Search Results - "Ganes, D A"

Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol by Midha, K K, Chakraborty, B S, Ganes, D A, Hawes, E M, Hubbard, J W, Keegan, D L, Korchinski, E D, McKay, G

“…Single oral doses (5 mg) of haloperidol were administered to 36 healthy men (26 black, 10 white) of whom 28 (22 black, 6 white) completed the study. Plasma…”
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Identification in in vivo acetylation pathway for N-dealkylated metabolites of doxylamine in humans by Ganes, D A, Midha, K K

“…1. Metabolites of doxylamine in human urine were separated by g.l.c. and h.p.l.c. and tentatively identified by their mass spectrometric behaviour. 2…”
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Doxylamine metabolism in rat and monkey by Ganes, D A, Hindmarsh, K W, Midha, K K

“…Metabolites of doxylamine obtained with rat-liver homogenate in vitro and from urine of Wistar rats and squirrel monkeys in vivo were examined. The metabolites…”
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Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam by Wagner, J G, Ganes, D A, Midha, K K, Gonzalez-Younes, I, Sackellares, J C, Olson, L D, Affrime, M B, Patrick, J E

“…When disposition is monoexponential, extravascular concentration-time (C, t) data yield both disposition and absorption parameters, the latter via the…”
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Parameters Vm' and Km for elimination of alcohol in young male subjects following low doses of alcohol by Wagner, J G, Wilkinson, P K, Ganes, D A

“…Seventy-four (44 under fasting conditions and 30 following oral liquid meals) sets of post-absorptive human capillary blood alcohol concentration-time data…”
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Estimation of the amount of alcohol ingested from a single blood alcohol concentration by Wagner, J G, Wilkinson, P K, Ganes, D A

“…Capillary blood alcohol concentrations (BAL) measured in 22 young adult male volunteers each of whom received three different treatments of alcohol (total N =…”
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Improved high-performance liquid chromatographic assay for the quantification of 5-bromo-2'-deoxyuridine and 5-bromouracil in plasma by Ganes, D A, Wagner, J G

“…A sensitive and specific procedure using high-performance liquid chromatography (HPLC) was developed for the quantification of 5-bromo-2'-deoxyuridine (BUdR)…”
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Sensitive and specific high-performance liquid chromatographic assay for the quantification of sulforidazine and two diastereomeric sulforidazine-5-sulfoxide metabolites in plasma by Ganes, D A, Midha, K K

“…A sensitive and specific procedure using high-performance liquid chromatography for the quantification of sulforidazine and two diastereomeric…”
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