Search Results - "Gandhi, Vivek"

German cockroach extract prevents IL‐13‐induced CCL26 expression in airway epithelial cells through IL‐13 degradation by Alzahrani, Khadija Rashed, Gomez‐Cardona, Erik, Gandhi, Vivek D., Palikhe, Nami Shrestha, Laratta, Cheryl, Julien, Olivier, Vliagoftis, Harissios

“…Inhaled aeroallergens can directly activate airway epithelial cells (AECs). Exposure to cockroach allergens is a strong risk factor for asthma. Cockroach…”
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Airway epithelium interactions with aeroallergens: role of secreted cytokines and chemokines in innate immunity by Gandhi, Vivek D, Vliagoftis, Harissios

“…Airway epithelial cells are the first line of defense against the constituents of the inhaled air, which include allergens, pathogens, pollutants, and toxic…”
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Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation by Gandhi, Vivek D, Cephus, Jacqueline-Yvonne, Norlander, Allison E, Chowdhury, Nowrin U, Zhang, Jian, Ceneviva, Zachary J, Tannous, Elie, Polosukhin, Vasiliy V, Putz, Nathan D, Wickersham, Nancy, Singh, Amrit, Ware, Lorraine B, Bastarache, Julie A, Shaver, Ciara M, Chu, Hong Wei, Peebles, Jr, R Stokes, Newcomb, Dawn C

“…Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to…”
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ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation by Fuseini, Hubaida, Cephus, Jacqueline-Yvonne, Wu, Pingsheng, Davis, J Brooke, Contreras, Diana C, Gandhi, Vivek D, Rathmell, Jeffrey C, Newcomb, Dawn C

“…Women have increased prevalence of Th17-mediated autoimmune diseases, including lupus and multiple sclerosis, and severe asthma. While estradiol and…”
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Estrogen receptor‐α signaling increases allergen‐induced IL‐33 release and airway inflammation by Cephus, Jacqueline‐Yvonne, Gandhi, Vivek D., Shah, Ruchi, Brooke Davis, Jordan, Fuseini, Hubaida, Yung, Jeffrey A., Zhang, Jian, Kita, Hirohito, Polosukhin, Vasiliy V., Zhou, Weisong, Newcomb, Dawn C.

“…Background Group 2 innate lymphoid cells (ILC2) are stimulated by IL‐33 to increase IL‐5 and IL‐13 production and airway inflammation. While sex hormones…”
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House Dust Mite Interactions with Airway Epithelium: Role in Allergic Airway Inflammation by Gandhi, Vivek D., Davidson, Courtney, Asaduzzaman, Muhammad, Nahirney, Drew, Vliagoftis, Harissios

“…House dust mite (HDM) allergens are the most prevalent allergens associated with asthma and rhinitis around the world. The mechanisms of allergic sensitization…”
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Prostaglandin I2 signaling licenses Treg suppressive function and prevents pathogenic reprogramming by Norlander, Allison E, Bloodworth, Melissa H, Toki, Shinji, Zhang, Jian, Zhou, Weisong, Boyd, Kelli, Polosukhin, Vasiliy V, Cephus, Jacqueline-Yvonne, Ceneviva, Zachary J, Gandhi, Vivek D, Chowdhury, Nowrin U, Charbonnier, Louis-Marie, Rogers, Lisa M, Wang, Janey, Aronoff, David M, Bastarache, Lisa, Newcomb, Dawn C, Chatila, Talal A, Peebles, Jr, R Stokes

“…Tregs restrain both the innate and adaptive immune systems to maintain homeostasis. Allergic airway inflammation, characterized by a Th2 response that results…”
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Increased Protease-Activated Receptor-2 (PAR-2) Expression on CD14++CD16+ Peripheral Blood Monocytes of Patients with Severe Asthma by Shrestha Palikhe, Nami, Nahirney, Drew, Laratta, Cheryl, Gandhi, Vivek Dipak, Vethanayagam, Dilini, Bhutani, Mohit, Mayers, Irvin, Cameron, Lisa, Vliagoftis, Harissios

“…Protease-Activated Receptor-2 (PAR-2), a G protein coupled receptor activated by serine proteases, is widely expressed in humans and is involved in…”
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Insulin decreases expression of the proinflammatory receptor proteinase-activated receptor-2 on human airway epithelial cells by Gandhi, Vivek D., Shrestha Palikhe, Nami, Hamza, Shereen M., Dyck, Jason R.B., Buteau, Jean, Vliagoftis, Harissios

