Search Results - "Ganderton, Tim"
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The Chlamydia trachomatis PmpD adhesin forms higher order structures through disulphide-mediated covalent interactions
Published in PloS one (18-06-2018)“…Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterial pathogen, and the leading cause of infectious blindness worldwide. We have…”
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Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain
Published in Blood (10-11-2011)“…VWF is a plasma protein that binds platelets to an injured vascular wall during thrombosis. When exposed to the shear forces found in flowing blood, VWF…”
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Journal Article -
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Role of Thrombospondin-1 in Control of von Willebrand Factor Multimer Size in Mice
Published in The Journal of biological chemistry (14-05-2004)“…Plasma von Willebrand factor (VWF) is a multimeric glycoprotein from endothelial cells and platelets that mediates adhesion of platelets to sites of vascular…”
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Journal Article -
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Evidence for Control of von Willebrand Factor Multimer Size by Intramolecular Thiol-Disulfide Exchange
Published in Blood (16-11-2005)“…Plasma von Willebrand factor (VWF) is a multimeric glycoprotein from endothelial cells and platelets that mediates adhesion of platelets to sites of vascular…”
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Journal Article