Search Results - "Gangal, Himanshu"

Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility by Ma, Tengfei, Huang, Zhenbo, Xie, Xueyi, Cheng, Yifeng, Zhuang, Xiaowen, Childs, Matthew J, Gangal, Himanshu, Wang, Xuehua, Smith, Laura N, Smith, Rachel J, Zhou, Yubin, Wang, Jun

“…Exposure to addictive substances impairs flexible decision making. Cognitive flexibility is mediated by striatal cholinergic interneurons (CINs). However, how…”
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Drug reinforcement impairs cognitive flexibility by inhibiting striatal cholinergic neurons by Gangal, Himanshu, Xie, Xueyi, Huang, Zhenbo, Cheng, Yifeng, Wang, Xuehua, Lu, Jiayi, Zhuang, Xiaowen, Essoh, Amanda, Huang, Yufei, Chen, Ruifeng, Smith, Laura N., Smith, Rachel J., Wang, Jun

“…Addictive substance use impairs cognitive flexibility, with unclear underlying mechanisms. The reinforcement of substance use is mediated by the striatal…”
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A Model of Induction of Cerebellar Long-Term Depression Including RKIP Inactivation of Raf and MEK by Hepburn, Iain, Jain, Anant, Gangal, Himanshu, Yamamoto, Yukio, Tanaka-Yamamoto, Keiko, De Schutter, Erik

“…We report an updated stochastic model of cerebellar Long Term Depression (LTD) with improved realism. Firstly, we verify experimentally that dissociation of…”
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Optogenetic induction of orbitostriatal long-term potentiation in the dorsomedial striatum elicits a persistent reduction of alcohol-seeking behavior in rats by Cheng, Yifeng, Xie, Xueyi, Lu, Jiayi, Gangal, Himanshu, Wang, Wei, Melo, Sebastian, Wang, Xuehua, Jerger, Jared, Woodson, Kayla, Garr, Eric, Huang, Yufei, Janak, Patricia, Wang, Jun

“…Uncontrolled drug-seeking and -taking behaviors are generally driven by maladaptive corticostriatal synaptic plasticity. The orbital frontal cortex (OFC) and…”
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Striatal μ-opioid receptor activation triggers direct-pathway GABAergic plasticity and induces negative affect by Wang, Wei, Xie, Xueyi, Zhuang, Xiaowen, Huang, Yufei, Tan, Tao, Gangal, Himanshu, Huang, Zhenbo, Purvines, William, Wang, Xuehua, Stefanov, Alexander, Chen, Ruifeng, Rodriggs, Lucas, Chaiprasert, Anita, Yu, Emily, Vierkant, Valerie, Hook, Michelle, Huang, Yun, Darcq, Emmanuel, Wang, Jun

“…Withdrawal from chronic opioid use often causes hypodopaminergic states and negative affect, which may drive relapse. Direct-pathway medium spiny neurons…”
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