Search Results - "Ganai, Bashir A."

A Potent Inhibitor of Phosphoinositide 3-Kinase (PI3K) and Mitogen Activated Protein (MAP) Kinase Signalling, Quercetin (3, 3', 4', 5, 7-Pentahydroxyflavone) Promotes Cell Death in Ultraviolet (UV)-B-Irradiated B16F10 Melanoma Cells by Rafiq, Rather A, Quadri, Afnan, Nazir, Lone A, Peerzada, Kaiser, Ganai, Bashir A, Tasduq, Sheikh A

“…Ultraviolet (UV) radiation-induced skin damage contributes strongly to the formation of melanoma, a highly lethal form of skin cancer. Quercetin (Qu), the most…”
Get full text

Chemical composition, antioxidant and antibacterial activities of the leaf essential oil of Juglans regia L. and its constituents by Rather, Manzoor A., Dar, Bilal A., Dar, Mohd Yousuf, Wani, Bilal A., Shah, Wajahat A., Bhat, Bilal A., Ganai, Bashir A., Bhat, Khursheed A., Anand, Rajneesh, Qurishi, Mushtaq A.

“…The essential oil from the leaves of Juglans regia L. (Juglandaceae) growing wild in Kashmir (India) was obtained by hydrodistillation and analysed by a…”
Get full text

Induction of apoptosis in human pancreatic MiaPaCa-2 cells through the loss of mitochondrial membrane potential (ΔΨm) by Gentiana kurroo root extract and LC-ESI-MS analysis of its principal constituents by Wani, Bilal A., Ramamoorthy, D., Rather, Manzoor A., Arumugam, N., Qazi, Asif Khurshid, Majeed, Rabiya, Hamid, Abid, Ganie, Showkat A., Ganai, Bashir A., Anand, Rajneesh, Gupta, Ajai P.

“…The objective of the current study was to evaluate the methanolic root extract of Gentiana kurroo for antioxidant and antiproliferative activities as well as…”
Get full text

Esophageal Cancer: Associated Factors with Special Reference to the Kashmir Valley by Rasool, Sabha, Ganai, Bashir A, Sameer, A Syed, Masood, Akbar

“…Esophageal cancer is one of the most common cancers worldwide. It is a multifactorial disease, and no single agent has been identified so far as the sole cause…”
Get full text

Antimutagenic activity of compounds isolated from Ajuga bracteosa Wall ex. Benth against EMS induced mutagenicity in mice by Ganaie, Hilal Ahmad, Ali, Md. Niamat, Ganai, Bashir A., Bashir, Samirul

“…Schematic representation of compounds isolated from Ajuga bracteosa and their antimutagenic activity. [Display omitted] •Four compounds 1) 14,…”
Get full text

Association of promoter methylation of RASSF1A and KRAS mutations in non-small cell lung carcinoma in Kashmiri population (India) by Din Shah, Naseer Ue, Ali, Md Niamat, Ganai, Bashir A., Mudassar, Syed, Khan, Mosin Saleem, Kour, Jasbir, Waza, Ajaz Ahmad, Rasool, Malik Tariq, Lone, Aabid Maqbool

“…Non-small cell lung carcinoma (NSCLC) incidence and progression is increasing because of genetic and epigenetic changes. The mutations in the Kirsten rat…”
Get full text

Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa by Tantry, Mudasir A., Idris, Ahmed S., Williamson, John S., Shafi, Tasfi, Dar, Jehangir S., Malik, Tauseef A., Ganai, Bashir A., Shawl, Abdul S.

“…The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of…”
Get full text

Genetic variations in key inflammatory cytokines exacerbates the risk of diabetic nephropathy by influencing the gene expression by Hameed, Iqra, Masoodi, Shariq R., Malik, Perveez A., Mir, Shahnaz A., Ghazanfar, Khalid, Ganai, Bashir A.

“…Diabetic nephropathy is the single strongest predictor of mortality in patients with diabetes. The development of overt nephropathy involves important…”
Get full text

Type 2 diabetes mellitus: From a metabolic disorder to an inflammatory condition by Hameed, Iqra, Masoodi, Shariq R, Mir, Shahnaz A, Nabi, Mudasar, Ghazanfar, Khalid, Ganai, Bashir A

“…Diabetes mellitus is increasing at an alarming rate and has become a global challenge. Insulin resistance in target tissues and a relative deficiency of…”
Get full text

Evaluating the Biocontrol Efficacy and Antioxidant Potential of Phellinus caribaeo‐quercicola—A First Report Dual‐Action Endophyte From Inula racemosa Hook. F by Majid, Misbah, Wani, Abdul H., Ganai, Bashir A.

