Search Results - "Gandhi, Mitul"
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Zanubrutinib in patients with previously treated B-cell malignancies intolerant of previous Bruton tyrosine kinase inhibitors in the USA: a phase 2, open-label, single-arm study
Published in The Lancet. Haematology (01-01-2023)“…We hypothesised that zanubrutinib, a highly selective next-generation Bruton tyrosine kinase (BTK) inhibitor, would be a safe and active treatment for patients…”
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A phase II multi-arm study of magrolimab combinations in patients with relapsed/refractory multiple myeloma
Published in Future oncology (London, England) (01-01-2023)“…Magrolimab is a monoclonal antibody that blocks CD47, a ‘do not eat me’ signal overexpressed on tumor cells. CD47 is overexpressed in multiple myeloma (MM),…”
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Pancreatitis in patients treated with brentuximab vedotin: a previously unrecognized serious adverse event
Published in Blood (01-05-2014)Get full text
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Targeted treatment of head and neck squamous-cell carcinoma: potential of lapatinib
Published in OncoTargets and therapy (01-01-2014)“…Squamous-cell cancer of the head and neck is a heterogeneous malignancy with treatment predicated on a multimodality therapy involving surgery, chemotherapy,…”
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Predicting benefit from imatinib: are we close?
Published in Leukemia & lymphoma (01-11-2014)Get full text
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Association of implantable defibrillator therapy risk with body mass index in systolic heart failure
Published in Heart & lung (01-07-2013)“…Abstract Objectives To determine whether risk for implantable cardioverter-defibrillator (ICD) therapy varies by body mass index (BMI) in systolic heart…”
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Brentuximab vedotin in patients with relapsed HIV-related lymphoma
Published in Journal of the National Comprehensive Cancer Network (01-01-2014)“…Lymphoma is a well-recognized complication in patients infected with HIV. Although its incidence has declined since the advent of antiretroviral therapy, it…”
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Phase 1b open-label study of loncastuximab tesirine in combination with other anticancer agents in patients with relapsed/refractory B-cell non-Hodgkin lymphoma (LOTIS-7)
Published in Journal of clinical oncology (01-06-2023)“…TPS7581 Background: Combining agents with different mechanisms of action may enhance treatment (Tx) efficacy in patients (pts) with relapsed/refractory (R/R)…”
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Phase 3 randomized study of loncastuximab tesirine plus rituximab versus immunochemotherapy in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL): LOTIS-5
Published in Journal of clinical oncology (20-05-2021)“…Abstract only TPS7574 Background: Patients (pts) with DLBCL for whom frontline therapy is unsuccessful and who are ineligible for autologous stem cell…”
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Covalent-103: A Phase 1, Open-Label, Dose-Escalation, and Dose-Expansion Study of Bmf-500, an Oral Covalent FLT3 Inhibitor, in Adults with Acute Leukemia (AL)
Published in Blood (02-11-2023)“…Background: FLT3 mutations occur in 25-35% of patients with AML and are associated with poor prognosis. FLT3 mutations are most frequently the result of an…”
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NHL Patients and Nurses in the US Prefer Subcutaneous Rituximab Injection Versus Intravenous Rituximab Infusion: A Real-World Study
Published in Blood (05-11-2020)“…Introduction: In 2017, the US FDA granted approval of a subcutaneous (SC) injection form of rituximab as an alternative means of administration for patients…”
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Safety and Antitumor Activity Study Evaluating Loncastuximab Tesirine and Rituximab Versus Immunochemotherapy in Diffuse Large B-Cell Lymphoma
Published in Blood (05-11-2020)“…Introduction: Patients with diffuse large B-cell lymphoma (DLBCL) who fail immunochemotherapy (IC) and are unsuitable for autologous stem cell transplantation…”
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ABCL-134 Phase Ib Open-Label Study of Loncastuximab Tesirine in Combination With Other Anticancer Agents in Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (LOTIS-7)
Published in Clinical lymphoma, myeloma and leukemia (01-09-2023)“…Combining agents with different mechanisms of action may enhance treatment (Tx) efficacy in patients (pts) with relapsed/refractory (R/R) B-cell non-Hodgkin…”
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Nurse Treatment Preferences Survey for Intravenous Rituximab Infusion Versus Subcutaneous Rituximab Injection: A Real-World Study
Published in Blood (13-11-2019)“…Introduction: The 2017 US FDA approval of a subcutaneous (SC) injection form of rituximab made available an alternative means of administering rituximab for…”
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Phase 3 randomized study of loncastuximab tesirine in combination with rituximab (Lonca-R) versus immunochemotherapy in patients with R/R DLBCL (LOTIS-5)
Published in Journal of clinical oncology (01-06-2022)“…TPS7591 Background: Patients (pts) with refractory or relapsed (R/R) diffuse large B-cell lymphoma (DLBCL) have poor outcomes with standard treatment…”
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Safety and Tolerability of Magrolimab Combinations in Patients with Relapsed/Refractory Multiple Myeloma (RRMM): Safety Run-in Results from a Phase 2 Study
Published in Blood (02-11-2023)“…Background Outcomes remain poor for patients (pts) with RRMM; thus, novel combinations incorporating standard-of-care (SOC) regimens with new drugs possessing…”
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