Search Results - "Ganguly, Sudakshina"
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Dual DNA binding mode of a turn-on red fluorescent probe thiazole coumarin
Published in PloS one (17-09-2020)“…Turn-on fluorescent probes show enhanced emission upon DNA binding, advocating their importance in imaging cellular DNA. We have probed the DNA binding mode of…”
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Sequence-Specific Dual DNA Binding Modes and Cytotoxicities of N‑6-Functionalized Norcryptotackieine Alkaloids
Published in Journal of natural products (Washington, D.C.) (28-07-2023)“…Norcryptotackieine (1a) belongs to the indoloquinoline class of alkaloids isolated from Cryptolepis sanguinolenta, a plant species that has been traditionally…”
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DNA Minor Groove-Induced cis–trans Isomerization of a Near-Infrared Fluorescent Probe
Published in Biochemistry (Easton) (06-07-2021)“…The discovery of small molecules that exhibit turn-on far-red or near-infrared (NIR) fluorescence upon DNA binding and understanding how they bind DNA are…”
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The Benzyl Moiety in a Quinoxaline-Based Scaffold Acts as a DNA Intercalation Switch
Published in Angewandte Chemie International Edition (27-06-2016)“…Quinoxaline antibiotics intercalate dsDNA and exhibit antitumor properties. However, they are difficult to synthesize and their structural complexity impedes a…”
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EMDB—the Electron Microscopy Data Bank
Published in Nucleic acids research (05-01-2024)“…Abstract The Electron Microscopy Data Bank (EMDB) is the global public archive of three-dimensional electron microscopy (3DEM) maps of biological specimens…”
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Understanding Antisense Oligonucleotide Efficiency in Inhibiting Prokaryotic Gene Expression
Published in ACS infectious diseases (08-03-2024)“…Oligonucleotides offer a unique opportunity for sequence specific regulation of gene expression in bacteria. A fundamental question to address is the choice of…”
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Journal Article -
7
Dual DNA binding mode of a turn-on red fluorescent probe thiazole coumarin
Published in PloS one (01-01-2020)“…Turn-on fluorescent probes show enhanced emission upon DNA binding, advocating their importance in imaging cellular DNA. We have probed the DNA binding mode of…”
Get full text
Journal Article -
8
The Benzyl Moiety in a Quinoxaline-Based Scaffold Acts as a DNA Intercalation Switch
Published in Angewandte Chemie (27-06-2016)“…Quinoxaline antibiotics intercalate dsDNA and exhibit antitumor properties. However, they are difficult to synthesize and their structural complexity impedes a…”
Get full text
Journal Article