Search Results - "Ganini, Douglas"

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis by Chatterjee, Saurabh, Ganini, Douglas, Tokar, Erik J, Kumar, Ashutosh, Das, Suvarthi, Corbett, Jean, Kadiiska, Maria B, Waalkes, Michael P, Diehl, Anna Mae, Mason, Ronald P

“…Background & Aims Progression from steatosis to steatohepatitic lesions is hypothesized to require a second hit. These lesions have been associated with…”
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Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells by Ganini, Douglas, Leinisch, Fabian, Kumar, Ashutosh, Jiang, JinJie, Tokar, Erik J, Malone, Christine C, Petrovich, Robert M, Mason, Ronald P

“…Fluorescent proteins are an important tool that has become omnipresent in life sciences research. They are frequently used for localization of proteins and…”
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Absence of an effect of vitamin E on protein and lipid radical formation during lipoperoxidation of LDL by lipoxygenase by Ganini, Douglas, Mason, Ronald P

“…Low-density lipoprotein (LDL) oxidation is the primary event in atherosclerosis, and LDL lipoperoxidation leads to modifications in apolipoprotein B-100 (apo…”
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The peroxidase activity of mitochondrial superoxide dismutase by Ansenberger-Fricano, Kristine, Ganini, Douglas, Mao, Mao, Chatterjee, Saurabh, Dallas, Shannon, Mason, Ronald P., Stadler, Krisztian, Santos, Janine H., Bonini, Marcelo G.

“…Manganese superoxide dismutase (MnSOD) is an integral mitochondrial protein known as a first-line antioxidant defense against superoxide radical anions…”
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Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression by Lozoya, Oswaldo A, Wang, Tianyuan, Grenet, Dagoberto, Wolfgang, Taylor C, Sobhany, Mack, Ganini da Silva, Douglas, Riadi, Gonzalo, Chandel, Navdeep, Woychik, Richard P, Santos, Janine H

“…The impact of mitochondrial dysfunction in epigenetics is emerging, but our understanding of this relationship and its effect on gene expression remains…”
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Astaxanthin supplementation delays physical exhaustion and prevents redox imbalances in plasma and soleus muscles of Wistar rats by Polotow, Tatiana G, Vardaris, Cristina V, Mihaliuc, Andrea R, Gonçalves, Marina S, Pereira, Benedito, Ganini, Douglas, Barros, Marcelo P

“…Astaxanthin (ASTA) is a pinkish-orange carotenoid commonly found in marine organisms, especially salmon. ASTA is a powerful antioxidant and suggested to…”
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Redox Status and Neuro Inflammation Indexes in Cerebellum and Motor Cortex of Wistar Rats Supplemented with Natural Sources of Omega-3 Fatty Acids and Astaxanthin: Fish Oil, Krill Oil, and Algal Biomass by Polotow, Tatiana G, Poppe, Sandra C, Vardaris, Cristina V, Ganini, Douglas, Guariroba, Maísa, Mattei, Rita, Hatanaka, Elaine, Martins, Maria F, Bondan, Eduardo F, Barros, Marcelo P

“…Health authorities worldwide have consistently recommended the regular consumption of marine fishes and seafood to preserve memory, sustain cognitive…”
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Effects of acute creatine supplementation on iron homeostasis and uric acid-based antioxidant capacity of plasma after wingate test by Barros, Marcelo P, Ganini, Douglas, Lorenço-Lima, Leandro, Soares, Chrislaine O, Pereira, Benedito, Bechara, Etelvino Jh, Silveira, Leonardo R, Curi, Rui, Souza-Junior, Tacito P

“…Dietary creatine has been largely used as an ergogenic aid to improve strength and athletic performance, especially in short-term and high energy-demanding…”
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Immuno-spin trapping of macromolecules free radicals in vitro and in vivo – One stop shopping for free radical detection by Mason, Ronald P., Ganini, Douglas

