Search Results - "Gandesiri, Muktheshwar"

Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis by Amin, Amr, Bajbouj, Khuloud, Koch, Adrian, Gandesiri, Muktheshwar, Schneider-Stock, Regine

“…Crocin, a bioactive molecule of saffron, inhibited proliferation of both HCT116 wild-type and HCT116 p53(-/-) cell lines at a concentration of 10 mM. Flow…”
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Apoptosis signalling activated by TNF in the lower gastrointestinal tract--review by Benderska, Natalya, Chakilam, Saritha, Hugle, Manuela, Ivanovska, Jelena, Gandesiri, Muktheshwar, Schulze-Luhrmann, Jan, Bajbouj, Khuloud, Croner, Ronald, Schneider-Stock, Regine

“…The tumor necrosis factor (TNF) gene is an immediate early gene, rapidly transcribed in a variety of cell types following exposure to a broad range of…”
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Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling by El-Najjar, Nahed, Chatila, Manal, Moukadem, Hiba, Vuorela, Heikki, Ocker, Matthias, Gandesiri, Muktheshwar, Schneider-Stock, Regine, Gali-Muhtasib, Hala

“…Thymoquinone (TQ), a component of black seed essential oil, is known to induce apoptotic cell death and oxidative stress, however, the direct involvement of…”
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IL-33 regulates TNF-α dependent effects in synovial fibroblasts by KUNISCH, ELKE, CHAKILAM, SARITHA, GANDESIRI, MUKTHESHWAR, KINNE, RAIMUND W

“…The recently described IL-33 acts as a pro-inflammatory cytokine, inducing the expression of multiple responses in the target cells. Although a nuclear…”
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DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions by Gandesiri, Muktheshwar, Chakilam, Saritha, Ivanovska, Jelena, Benderska, Natalya, Ocker, Matthias, Di Fazio, Pietro, Feoktistova, Maria, Gali-Muhtasib, Hala, Rave-Fränk, Margret, Prante, Olaf, Christiansen, Hans, Leverkus, Martin, Hartmann, Arndt, Schneider-Stock, Regine

“…The histone deacetylase inhibitor (HDACi) LBH589 has been verified as an effective anticancer agent. The identification and characterization of new targets for…”
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DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells by Benderska, Natalya, Ivanovska, Jelena, Rau, Tilman T, Schulze-Luehrmann, Jan, Mohan, Suma, Chakilam, Saritha, Gandesiri, Muktheshwar, Ziesché, Elisabeth, Fischer, Thomas, Söder, Stephan, Agaimy, Abbas, Distel, Luitpold, Sticht, Heinrich, Mahadevan, Vijayalakshmi, Schneider-Stock, Regine

“…Death-associated protein kinase (DAPK) is a serine-threonine kinase with tumor suppressor function. Previously, we demonstrated that tumor necrosis factor…”
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In vivo monitoring of the anti-angiogenic therapeutic effect of the pan-deacetylase inhibitor panobinostat by small animal PET in a mouse model of gastrointestinal cancers by Maschauer, Simone, Gahr, Susanne, Gandesiri, Muktheshwar, Tripal, Philipp, Schneider-Stock, Regine, Kuwert, Torsten, Ocker, Matthias, Prante, Olaf

“…Abstract Introduction Deacetylase inhibitors have recently been established as a novel therapeutic approach to solid and hematologic cancers and have also been…”
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Identification of DAPK as a scaffold protein for the LIMK/cofilin complex in TNF-induced apoptosis by Ivanovska, Jelena, Tregubova, Alexandra, Mahadevan, Vijayalakshmi, Chakilam, Saritha, Gandesiri, Muktheshwar, Benderska, Natalya, Ettle, Benjamin, Hartmann, Arndt, Söder, Stephan, Ziesché, Elisabeth, Fischer, Thomas, Lautscham, Lena, Fabry, Ben, Segerer, Gabriela, Gohla, Antje, Schneider-Stock, Regine

“…The role of cytoskeleton-associated proteins during TNF-induced apoptosis is not fully understood. A potential candidate kinase that might connect TNF…”
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Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells by Chakilam, Saritha, Gandesiri, Muktheshwar, Rau, Tilman T, Agaimy, Abbas, Vijayalakshmi, Mahadevan, Ivanovska, Jelena, Wirtz, Ralph M, Schulze-Luehrmann, Jan, Benderska, Natalya, Wittkopf, Nadine, Chellappan, Ajithavalli, Ruemmele, Petra, Vieth, Michael, Rave-Fränk, Margret, Christiansen, Hans, Hartmann, Arndt, Neufert, Clemens, Atreya, Raja, Becker, Christoph, Steinberg, Pablo, Schneider-Stock, Regine

