Search Results - "Gan, Xiaoxian"

CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine by Gu, Ying, Chen, Ting, Meng, Zhipeng, Gan, Yichao, Xu, Xiaohua, Lou, Guiyu, Li, Hongzhi, Gan, Xiaoxian, Zhou, Hong, Tang, Jinfen, Xu, Genbo, Huang, Liansheng, Zhang, Xiaohong, Fang, Yongming, Wang, Kai, Zheng, Shu, Huang, Wendong, Xu, Rongzhen

“…Bcr-Abl tyrosine kinase inhibitors (TKIs) have been a remarkable success for the treatment of Ph+ chronic myeloid leukemia (CML). However, a significant…”
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Novel synthetic tosyl chloride-berbamine regresses lethal MYC-positive leukemia by targeting CaMKIIγ/Myc axis by Yu, Qingfeng, Wang, Ping, Yang, Linlin, Wu, Zhaoxing, Li, Shu, Xu, Ying, Wu, Bowen, Ma, An, Gan, Xiaoxian, Xu, Rongzhen

“…[Display omitted] Proto-oncogene Myc, a key transcription factor, is frequently deregulated in human leukemia with aggressive and poor clinical outcome, but…”
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Linalool preferentially induces robust apoptosis of a variety of leukemia cells via upregulating p53 and cyclin-dependent kinase inhibitors by Gu, Ying, Ting, Zhang, Qiu, Xi, Zhang, Xuzhao, Gan, Xiaoxian, Fang, Yongming, Xu, Xiaohua, Xu, Rongzhen

“…Abstract Linalool, a natural small molecule monoterpene, has been shown to have anti-tumor activity against several human tumor cell lines in vitro ; however,…”
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Molecular differentiation of Angiostrongylus taxa (Nematoda: Angiostrongylidae) by cytochrome c oxidase subunit I (COI) gene sequences by Eamsobhana, Praphathip, Lim, Phaik Eem, Solano, Gabriela, Zhang, Hongman, Gan, Xiaoxian, Yong, Hoi Sen

“…▶ Molecular differentiation and phylogeny of Angiostrongylus taxa. ▶ COI gene sequences of Angiostrongylus. ▶ Phylogeography of Angiostrongylus cantonensis…”
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Molecular differentiation and phylogenetic relationships of three Angiostrongylus species and Angiostrongylus cantonensis geographical isolates based on a 66-kDa protein gene of A. cantonensis (Nematoda: Angiostrongylidae) by Eamsobhana, Praphathip, Lim, Phaik Eem, Zhang, Hongman, Gan, Xiaoxian, Yong, Hoi Sen

“…The phylogenetic relationships and molecular differentiation of three species of angiostrongylid nematodes ( Angiostrongylus cantonensis, Angiostrongylus…”
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Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia by Xu, Rongzhen, Yu, Yingzi, Zheng, Shu, Zhao, Xiaoying, Dong, Qinghua, He, Zhiwen, Liang, Yun, Lu, Qinghua, Fang, Yongmin, Gan, Xiaoxian, Xu, Xiaohua, Zhang, Suzhan, Dong, Qi, Zhang, Xiaohong, Feng, Gen-Sheng

“…Shp2 tyrosine phosphatase plays a critical role in hematopoiesis, and dominant active mutations have been detected in the human gene PTPN11, encoding Shp2, in…”
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Pb(Zr0.95Ti0.05)O3 powders prepared by aqueous Pechini method using one-step pyrolysis process: characterization and porous ceramics by Qiu, Shaojun, Gao, Chao, Zheng, Xiaodong, Chen, Jin, Yang, Chen, Gan, Xiaoxian, Fan, Huiqing

“…Zr-riched lead zirconate titanate, Pb(Zr₀.₉₅Ti₀.₀₅)O₃ (PZT 95/5) powders were prepared using lead acetate, zirconium oxynitrate, and titanium sulfate by…”
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A Schistosoma japonicum very low-density lipoprotein-binding protein by Fan, Jinjiang, Gan, Xiaoxian, Yang, Wen, Shen, Liying, McManus, Donald P, Brindley, Paul J

“…Schistosomes acquire fatty acids from their hosts, although how these parasites bind human low-density lipoproteins (LDL) and like molecules that transport…”
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An Azido Ester Plasticizer, 1,3-Di(Azidoacetoxy)-2,2-Di(Azidomethyl)Propane (PEAA): Synthesis, Characterization and Thermal Properties by Shaojun, Qiu, Huiqing, Fan, Chao, Gao, Xiaodong, Zheng, Xiaoxian, Gan

“…A polyazido compound, 1,3‐di(azidoacetoxy)‐2,2‐di(azidomethyl)propane (PEAA) was synthesized and identified. Thermal properties of PEAA, such as the glass…”
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Synthesis and properties of poly-isocyanate energetic curing agent by Xiaodong, Zheng, Shaojun, Qiu, Limin, Feng, Mintao, Wang, Hongli, Li, Xiaoxian, Gan, Zhizhong, Zhang

“…SummaryTwo tetrafunctional poly-isocyanate energetic curing agents with different molecular weight (EO03-1 and EO03-3) were synthesized via reaction of azido…”
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Targeting the Ca2+/Calmodulin-dependent protein kinase II by Tetrandrine in human liver cancer cells by Huang, Tracy, Xu, Senlin, Deo, Rucha, Ma, An, Li, Hongzhi, Ma, Ke, Gan, Xiaoxian

