Search Results - "Gan, Shenglian"

Dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial by Zhu, Dalong, Li, Xiaoying, Ma, Jianhua, Zeng, Jiao’e, Gan, Shenglian, Dong, Xiaolin, Yang, Jing, Lin, Xiaohong, Cai, Hanqing, Song, Weihong, Li, Xuefeng, Zhang, Keqin, Zhang, Qiu, Lu, Yibing, Bu, Ruifang, Shao, Huige, Wang, Guixia, Yuan, Guoyue, Ran, Xingwu, Liao, Lin, Zhao, Wenjuan, Li, Ping, Sun, Li, Shi, Lixin, Jiang, Zhaoshun, Xue, Yaoming, Jiang, Hongwei, Li, Quanmin, Li, Zongbao, Fu, Maoxiong, Liang, Zerong, Guo, Lian, Liu, Ming, Xu, Chun, Li, Wenhui, Yu, Xuefeng, Qin, Guijun, Yang, Zhou, Su, Benli, Zeng, Longyi, Geng, Houfa, Shi, Yongquan, Zhao, Yu, Zhang, Yi, Yang, Wenying, Chen, Li

“…Improving glucose sensitivity remains an unmet medical need in treating type 2 diabetes (T2D). Dorzagliatin is a dual-acting, orally bioavailable glucokinase…”
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Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio is a more powerful marker than TyG index for predicting metabolic syndrome in patients with type 2 diabetes mellitus by Gong, Shijun, Gan, Shenglian, Zhang, YuHua, Zhou, HaiFeng, Zhou, Quan

“…Purpose The prevalence of metabolic syndrome (MetS) is increasing globally and has become a global and national public health problem that cannot be ignored as…”
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Efficacy and safety of GLP-1 analog ecnoglutide in adults with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 2 trial by Zhu, Dalong, Wang, Weimin, Tong, Guoyu, Ma, Guoqing, Ma, Jianhua, Han, Jie, Zhang, Xin, Liu, Yang, Gan, Shenglian, Qin, Hong, Zheng, Qing, Ning, Jing, Zhu, Zhiyi, Guo, Mengying, Bu, Yue, Li, Yao, Jones, Catherine L., Fenaux, Martijn, Junaidi, Mohammed K., Xu, Susan, Pan, Hai

“…Glucagon-like peptide-1 (GLP-1) analogs are important therapeutics for type 2 diabetes and obesity. Ecnoglutide (XW003) is a novel, long-acting GLP-1 analog…”
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Visceral fat area is more strongly associated with arterial stiffness than abdominal subcutaneous fat area in Chinese patients with type 2 diabetes by Mao, Jing, Gan, Shenglian, Gong, Shijun, Zhou, Quan, Yu, Fang, Zhou, Haifeng, Lu, Huilin, Li, Qian, Deng, Zhiming

“…Few studies have compared the correlation between visceral fat area (VFA) and abdominal subcutaneous fat area (SFA) with arterial stiffness (AS) in patients…”
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Metabolic syndrome associated with higher glycemic variability in type 1 diabetes: A multicenter cross-sectional study in china by Guo, Keyu, Zhang, Liyin, Ye, Jianan, Niu, Xiaohong, Jiang, Hongwei, Gan, Shenglian, Zhou, Jian, Yang, Lin, Zhou, Zhiguang

“…Aims The comorbidity of metabolic syndrome (MetS) and type 1 diabetes mellitus (T1DM) is an obstacle to glucose control in patients with T1DM. We compared…”
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Positive correlation between lipid accumulation product index and arterial stiffness in Chinese patients with type 2 diabetes by Mao, Jing, Gan, Shenglian, Zhou, Quan, Yu, Fang, Zhou, Haifeng, Lu, Huilin, Jin, Jing, Liu, Qin, Deng, Zhiming

