Search Results - "Gangula, R"

Active invasion of oral and aortic tissues by Porphyromonas gingivalis in mice causally links periodontitis and atherosclerosis by Velsko, Irina M, Chukkapalli, Sasanka S, Rivera, Mercedes F, Lee, Ju-Youn, Chen, Hao, Zheng, Donghang, Bhattacharyya, Indraneel, Gangula, Pandu R, Lucas, Alexandra R, Kesavalu, Lakshmyya

“…Atherosclerotic vascular disease is a leading cause of myocardial infarction and cerebrovascular accident, and independent associations with periodontal…”
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Role of oral and gut microbiome in nitric oxide-mediated colon motility by Walker, Miriam Y., Pratap, Siddharth, Southerland, Janet H., Farmer-Dixon, Cherae M., Lakshmyya, Kesavalu, Gangula, Pandu R.

“…Periodontal disease (PD), a severe form of gum disease, is among the most prevalent chronic infection in humans and is associated with complex microbial…”
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Role of sex hormones and their receptors on gastric Nrf2 and neuronal nitric oxide synthase function in an experimental hyperglycemia model by Sprouse, Jeremy, Sampath, Chethan, Gangula, Pandu R

“…Gastroparesis, a condition of abnormal gastric emptying, is most commonly observed in diabetic women. To date, the role of ovarian hormones and/or gastric…”
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Cinnamaldehyde Protects against P. gingivalis Induced Intestinal Epithelial Barrier Dysfunction in IEC-6 Cells via the PI3K/Akt-Mediated NO/Nrf2 Signaling Pathway by Sampath, Chethan, Chukkapalli, Sasanka S, Raju, Abhinav V, Alluri, Leela Subhashini C, Srisai, Dollada, Gangula, Pandu R

“…( ), a Gram-negative oral pathogen, promotes and accelerates periodontitis-associated gut disorders. Intestinal epithelial barrier dysfunction is crucial in…”
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Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice by Sampath, Chethan, Wilus, Derek, Tabatabai, Mohammad, Freeman, Michael L., Gangula, Pandu R.

“…Diabetic gastroparesis (DG) exhibits delayed gastric emptying (GE) due to impaired gastric non-adrenergic, non-cholinergic (NANC) relaxation. These defects are…”
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Invasion of oral and aortic tissues by oral spirochete Treponema denticola in ApoE(-/-) mice causally links periodontal disease and atherosclerosis by Chukkapalli, Sasanka S, Rivera, Mercedes F, Velsko, Irina M, Lee, Ju-Youn, Chen, Hao, Zheng, Donghang, Bhattacharyya, Indraneel, Gangula, Pandu R, Lucas, Alexandra R, Kesavalu, Lakshmyya

“…Treponema denticola is a predominantly subgingival oral spirochete closely associated with periodontal disease and has been detected in atherosclerosis. This…”
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Identification of Specific Oral and Gut Pathogens in Full Thickness Colon of Colitis Patients: Implications for Colon Motility by Dinakaran, Vasudevan, Mandape, Sammed N, Shuba, Kristina, Pratap, Siddharth, Sakhare, Shruti S, Tabatabai, Mohammad Ali, Smoot, Duane T, Farmer-Dixon, Cherae M, Kesavalu, Lakshmyya N, Adunyah, Samuel Evans, Southerland, Janet Hayes, Gangula, Pandu R

“…Impaired colon motility is one of the leading problems associated with inflammatory bowel disease (IBD). An expanding body of evidence supports the role of…”
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Impairment of Gastric Nitrergic and NRF2 System in Apolipoprotein E Knockout Mice by Ravella, Kalpana, Yang, Hong, Gangula, Pandu R. R.

“…Background and Aim Gastric motility dysfunction is most commonly seen in diabetic and idiopathic gastroparesis patients. Recently we reported that impaired…”
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Saliva as a diagnostic tool to measure polycyclic aromatic hydrocarbon exposure in dental patients exposed to intimate partner violence (IPV) by Ramesh, Aramandla, Halpern, Leslie R, Southerland, Janet H, Adunyah, Samuel E, Gangula, Pandu R

“…Social habits such as tobacco use, alcohol consumption, and chemically contaminated diet contribute to poor oral health. Intimate Partner Violence (IPV) is a…”
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Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Markers with an Atheroprotective Immune Response in ApoE(null) Mice by Velsko, Irina M, Chukkapalli, Sasanka S, Rivera-Kweh, Mercedes F, Chen, Hao, Zheng, Donghang, Bhattacharyya, Indraneel, Gangula, Pandu R, Lucas, Alexandra R, Kesavalu, Lakshmyya

“…The American Heart Association supports an association between periodontal disease (PD) and atherosclerotic vascular disease (ASVD) but does not as of yet…”
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Effects of Diabetes on Salivary Gland Protein Expression of Tetrahydrobiopterin and Nitric Oxide Synthesis and Function by Stewart, Cassandra R., Obi, Nneka, Epane, Elodie C., Akbari, Alexander A., Halpern, Leslie, Southerland, Janet H., Gangula, Pandu R.

