Search Results - "Gangopadhyay, Sumit"

Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications by Gangopadhyay, Sumit, Gore, Kiran R

“…Nucleic acid-based therapeutics that control gene expression have been steadily progressing towards achieving their full clinical potential throughout the last…”
Get full text

Folate Receptor-Mediated siRNA Delivery: Recent Developments and Future Directions for RNAi Therapeutics by Gangopadhyay, Sumit, Nikam, Rahul R, Gore, Kiran R

“…RNA interference (RNAi), a gene regulatory process mediated by small interfering RNAs (siRNAs), has made remarkable progress as a potential therapeutic agent…”
Get more information

4′‑C‑Acetamidomethyl-2′‑O‑methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small Interfering RNAs by Gangopadhyay, Sumit, Das, Gourav, Gupta, Shalini, Ghosh, Atanu, Bagale, Siddharam Shivappa, Roy, Pritam Kumar, Mandal, Mahitosh, Harikrishna, S., Sinha, Surajit, Gore, Kiran R.

“…In this study, we designed the 4′-C-acetamidomethyl-2′-O-methoxyethyl (4′-C-ACM-2′-O-MOE) uridine and thymidine modifications, aiming to test them into small…”
Get full text