Search Results - "Ganesh, Kripa"
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1
Quantitative self-assembly prediction yields targeted nanomedicines
Published in Nature materials (01-04-2018)“…Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical…”
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Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Published in Nature communications (20-10-2022)“…The systemic metabolic shifts that occur during aging and the local metabolic alterations of a tumor, its stroma and their communication cooperate to establish…”
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Transient commensal clonal interactions can drive tumor metastasis
Published in Nature communications (16-11-2020)“…The extent and importance of functional heterogeneity and crosstalk between tumor cells is poorly understood. Here, we describe the generation of clonal…”
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FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
Published in Molecular cell (17-08-2023)“…The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that stimulates macromolecule synthesis through transcription, RNA…”
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Identification of novel target genes involved in Indian Fanconi anemia patients using microarray
Published in Gene (01-12-2013)“…Fanconi anemia (FA) is a genetic disorder characterized by progressive bone marrow failure and a predisposition to cancers. Mutations have been documented in…”
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Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication
Published in Science signaling (25-10-2022)“…Multiple coronaviruses have emerged independently in the past 20 years that cause lethal human diseases. Although vaccine development targeting these viruses…”
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GTPBP4 Is a Novel Target of the mTORC1-SRPK2 Axis
Published 01-01-2023“…Altered metabolism is one of the hallmarks of cancer cells, supporting aberrant proliferation and survival in nutrient-scarce and stressful environments. The…”
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Dissertation -
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Abstract 162: Identification of novel targets of Serine/arginine-rich protein-specific kinase 2
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Altered metabolism is one of the hallmarks of cancer cells, supporting aberrant proliferation and survival in nutrient scarce and stressful…”
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Journal Article