Search Results - "Ganapathi, Usha"

Adipose Tissue Regulates Pulmonary Pathology during TB Infection by Ayyappan, Janeesh Plakkal, Ganapathi, Usha, Lizardo, Kezia, Vinnard, Christopher, Subbian, Selvakumar, Perlin, David S., Nagajyothi, Jyothi F

“…Tuberculosis (TB), caused by infection, remains a major cause of mortality and morbidity worldwide. One-third of the world population is infected with , and…”
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Decreased CD40L through disrupted transcriptional stability affects the autoimmune response in a sex-dependent manner in a GVHD model of SLE by De Maio, Diego Javier Prado, Ganapathi, Usha, Covey, Lori

“…Increased levels of CD40L have been observed on CD4 T cells of patients with systemic lupus erythematosus (SLE) and in several murine models of lupus-like…”
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A Posttranscriptional pathway of CD40L mRNA Stability is Required for the Development of an Optimal Humoral Immune Response by Narayanan, Bitha, Prado de Maio, Diego, La Porta, James, Voskoboynik, Yekaterina, Ganapathi, Usha, Xie, Ping, Covey, Lori R.

“…CD40L mRNA stability is dependent on an activation-induced pathway that is mediated by the binding of RNA binding complexes containing the multifunctional RNA…”
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Activation-dependent post-transcriptional regulation of CD40L mediates B cell development and survival in germinal centers by De Maio, Diego Javier Prado, Narayanan, Bitha, La Porta, James, Ganapathi, Usha, Xie, Ping, Covey, Lori R

“…We have described a posttranscriptional pathway of induced mRNA stability that occurs at late times of T cell activation and is engaged by the binding of a…”
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Abnormal innate immune responses and associated genetic factors in Multisystem Inflammatory Syndrome in Children (MIS-C) by Khan, Rehan, Ji, Weizhen, Guzman-Rivera, Jeisac, Mishra, Abhilasha, Richlin, Benjamin, Gaur, Sunanda, Singh, Aalok, Bukulmez, Hulya, Kaelber, David, Riordan, Mary, Kimura, Yukiko, Ganapathi, Usha, Michailidis, Ioannis, Ukey, Rahul, Casseus, Myriam, Andrews, Tracy, Roy, Jason

“…Multisystem inflammatory syndrome in children (MIS-C) is a rare, severe complication of COVID-19 characterized by multi-lineage immune activation and…”
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A Posttranscriptional Pathway of CD40 Ligand mRNA Stability Is Required for the Development of an Optimal Humoral Immune Response by Narayanan, Bitha, Prado de Maio, Diego, La Porta, James, Voskoboynik, Yekaterina, Ganapathi, Usha, Xie, Ping, Covey, Lori R.

“…CD40 ligand (CD40L) mRNA stability is dependent on an activation-induced pathway that is mediated by the binding complexes containing the multifunctional…”
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Drug delivery strategies and systems for HIV/AIDS pre-exposure prophylaxis and treatment by Nelson, Antoinette G., Zhang, Xiaoping, Ganapathi, Usha, Szekely, Zoltan, Flexner, Charles W., Owen, Andrew, Sinko, Patrick J.

“…The year 2016 will mark an important milestone — the 35th anniversary of the first reported cases of HIV/AIDS. Antiretroviral Therapy (ART) including Highly…”
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Diet Alters Serum Metabolomic Profiling in the Mouse Model of Chronic Chagas Cardiomyopathy by Nagajyothi, Jyothi F., Qiu, Yunping, Dutra, Walderez Ornelas, Ganapathi, Usha, Ayyappan, Janeesh Plakkal, Lizardo, Kezia, Weiss, Louis M.

“…Chagas disease is caused by Trypanosoma cruzi which is endemic in Latin America. T. cruzi infection results in a latent infection with approximately a third of…”
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Colorectal delivery and retention of PEG-Amprenavir-Bac7 nanoconjugates—proof of concept for HIV mucosal pre-exposure prophylaxis by Samizadeh, Mahta, Zhang, Xiaoping, Gunaseelan, Simi, Nelson, Antoinette G., Palombo, Matthew S., Myers, Daniel R., Singh, Yashveer, Ganapathi, Usha, Szekely, Zoltan, Sinko, Patrick J.

“…Local delivery of anti-HIV drugs to the colorectal mucosa, a major site of HIV replication, and their retention within mucosal tissue would allow for a…”
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