“…Background: Xerostomia is defined as dry mouth resulting from a change in the amount or composition of saliva and is often a major oral health complication…”
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Gender Bias in Gastroparesis: Is Nitric Oxide the Answer? by Gangula, P. R. R., Sekhar, K. R., Mukhopadhyay, S.

“…Accumulating evidence suggests that gender-related differences are prominent in gastric motility functions in both health and disease. Women are more…”
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SARS-CoV-2 Infection and Oral Health: Therapeutic Opportunities and Challenges by Coke, Christopher J, Davison, Brandon, Fields, Niariah, Fletcher, Jared, Rollings, Joseph, Roberson, Leilani, Challagundla, Kishore B, Sampath, Chethan, Cade, James, Farmer-Dixon, Cherae, Gangula, Pandu R

“…The novel corona virus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and the disease it causes, COVID-19 (Coronavirus Disease-2019) have had…”
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Supplementation of 17β-Estradiol Normalizes Rapid Gastric Emptying by Restoring Impaired Nrf2 and nNOS Function in Obesity-Induced Diabetic Ovariectomized Mice by Sprouse, Jeremy C, Sampath, Chethan, Gangula, Pandu R

“…Gastroparesis (Gp) is a multifactorial condition commonly observed in females and is characterized by delayed or rapid gastric emptying (GE). The role of…”
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Diabetes induces sex-dependent changes in neuronal nitric oxide synthase dimerization and function in the rat gastric antrum by Gangula, Pandu R R, Maner, William L, Micci, Maria-Adelaide, Garfield, Robert E, Pasricha, Pankaj Jay

“…Diabetic gastroparesis is a disorder that predominantly affects women. However, the biological basis of this sex bias remains completely unknown. In this study…”
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Chronic Estrogen Deficiency Causes Gastroparesis by Altering Neuronal Nitric Oxide Synthase Function by Ravella, K., Al-Hendy, A., Sharan, C., Hale, A. B., Channon, K. M., Srinivasan, S., Gangula, P. R.

“…Background Gastroparesis affects predominantly females; however, the biological basis for this gender bias is completely unknown. Several lines of evidence…”
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Adrenomedullin Relaxes Rat Uterine Artery: Mechanisms and Influence of Pregnancy and Estradiol by Ross, Gracious R, Yallampalli, Uma, Gangula, Pandu R. R, Reed, Luckey, Sathishkumar, K, Gao, Haijun, Chauhan, Madhu, Yallampalli, Chandra

“…Uterine arteries play a major role in regulating uteroplacental blood flow. Failure to maintain blood flow to the uteroplacental compartment during pregnancy…”
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Age-related changes in dorsal root ganglia, circulating and vascular calcitonin gene-related peptide (CGRP) concentrations in female rats: Effect of female sex steroid hormones by Gangula, Pandu R.R., Chauhan, Madhu, Reed, Luckey, Yallampalli, Chandra

“…The aim of the present study is to investigate whether immunoreactive (I) calcitonin gene-related peptide (CGRP) content is decreased in plasma and mesenteric…”
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Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2 by WINTER, S. F, ACEVEDO, V. D, GANGULA, R. D, FREEMAN, K. W, SPENCER, D. M, GREENBERG, N. M

“…The expression of fibroblast growth factor receptor (FGFR)-1 correlates with angiogenesis and is associated with prostate cancer (CaP) progression. To more…”
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Inhibitors of advanced glycation end‐products prevent loss of enteric neuronal nitric oxide synthase in diabetic rats by Jeyabal, P. V. S., Kumar, R., Gangula, P. R. R., Micci, M.‐a., Pasricha, P. J.

“…Gastrointestinal dysfunction is common in diabetes, and several studies indicate that loss of neuronal nitrergic inhibition may play an important role in its…”
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