Search Results - "Gandhi, Gautam K."
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Reduced gap junctional communication among astrocytes in experimental diabetes: Contributions of altered connexin protein levels and oxidative-nitrosative modifications
Published in Journal of neuroscience research (01-12-2011)“…Experimental diabetes increases production of reactive oxygen–nitrogen species and inhibits astrocytic gap junctional communication in tissue culture and brain…”
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Hyperglycaemia and diabetes impair gap junctional communication among astrocytes
Published in ASN neuro (01-01-2010)“…Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is…”
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Selective astrocytic gap junctional trafficking of molecules involved in the glycolytic pathway: impact on cellular brain imaging
Published in Journal of neurochemistry (01-08-2009)“…To assess the specificity of metabolite trafficking among gap junction-coupled astrocytes, we developed novel, real-time, single-cell enzymatic fluorescence…”
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Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons
Published in Journal of neurochemistry (01-10-2009)“…Brain is a highly-oxidative organ, but during activation, glycolytic flux is preferentially up-regulated even though oxygen supply is adequate. The biochemical…”
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Three Randomized Controlled Trials Confirm the Benefits of Mechanical Endovascular Therapy in Acute Ischemic Stroke
Published in World neurosurgery (01-06-2015)Get full text
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Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: Implications for [14C]glucose metabolite trafficking
Published in Journal of neuroscience research (15-11-2007)“…The inferior colliculus has the highest rates of blood flow and metabolism in brain, and functional metabolic activity increases markedly in response to…”
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An anatomic mathematical measurement to find an adequate recipient M4 branch for superficial temporal artery to middle cerebral artery bypass surgery
Published in Neurosurgery (01-09-2007)“…With the recent interest in superficial temporal artery-middle cerebral artery (MCA) bypass for hemodynamic related ischemia, we performed an anatomic study to…”
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Protein kinase Cζ regulates phospholipase D activity in rat-1 fibroblasts expressing the α1A adrenergic receptor
Published in BMC cell biology (21-01-2004)“…BACKGROUND: Phenylephrine (PHE), an α1 adrenergic receptor agonist, increases phospholipase D (PLD) activity, independent of classical and novel protein kinase…”
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Reduced gap junctional communication among astrocytes in experimental diabetes: Contributions of altered connexin protein levels vs. oxidative-nitrosative modifications
Published in Journal of neuroscience research (02-05-2011)“…Experimental diabetes increases production of reactive oxygen-nitrogen species and inhibits astrocytic gap junctional communication in tissue culture and brain…”
Get full text
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Calcium and protein kinase C (PKC)-related kinase mediate alpha 1A-adrenergic receptor-stimulated activation of phospholipase D in rat-1 cells, independent of PKC
Published in The Journal of pharmacology and experimental therapeutics (01-12-2002)“…A previous study conducted in rat-1 cells expressing alpha(1A)-adrenergic receptors showed that phenylephrine (PHE) stimulates phospholipase D (PLD) activity…”
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Protein kinase Czeta regulates phospholipase D activity in rat-1 fibroblasts expressing the alpha1A adrenergic receptor
Published in BMC cell biology (21-01-2004)“…Phenylephrine (PHE), an alpha1 adrenergic receptor agonist, increases phospholipase D (PLD) activity, independent of classical and novel protein kinase C (PKC)…”
Get full text
Journal Article