“…The only general technique that allows the unambiguous detection of free radicals is electron spin resonance (ESR). However, ESR spin trapping has severe…”
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Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson's disease by Kumar, Ashutosh, Ganini, Douglas, Mason, Ronald P

“…The pathological features of Parkinson's disease (PD) include an abnormal accumulation of α-synuclein in the surviving dopaminergic neurons. Though PD is…”
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Role of cytochrome c in [alpha]-synuclein radical formation: implications of [alpha]-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson's disease by Kumar, Ashutosh, Ganini, Douglas, Mason, Ronald P

“…Background The pathological features of Parkinson's disease (PD) include an abnormal accumulation of [alpha]-synuclein in the surviving dopaminergic neurons…”
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KO of 5-InsP₇ kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype by Gu, Chunfang, Nguyen, Hoai-Nghia, Ganini, Douglas, Chen, Zhaowei, Jessen, Henning J., Gu, Zhen, Wang, Huanchen, Shears, Stephen B.

“…The inositol pyrophosphates 5-InsP₇ (diphosphoinositol pentakisphosphate) and 1,5-InsP₈ (bis-diphosphoinositol tetrakisphosphate) are highly energetic cellular…”
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386 - Cytochrome c as a Peroxidase Plays a Role in Alpha-Synuclein Radical Formation: Implications of Alpha-Synuclein in Alterations of Biological Pathways and Neuronal Death in Maneb- and Paraquat-Induced Model of Parkinson's Disease by Kumar, Ashutosh, Ganini, Douglas, Mason, Ronald

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Cytochrome c as a Peroxidase Plays a Role in Alpha-Synuclein Radical Formation: Implications of Alpha-Synuclein in Alterations of Biological Pathways and Neuronal Death in Maneb- and Paraquat-Induced Model of Parkinson's Disease by Kumar, Ashutosh, Ganini, Douglas, Mason, Ronald

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MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer by Hart, Peter C., Mao, Mao, de Abreu, Andre Luelsdorf P., Ansenberger-Fricano, Kristine, Ekoue, Dede N., Ganini, Douglas, Kajdacsy-Balla, Andre, Diamond, Alan M., Minshall, Richard D., Consolaro, Marcia E. L., Santos, Janine H., Bonini, Marcelo G.

“…Manganese superoxide dismutase (MnSOD/SOD2) is a mitochondria-resident enzyme that governs the types of reactive oxygen species egressing from the organelle to…”
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SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer by He, Chenxia, Danes, Jeanne M., Hart, Peter C., Zhu, Yueming, Huang, Yunping, deAbreu, Andre Luelsdorf, O’Brien, Joseph, Mathison, Angela J., Tang, Binwu, Frasor, Jonna M., Wakefield, Lalage M., Ganini, Douglas, Stauder, Erich, Zielonka, Jacek, Gantner, Benjamin N., Urrutia, Raul A., Gius, David, Bonini, Marcelo G.

“…Mitochondrial superoxide dismutase (SOD2) suppresses tumor initiation but promotes invasion and dissemination of tumor cells at later stages of the disease…”
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Lipoperoxidation with Consequent Protein Radical Formation During LDL Oxidation by Ganini, Douglas, Mason, Ronald P.

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Acetylation activates an alternative function of SOD2 as a stemness factor in breast cancer by Bonini, Marcelo, He, Chenxia, Hart, Peter, Zhu, Yueming, da Silva, Douglas Ganini, Gius, David

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205 - Switch of Mitochondrial Superoxide Dismutase (SOD2) into a Prooxidant Peroxidase in Manganese-deficient Cells and Mice by Ganini, Douglas, Santos, Janine H., Bonini, Marcelo G., Mason, Ronald P.

“…Reactive oxygen species (ROS), in particular the superoxide radical anion O2•‒, are constantly produced during respiration and are increased in many human…”
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Switch of Mitochondrial Superoxide Dismutase (SOD2) into a Prooxidant Peroxidase in Manganese-deficient Cells and Mice by Ganini, Douglas, Santos, Janine H., Bonini, Marcelo G., Mason, Ronald P.

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