“…Hepatocellular carcinoma (HCC) is the most prevalent malignancy in liver and a leading cause of cancer-related deaths. Despite the pressing need for treatment…”
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Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma by Gu, Ying, Zhang, Jiawei, Ma, Xiaoxiao, Kim, Byung-wook, Wang, Hailong, Li, Jinfan, Pan, Yi, Xu, Yang, Ding, Lili, Yang, Lu, Guo, Chao, Wu, Xiwei, Wu, Jun, Wu, Kirk, Gan, Xiaoxian, Li, Gang, Li, Ling, Forman, Stephen J., Chan, Wing-Chung, Xu, Rongzhen, Huang, Wendong

“…Although high c-Myc protein expression is observed alongside MYC amplification in some cancers, in most cases protein overexpression occurs in the absence of…”
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Aberrant activation of RPB1 is critical for cell overgrowth in acute myeloid leukemia by Yu, Qingfeng, Xu, Ying, Zhuang, Haifeng, Wu, Zhaoxing, Zhang, Lei, Li, Jinfan, Yang, Linlin, Wu, Bowen, Wang, Ping, Zhang, Xuzhao, Gan, Xiaoxian, Liang, Yun, Zheng, Shu, Yu, Xiaofang, Gu, Ying, Xu, Rongzhen

“…Acute myeloid leukemia (AML) is a group of highly aggressive malignancies with a 5-year overall survival of less than 40%. Cell overgrowth with defective…”
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A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors by Xu, Ying, Yu, Qingfeng, Wang, Ping, Wu, Zhaoxing, Zhang, Lei, Wu, Shuigao, Li, Mengyuan, Wu, Bowen, Li, Hongzhi, Zhuang, Haifeng, Zhang, Xuzhao, Huang, Yu, Gan, Xiaoxian, Xu, Rongzhen

“…MYC oncogene is involved in the majority of human cancers and is often associated with poor outcomes, rendering it an extraordinarily desirable target, but…”
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Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia by Lu, Xiaoya, Zhuang, Haifeng, Yu, Qingfeng, Zhang, Xuzhao, Wu, Zhaoxing, Zhang, Lei, Xu, Ying, Wu, Bowen, Yang, Linlin, Ma, An, Gan, Xiaoxian, Yu, Xiaofang, Shen, Jianping, Xu, Rongzhen

“…Identifying and targeting oncogenic fusion genes have revolutionized the treatment of leukemia, such as PML-RARα fusion gene in acute promyelocytic leukemia…”
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CAMK2γ in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation by Ma, X, Meng, Z, Jin, L, Xiao, Z, Wang, X, Tsark, W M, Ding, L, Gu, Y, Zhang, J, Kim, B, He, M, Gan, X, Shively, J E, Yu, H, Xu, R, Huang, W

“…Inflammation is one of the major risk factors for cancer. Here, we show that calcium/calmodulin-dependent protein kinase II gamma (CAMK2γ) in intestinal…”
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Identification of the novel Np17 oncogene in human leukemia by Wu, Bowen, Gan, Yichao, Xu, Ying, Wu, Zhaoxing, Xu, Ganyu, Wang, Ping, Wang, Chen, Meng, Zhipeng, Li, Mengyuan, Zhang, Jiawei, Zhuang, Haifeng, Zhang, Xuzhao, Yang, Linlin, Li, Jinfan, Gan, Xiaoxian, Yu, Xiaofang, Huang, Wendong, Gu, Ying, Xu, Rongzhen

“…We previously defined the HERV-K Np9 as a viral oncogene. Here we report the discovery of a novel oncogene, Np17, which is homologous to the viral Np9 gene and…”
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Activation of CaMKIIγ potentiates T-cell acute lymphoblastic leukemia leukemogenesis via phosphorylating FOXO3a by Jiang, Xudong, Wu, Zhaoxing, Lu, Xiaoya, Zhang, Xuzhao, Yu, Qingfeng, Gan, Yichao, Wu, Bowen, Xu, Ying, Zheng, Weiwei, Zhang, Lei, Xu, Fei, Ma, An, Gan, Xiaoxian, Huang, Silvia, Yu, Xiaofang, Huang, Wendong, Xu, Rongzhen

“…Ca /calmodulin-dependent protein kinase II γ (CaMKIIγ) can regulate the proliferation and differentiation of myeloid leukemia cells and accelerate chronic…”
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CAMK2γ antagonizes mTORC1 activation during hepatocarcinogenesis by Meng, Z, Ma, X, Du, J, Wang, X, He, M, Gu, Y, Zhang, J, Han, W, Fang, Z, Gan, X, Van Ness, C, Fu, X, Schones, D E, Xu, R, Huang, W

“…Hepatocellular carcinoma (HCC) is one of the most deadly cancers that still lacks effective treatments. Dysregulation of kinase signaling has frequently been…”
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A simple, rapid, and sensitive integrated protein microarray for simultaneous detection of multiple antigens and antibodies of five human hepatitis viruses (HBV, HCV, HDV, HEV, and HGV) by Xu, Rongzhen, Gan, Xiaoxian, Fang, Yongming, Zheng, Shu, Dong, Qi

“…Protein microarrays for parallel detection of multiple viral antigens and antibodies have not yet been described in the field of human hepatitis virus…”
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