Search Results - "Gandhi, Aakash Y."

Cytokine-Mediated STAT3 Transcription Supports ATGL/CGI-58-Dependent Adipocyte Lipolysis in Cancer Cachexia by Gandhi, Aakash Y., Yu, Jinhai, Gupta, Arun, Guo, Tong, Iyengar, Puneeth, Infante, Rodney E.

“…Adipose tissue inflammation is observed in multiple metabolically-altered states including cancer-associated cachexia and obesity. Although cachexia is a…”
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Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites by Guggisberg, Ann M, Frasse, Philip M, Jezewski, Andrew J, Kafai, Natasha M, Gandhi, Aakash Y, Erlinger, Samuel J, Odom John, Audrey R

“…In the malaria parasite , synthesis of isoprenoids from glycolytic intermediates is essential for survival. The antimalarial fosmidomycin (FSM) inhibits…”
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Tumor loss-of-function mutations in STK11/LKB1 induce cachexia by Iyengar, Puneeth, Gandhi, Aakash Y, Granados, Jorge, Guo, Tong, Gupta, Arun, Yu, Jinhai, Llano, Ernesto M, Zhang, Faya, Gao, Ang, Kandathil, Asha, Williams, Dorothy, Gao, Boning, Girard, Luc, Malladi, Venkat S, Shelton, John M, Evers, Bret M, Hannan, Raquibul, Ahn, Chul, Minna, John D, Infante, Rodney E

“…Cancer cachexia (CC), a wasting syndrome of muscle and adipose tissue resulting in weight loss, is observed in 50% of patients with solid tumors. Management of…”
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LIFR-α-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease by Guo, Tong, Gupta, Arun, Yu, Jinhai, Granados, Jorge Z., Gandhi, Aakash Y., Evers, Bret M., Iyengar, Puneeth, Infante, Rodney E.

“…The role of chronic adipose inflammation in diet-induced obesity (DIO) and its sequelae including fatty liver disease remains unclear. Leukemia inhibitory…”
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Janus kinase inhibitors suppress cancer cachexia‐associated anorexia and adipose wasting in mice by Arora, Gurpreet K., Gupta, Arun, Guo, Tong, Gandhi, Aakash Y., Laine, Aaron, Williams, Dorothy L., Ahn, Chul, Iyengar, Puneeth, Infante, Rodney E.

“…Background Cachexia, a syndrome of muscle atrophy, adipose loss, and anorexia, is associated with reduced survival in cancer patients. The colon adenocarcinoma…”
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