“…Insulin resistance is associated with allergic sensitization and allergic asthma in human subjects2,3 and animal models.4 Recent evidence shows decreased…”
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Characteristics and outcomes of hospitalised adults with COVID-19 in a Global Health Research Network: a cohort study by Zhu, Julia, Wei, Zhongyuan, Suryavanshi, Manasi, Chen, Xiu, Xia, Qian, Jiang, Jenny, Ayodele, Olulade, Bradbury, Brian D, Brooks, Corinne, Brown, Carolyn A, Cheng, Alvan, Critchlow, Cathy W, Devercelli, Giovanna, Gandhi, Vivek, Gondek, Kathleen, Londhe, Ajit A, Ma, Junjie, Jonsson-Funk, Michele, Keenan, Hillary A, Manne, Sudhakar, Ren, Kaili, Sanders, Lynn, Yu, Peter, Zhang, Jie, Zhou, Linyun, Bao, Ying

“…ObjectiveTo examine age, gender, and temporal differences in baseline characteristics and clinical outcomes of adult patients hospitalised with…”
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Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation by Chowdhury, Nowrin U, Cephus, Jacqueline-Yvonne, Henriquez Pilier, Emely, Wolf, Melissa M, Madden, Matthew Z, Kuehnle, Shelby N, McKernan, Kaitlin E, Jennings, Erin Q, Arner, Emily N, Heintzman, Darren R, Chi, Channing, Sugiura, Ayaka, Stier, Matthew T, Voss, Kelsey, Ye, Xiang, Scales, Kennedi L, Krystofiak, Evan S, Gandhi, Vivek D, Guzy, Robert D, Cahill, Katherine N, Sperling, Anne I, Peebles, Jr, R Stokes, Rathmell, Jeffrey C, Newcomb, Dawn C

“…Females have an increased prevalence of many Th17 cell-mediated diseases, including asthma. Androgen signaling decreases Th17 cell-mediated airway…”
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Protease-activated receptor-2: Role in asthma pathogenesis and utility as a biomarker of disease severity by Gandhi, Vivek Dipak, Shrestha Palikhe, Nami, Vliagoftis, Harissios

“…PAR 2 , a receptor activated by serine proteases, has primarily pro-inflammatory roles in the airways and may play a role in asthma pathogenesis. PAR 2 exerts…”
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Stability of peripheral blood immune markers in patients with asthma by Shrestha Palikhe, Nami, Bosonea, Ana-Maria, Laratta, Cheryl, Gandhi, Vivek Dipak, Nahirney, Drew, Hillaby, Angela, Bowen, Miranda, Bhutani, Mohit, Mayers, Irvin, Cameron, Lisa, Vliagoftis, Harissios

“…Asthma is a complex disease with variable course. Efforts to identify biomarkers to predict asthma severity, the course of disease and response to treatment…”
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Infusion Parameters of Patients Initiated on Ig20Gly in a Patient Program by Infusion Schedule by Meckley, Lisa, Wu, Yanyu, Tzivelekis, Spiros, Gandhi, Vivek, Gladiator, Andre

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Androgen Receptor (AR) Signaling Decreases Glutamine Metabolism in Th17 Cells to Decrease House Dust Mite-induced Airway Inflammation by Chowdhury, Nowrin, Cephus, Jacqueline, Voss, Kelsey, Gandhi, Vivek, Peebles, Stokes, Rathmell, Jeffrey, Newcomb, Dawn

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Infusion parameters of 20% subcutaneous immunoglobulin for primary immunodeficiency diseases among patient support program participants by Meckley, Lisa M., Wu, Yanyu, Tzivelekis, Spiros, Gandhi, Vivek, Gladiator, André

“…The safety and efficacy of subcutaneous immune globulin 20% (human) solution (Cuvitru; Ig20Gly) for primary immunodeficiency disease (PID) have been…”
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Effects of Androgen Receptor (AR) Signaling on Airway inflammation in an Obesity-Associated Asthma Model by Chowdhury, Nowrin, Cephus, Jacqueline, Gandhi, Vivek, Peebles, Stokes, Rathmell, Jeffrey, Newcomb, Dawn

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Androgen Receptor Signaling Augments Regulatory T Cell Functions to Attenuate Allergic Airway Inflammation by Gandhi, Vivek, Cephus, Jacqueline, Chowdhury, Nowrin, Norlander, Allison, Peebles, Stokes, Newcomb, Dawn

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Androgen receptor signaling decreases glutaminolysis in Th17 cells to reduce airway inflammation in asthma by Chowdhury, Nowrin U, Cephus, Jacqueline-Yvonne, Voss, Kelsey, Gandhi, Vivek D., Peebles, Ray S, Rathmell, Jeffrey C, Newcomb, Dawn C

“…Women have higher rates of severe asthma compared to men. Severe asthma has increased Th2-mediated eosinophilic and/or Th17-mediated neutrophilic airway…”
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Th2 cell markers in peripheral blood increase during an acute asthma exacerbation by Shrestha Palikhe, Nami, Wu, Yingqi, Konrad, Emily, Gandhi, Vivek Dipak, Rowe, Brian H., Vliagoftis, Harissios, Cameron, Lisa

“…Background Allergic asthma is characterized by type 2 inflammation. We have shown the presence of increased type 2 inflammation in patients with severe asthma…”
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