Search Results - "Ganesh, Goutham V."

Nrf2 driven macrophage responses in diverse pathophysiological contexts: Disparate pieces from a shared molecular puzzle by V. Ganesh, Goutham, Ganesan, Kumar, Xu, Baojun, Ramkumar, Kunka Mohanram

“…The wide anatomical distribution of macrophages and their vast array of functions match various polarization states and their involvement in homeostasis and…”
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Macrophage mediation in normal and diabetic wound healing responses by Ganesh, Goutham V., Ramkumar, Kunka Mohanram

“…Purpose The failure in timely healing of wounds is a central feature in chronic wounds that leads to physiological, psychological and economic burdens…”
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Pterostilbene accelerates wound healing response in diabetic mice through Nrf2 regulation by Ganesh, Goutham V, Ramkumar, Kunka Mohanram

“…Pterostilbene (PTS), known for its diverse beneficial effects via Nuclear factor erythroid-2 related factor (Nrf2) activation, holds potential for Diabetic…”
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Dysregulation of Nrf2 redox pathway in macrophages under diabetic microenvironment by Ganesh, Goutham V., Ramkumar, Kunka Mohanram

“…In the present study, we characterized the aberration in Nrf2 signaling in macrophages under a hyperglycemic microenvironment that reflects diabetic wounds in…”
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Metabolic reprogramming and immune regulation in viral diseases by Ganesh, Goutham V., Mohanram, Ramkumar K.

“…Summary The recent outbreak and transmission of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) worldwide and the ensuing coronavirus disease…”
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Pterostilbene attenuates hemin-induced dysregulation of macrophage M2 polarization via Nrf2 activation in experimental hyperglycemia by V. Ganesh, Goutham, Ramkumar, Kunka Mohanram

“…Macrophages exhibit a high degree of plasticity that is physiologically relevant in wound healing, and disruption in normal macrophage response leads to…”
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Sodium‐Glucose Cotransporter‐2 Inhibitor Suppresses Endoplasmic Reticulum Stress and Oxidative Stress in Diabetic Nephropathy Through Nrf2 Signaling: A Clinical and Experimental Study by Prasad, Murali Krishna, Victor, Paul S., Ganesh, Goutham V., Juttada, Udayama, Kumpatla, Satyavani, Viswanathan, Vijay, Ramkumar, Kunka Mohanram

“…Diabetic nephropathy (DN), a severe complication of type 2 diabetes mellitus (T2DM), is marked by heightened endoplasmic reticulum stress (ERS) and oxidative…”
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Histone deacetylase inhibitors as antidiabetic agents: Advances and opportunities by Sonthalia, Manisha, Roy, Bhramar Sinha, Chandrawanshi, Divya, Ganesh, Goutham V., Jayasuriya, Ravichandran, Mohandas, Sundhar, Rajagopal, Senthilkumar, Ramkumar, Kunka Mohanram

“…The loss of function or dysfunction of β-cells in the pancreas, attributed to the development of diabetes, involve alterations in genetic and epigenetic…”
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Crosstalk between endoplasmic reticulum stress and oxidative stress in the progression of diabetic nephropathy by Victor, Paul, Umapathy, Dhamodharan, George, Leema, Juttada, Udyama, Ganesh, Goutham V., Amin, Karan Naresh, Viswanathan, Vijay, Ramkumar, Kunka Mohanram

“…Increasing evidence in substantiating the roles of endoplasmic reticulum stress, oxidative stress, and inflammatory responses and their interplay is evident in…”
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Luciferase-Based Reporter System for Investigating GPx4-Mediated Ferroptosis and Its Therapeutic Implications in Diabetes by Mohanram Ramkumar, Kunka, Thasu Susindran, Oviya, Ganesh, Goutham V, Kannan, Harithpriya, Paulmurugan, Ramasamy

“…Ferroptosis, a distinct form of regulated cell death, is characterized by iron-dependent lipid peroxide accumulation in cell membranes from dysregulated…”
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