Search Results - "Ganguly, Saptadwipa"
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Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity
Published in Frontiers in oncology (29-03-2022)“…Prostate apoptosis response-4 (Par-4) is a tumor suppressor that induces apoptosis in cancer cells. However, the physiological function of Par-4 remains…”
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ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization
Published in Cancers (02-02-2023)“…Melanomas harboring mutations are a particularly aggressive and deadly subtype. If patients cannot tolerate or the melanomas are insensitive to immune…”
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Abstract 1103: Molecular signature for treatment-responsive and recurrent Wilms tumors
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Wilms tumor is the most common solid renal malignancy in children. To better understand the biology of Wilms tumors and develop drugs especially…”
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Crizotinib induces Par-4 secretion from normal cells and GRP78 expression on the cancer cell surface for selective tumor growth inhibition
Published in American journal of cancer research (01-01-2023)“…Lung cancer is the leading cause of cancer-related deaths. Lung cancer cells develop resistance to apoptosis by suppressing the secretion of the tumor…”
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