduction The Oncotype Dx Genomic Prostate Score (GPS) is a 17‐gene relative expression assay that predicts adverse pathology at prostatectomy. We conducted…”
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Deep Learning to Estimate Human Epidermal Growth Factor Receptor 2 Status from Hematoxylin and Eosin-Stained Breast Tissue Images by Anand, Deepak, Kurian, Nikhil Cherian, Dhage, Shubham, Kumar, Neeraj, Rane, Swapnil, Gann, Peter H., Sethi, Amit

“…Context: Several therapeutically important mutations in cancers are economically detected using immunohistochemistry (IHC), which highlights the overexpression…”
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Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study by Chan, June M., Stampfer, Meir J., Giovannucci, Edward, Gann, Peter H., Ma, Jing, Wilkinson, Peter, Hennekens, Charles H., Pollak, Michael

“…Insulin-like growth factor-I (IGF-I) is a mitogen for prostate epithelial cells. To investigate associations between plasma IGF levels and prostate cancer…”
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mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: Valuable tool for risk assessment and prevention trials by Nonn, Larisa, Vaishnav, Avani, Gallagher, Lindsay, Gann, Peter H.

“…Diagnosis of prostate cancer (PCa) typically relies on needle biopsies, which are routinely archived in paraffin after formalin fixation and may contain…”
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Weakly supervised learning on unannotated H&E‐stained slides predicts BRAF mutation in thyroid cancer with high accuracy by Anand, Deepak, Yashashwi, Kumar, Kumar, Neeraj, Rane, Swapnil, Gann, Peter H, Sethi, Amit

“…Deep neural networks (DNNs) that predict mutational status from H&E slides of cancers can enable inexpensive and timely precision oncology. Although expert…”
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Colorectal Cancer Mortality and Factors Related to the Insulin Resistance Syndrome by Colangelo, Laura A, Gapstur, Susan M, Gann, Peter H, Dyer, Alan R, Liu, Kiang

“…It has been proposed that hyperinsulinemia is involved in colon carcinogenesis. An association between post-load plasma glucose (PLG) levels and risk of…”
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