“…ABSTRACT Phellinus caribaeo‐quercicola is a basidiomycetous fungus, isolated as an endophyte in this study from the healthy and symptomless leaves of Inula…”
Get full text

β-Cell protective efficacy, hypoglycemic and hypolipidemic effects of extracts of Achillea millifolium in diabetic rats by Mustafa, Khalid G., Ganai, Bashir A., Akbar, Seema, Dar, Mohamad Y., Masood, Akbar

“…To evaluate the therapeutic uses of Achillea millifolium in diabetic rats. Diabetes was induced by single intraperitoneal injection of freshly prepared…”
Get full text

Evaluation of Antiarthritic Potential of Methanolic Extract of ＂Gentiana kurroo＂ Royle by Mubashir, Khan, Ganai, Bashir A., Ghazanfar, Khalid, Akbar, Seema

“…Rheumatoid arthritis is a systemic disorder which involves the activation of immune system against the self-tissues. The main targets of this disease are the…”
Get full text

Fusobacterium nucleatum: an emerging bug in colorectal tumorigenesis by Bashir, Arif, Miskeen, Abid Y., Bhat, Ashaqullah, Fazili, Khalid M., Ganai, Bashir A.

“…The human intestinal microbiota is a plethora of diverse microbial species, wherein certain bacteria considered as driver bacteria with procarcinogenic…”
Get full text

Variation in root morphology, enhancement in anti-oxidative enzyme responses and improved arbutin and bergenin levels in Bergenia ciliata (Haw.) Sternb. raised in vitro via EMS and gamma irradiations by Rafi, Sabreena, Kamili, Azra N., Ganai, Bashir A., Parray, Javid A., Jan, Sumira

“…Plant cells develop defence mechanisms in response to mutagen stress which leads to modulation of certain metabolic and defensive pathways. Owing to alteration…”
Get full text

Association of TCF7L2 Gene Variant (rs12255372) with Polycystic Ovary Syndrome and its Effect Modification of the Disease Phenotype by Rashid, Rabiya, Shah, Idrees A., Makhdoomi, Mudassir Jan, Rashid, Aafia, Godha, Meena, Ganai, Bashir A., Ganie, Mohd Ashraf

“…Polycystic ovary syndrome (PCOS) and type-2 diabetes mellitus (T2DM) share common genetic features. Transcription factor 7-like-2 (TCF7L2 ) is consistently…”
Get full text

Connexin 43 and ATP-sensitive potassium channels crosstalk: a missing link in hypoxia/ischemia stress by Ahmad Waza, Ajaz, Ahmad Bhat, Shabir, Ul Hussain, Mahboob, Ganai, Bashir A.

“…Connexin 43 (Cx43) is a gap junction protein expressed in various tissues and organs of vertebrates. Besides functioning as a gap junction, Cx43 also regulates…”
Get full text

Morphological and molecular characterization and new distributional record of Tetrastichus miser (Nees, 1834) (Hymenoptera: Chalcidoidea: Eulophidae) from Kashmir by RASOOL, Ajaz, GANAI, Bashir A., SANTHOSH, Shreevihar, AHMAD, Tariq

“…Tetrastichus miser (Nees, 1834) (Hymenoptera: Eulophidae: Tetrastichinae) is a parasitoid of Curculioninae and Scolytinae infesting various trees of economic…”
Get full text

Family history of menstrual irregularity or diabetes mellitus enhances the susceptibility to polycystic ovary syndrome among subjects harboring rs7903146 genetic variant of TCF7L2 by Rashid, Rabiya, Shah, Idrees A., Asrar, Mir M., Godha, Meena, Ganai, Bashir A., Ganie, Mohd Ashraf

“…Purpose TCF7L2  mediated Wnt signaling cascade regulates glucose homeostasis by orchestrating expression, processing, and hepatic clearance of insulin. Type 2…”
Get full text

Association of Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor gamma 2 (PPARγ2) Gene with Type 2 Diabetes Mellitus in Ethnic Kashmiri Population by Majid, Misbah, Masood, Akbar, Kadla, Showkat Ahmad, Hameed, Iqra, Ganai, Bashir A.

“…ABSTRACT Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia associated with insulin resistance and relative insulin deficiency. T2DM is…”
Get full text

Bioassay-guided isolation and identification of antimutagenic compounds from Morina coulteriana and evaluation of its therapeutic potential by Kour, Jasbir, Lone, Bashir Ahmad, Kumar, Amit, Ganai, Bashir A., Yadav, Govind, Gupta, Prasoon, Ali, Md.Niamat, Akbar, Seema

“…•Morina coulteriana and its fractions showed significant antimutagenic potential. Ethyl acetate fraction was the most active fraction in both in vitro (66.13 %…”
Get full text