Search Results - "Ganguly, Karunesh"
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Targeted modulation of neural population dynamics to improve movement control
Published in Brain stimulation (01-01-2023)Get full text
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Competing Roles of Slow Oscillations and Delta Waves in Memory Consolidation versus Forgetting
Published in Cell (03-10-2019)“…Sleep has been implicated in both memory consolidation and forgetting of experiences. However, it is unclear what governs the balance between consolidation and…”
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Sleep-Dependent Reactivation of Ensembles in Motor Cortex Promotes Skill Consolidation
Published in PLoS biology (01-09-2015)“…Despite many prior studies demonstrating offline behavioral gains in motor skills after sleep, the underlying neural mechanisms remain poorly understood. To…”
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Emergence of a stable cortical map for neuroprosthetic control
Published in PLoS biology (21-07-2009)“…Cortical control of neuroprosthetic devices is known to require neuronal adaptations. It remains unclear whether a stable cortical representation for…”
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Emergent modular neural control drives coordinated motor actions
Published in Nature neuroscience (01-07-2019)“…A remarkable feature of motor control is the ability to coordinate movements across distinct body parts into a consistent, skilled action. To reach and grasp…”
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Emergence of task-related spatiotemporal population dynamics in transplanted neurons
Published in Nature communications (11-11-2023)“…Loss of nervous system tissue after severe brain injury is a main determinant of poor functional recovery. Cell transplantation is a promising method to…”
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Neural reactivations during sleep determine network credit assignment
Published in Nature neuroscience (01-09-2017)“…A fundamental goal of learning is to establish neural patterns that cause desired behaviors. This paper demonstrates that sleep-dependent processing is…”
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Plug-and-play control of a brain–computer interface through neural map stabilization
Published in Nature biotechnology (01-03-2021)“…Brain–computer interfaces (BCIs) enable control of assistive devices in individuals with severe motor impairments. A limitation of BCIs that has hindered…”
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Transition from predictable to variable motor cortex and striatal ensemble patterning during behavioral exploration
Published in Nature communications (04-05-2022)“…Animals can capitalize on invariance in the environment by learning and automating highly consistent actions; however, they must also remain flexible and adapt…”
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Coupling between motor cortex and striatum increases during sleep over long-term skill learning
Published in eLife (10-09-2021)“…The strength of cortical connectivity to the striatum influences the balance between behavioral variability and stability. Learning to consistently produce a…”
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Emergence of preparatory dynamics in VIP interneurons during motor learning
Published in Cell reports (Cambridge) (29-08-2023)“…To determine what actions to perform in each context, animals must learn how to execute motor programs in response to sensory cues. In rodents, the interface…”
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Generalizable spelling using a speech neuroprosthesis in an individual with severe limb and vocal paralysis
Published in Nature communications (08-11-2022)“…Neuroprostheses have the potential to restore communication to people who cannot speak or type due to paralysis. However, it is unclear if silent attempts to…”
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Coordinated increase of reliable cortical and striatal ensemble activations during recovery after stroke
Published in Cell reports (Cambridge) (13-07-2021)“…Skilled movements rely on a coordinated cortical and subcortical network, but how this network supports motor recovery after stroke is unknown. Previous…”
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Oscillatory phase coupling coordinates anatomically dispersed functional cell assemblies
Published in Proceedings of the National Academy of Sciences - PNAS (05-10-2010)“…Hebb proposed that neuronal cell assemblies are critical for effective perception, cognition, and action. However, evidence for brain mechanisms that…”
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Selective modulation of cortical population dynamics during neuroprosthetic skill learning
Published in Scientific reports (24-09-2022)“…Brain-machine interfaces (BMIs) provide a framework for studying how cortical population dynamics evolve over learning in a task in which the mapping between…”
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Effects of somatosensory electrical stimulation on motor function and cortical oscillations
Published in Journal of neuroengineering and rehabilitation (13-11-2017)“…Few patients recover full hand dexterity after an acquired brain injury such as stroke. Repetitive somatosensory electrical stimulation (SES) is a promising…”
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Coincident Pre- and Postsynaptic Activity Modifies GABAergic Synapses by Postsynaptic Changes in Cl − Transporter Activity
Published in Neuron (Cambridge, Mass.) (28-08-2003)“…Coincident pre- and postsynaptic activation is known to induce long-term modification of glutamatergic synapses. We report here that, in both hippocampal…”
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Task-dependent changes in cross-level coupling between single neurons and oscillatory activity in multiscale networks
Published in PLoS computational biology (01-12-2012)“…Understanding the principles governing the dynamic coordination of functional brain networks remains an important unmet goal within neuroscience. How do…”
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Cortical neuroprosthetics from a clinical perspective
Published in Neurobiology of disease (01-11-2015)“…Abstract Recent pilot clinical studies have demonstrated that subjects with severe disorders of movement and communication can exert direct neural control over…”
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Large-scale changes in cortical dynamics triggered by repetitive somatosensory electrical stimulation
Published in Journal of neuroengineering and rehabilitation (24-05-2019)“…Repetitive somatosensory electrical stimulation (SES) of forelimb peripheral nerves is a promising therapy; studies have shown that SES can improve motor…”
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