“…The TNF-IL-6-STAT3 pathway plays a crucial role in promoting ulcerative colitis-associated carcinoma (UCC). To date, the negative regulation of STAT3 is poorly…”
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Erratum to: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions by Gandesiri, Muktheshwar, Chakilam, Saritha, Ivanovska, Jelena, Benderska, Natalya, Ocker, Matthias, Di Fazio, Pietro, Feoktistova, Maria, Gali-Muhtasib, Hala, Rave-Fränk, Margret, Prante, Olaf, Christiansen, Hans, Leverkus, Martin, Hartmann, Arndt, Schneider-Stock, Regine

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Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF α in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis by Kunisch, Elke, Gandesiri, Muktheshwar, Fuhrmann, Reneé, Roth, Andreas, Winter, Rando, Kinne, Raimund W

“…Objective: To examine the relative importance of tumour necrosis factor-receptor 1 (TNF-R1) and TNF-R2 and their signalling pathways for pro-inflammatory and…”
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DAPK-HSF1 interaction as a new positive feedback loop for TNF-induced apoptosis in colorectal cancer cells by Benderska, Natalya, Ivanovska, Jelena, Rau, Tilman T., Schulze-Luehrmann, Jan, Mohan, Suma, Chakilam, Saritha, Gandesiri, Muktheshwar, Ziesché, Elisabeth, Fischer, Thomas, Söder, Stephan, Agaimy, Abbas, Distel, Luitpold, Sticht, Heinrich, Mahadevan, Vijayalakshmi, Schneider-Stock, Regine

“…Death-associated protein kinase (DAPK) is a serine-threonine kinase with tumor suppressor function. Previously we demonstrated that TNF induced DAPK-mediated…”
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LBH589-Induced DAPK Activation Triggers Apoptosis and Autophagy in Human Colon Tumor Cells by Gandesiri, Muktheshwar

“…Histone deacetylase inhibitors (HDACi) are relatively new class of anticancer agents displaying pleiotropic activities against various cancers. Among HDACi,…”
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Abstract 4673A: DAPK-mediated phosphorylation of HSF1 enhances apoptosis level upon TNF in colorectal carcinoma cells by Benderska, Natalya, Rau, Tilman, Ivanovska, Jelena, Chakilam, Saritha, Gandesiri, Muktheshwar, Ziesche, Elisabeth, Agaimy, Abbas, Schulze-Luehrmann, Jan, Distel, Luitpold, Fischer, Thomas, Sticht, Heinrich, Schneider-Stock, Regine

“…Abstract Objectives: Tumor necrosis factor ≤ (TNF) is an inflammatory cytokine, which is released upon different stimuli, including irradiation. Recently it…”
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Abstract 4779: TNF-induced Cofilin 1 phosphorylation by LIMK in colorectal tumor cells by Ivanovska, Jelena, Ettle, Benjamin, Benderska, Natalya, Chakilam, Saritha, Gandesiri, Muktheshwar, Ziesché, Elisabeth, Hartmann, Arndt, Agaimy, Abbas, Fischer, Thomas, Gohla, Antje, Fabry, Ben, Schneider-Stock, Regine

“…Abstract Objectives: Recently, we have shown that the pro-inflammatory cytokine TNF induces apoptosis in HCT116 colorectal tumor cells. Among the first…”
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Abstract 3649: DAPK-dependent apoptosis induction after treatment of colorectal tumor cells with the histone deacetylase inhibitor panobinostat (LBH589) by Gandesiri, Muktheshwar, Chakilam, Saritha, Ocker, Matthias, Christiansen, Hans, Rave-Fraenk, Margret, Rauchschwalbe, Sonja, Ivanovska, Jelena, Hartmann, Arndt, Schneider-Stock, Regine

“…Abstract Objectives: Among Histone deacetylase inhibitors (HDACi), panobinostat is a relatively new compound showing potent antitumor activities. Although the…”
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RETRACTED: Death-Associated Protein Kinase Controls STAT3 Activity in Intestinal Epithelial Cells by Chakilam, Saritha, Gandesiri, Muktheshwar, Rau, Tilman T, Agaimy, Abbas, Vijayalakshmi, Mahadevan, Ivanovska, Jelena, Wirtz, Ralph M, Schulze-Luehrmann, Jan, Benderska, Natalya, Wittkopf, Nadine, Chellappan, Ajithavalli, Ruemmele, Petra, Vieth, Michael, Rave-Fränk, Margret, Christiansen, Hans, Hartmann, Arndt, Neufert, Clemens, Atreya, Raja, Becker, Christoph, Steinberg, Pablo, Schneider-Stock, Regine

“…This article has been retracted: please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy ). This article has been…”
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Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF   in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis by Kunisch, E., Gandesiri, M., Fuhrmann, R., Roth, A., Winter, R., Kinne, R. W

“…Objective: To examine the relative importance of tumour necrosis factor-receptor 1 (TNF-R1) and TNF-R2 and their signalling pathways for pro-inflammatory and…”
Get full text