“…Many studies have confirmed that lipid accumulation products (LAP) predict arterial stiffness (AS) in hypertensive patients. But there is little research on…”
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Plasma atherogenicity index is a powerful indicator for identifying metabolic syndrome in adults with type 2 diabetes mellitus: A cross-sectional study by Gong, Shijun, Jin, Jing, Mao, Jing, Li, Heng, Mo, YePing, Zhou, Quan, Gan, Shenglian

“…Metabolic syndrome (MetS) is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). Elevated triglyceride (TG) levels and decreased…”
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AST/ALT ratio is an independent risk factor for diabetic retinopathy: A cross-sectional study by Luo, Jian, Yu, Fang, Zhou, Haifeng, Wu, Xueyan, Zhou, Quan, Liu, Qin, Gan, Shenglian

“…The aspartate to alanine transaminase (AST/ALT) ratio indicates oxidative stress and inflammatory reactions related to the occurrence of diabetic retinopathy…”
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INSR novel mutations identified in a Chinese family with severe INSR-related insulin resistance syndromes: A case report by Yu, Lu, Yu, Fang, Ma, Zongrui, Lu, Huilin, Luo, Jian, Sun, Ting, Liu, Qin, Gan, Shenglian

“…Severe insulin receptor gene (INSR)-related insulin resistance syndromes (SIR) include Donohue syndrome (DS), Rabson-Mendenhall syndrome (RMS), and type A…”
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Recurrent pancreatitis and sepsis in glycogen storage disease type Ia caused by complex heterozygous mutations in 2 sisters: Case report by Liu, Qin, Yu, Fang, Lu, Huilin, Luo, Jian, Sun, Ting, Yu, Lu, Gan, Shenglian

“…Glycogen storage disease (GSD) is a glycogen metabolism disorder caused by congenital enzyme defects, with type I being the most common. Owing to the rarity of…”
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115-LB: Dorzagliatin Showed Sustained Remission in an Observational Study after Discontinuation of Treatment in T2D Patients Who Achieved Good Glycemic Control with Dorzagliatin Monotherapy by ZENG, JIAOE, GAN, SHENGLIAN, DONG, XIAOLIN, LIU, YUNFENG, SU, XIAOFEI, LUO, JIANFENG, MA, JIANHUA

“…Diabetes remission is the optimal goal for treating T2D. While most remission studies focused on metabolic surgery, lifestyle interventions, and intensive…”
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847-P: Berberine Ursodeoxycholate (HTD1801) Improves Key Glycemic and Cardiometabolic Parameters across the Type 2 Diabetes Mellitus Disease Spectrum by Ji, Linong, Ma, Jianhua, Ma, Yujin, Cheng, Zhifeng, Gan, Shenglian, Yuan, Guoyue, Liu, Dexue, Li, Sheli, Liu, Yu, Xue, Xia, Bai, Jie, Wang, Kun, Cai, Hanqing, Li, Shu, Liu, Kui, Yu, Meng, Liu, Liping

“…Introduction: HTD1801 is a gut-liver anti-inflammatory metabolic modulator shown to improve key glycemic and cardiometabolic parameters. The aim of this study…”
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Efficacy and Safety of Mazdutide in Chinese Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial by Zhang, Bo, Cheng, Zhifeng, Chen, Ji, Zhang, Xin, Liu, Dexue, Jiang, Hongwei, Ma, Guoqing, Wang, Xiaoyun, Gan, Shenglian, Sun, Juan, Jin, Ping, Yi, Jianjun, Shi, Bimin, Ma, Jianhua, Ye, Shandong, Wang, Guixia, Ji, Linong, Gu, Xuejiang, Yu, Ting, An, Pei, Deng, Huan, Li, Haoyu, Li, Li, Ma, Qingyang, Qian, Lei, Yang, Wenying

“…We conducted a randomized, double-blind, placebo-controlled phase 2 trial to evaluate the efficacy and safety of mazdutide, a once-weekly glucagon-like peptide…”
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Inside Front Cover by Zeng, Jiao'e, Gan, Shenglian, Mi, Nianrong, Liu, Yunfeng, Su, Xiaofei, Zhang, Wenli, Zhang, Juan, Yu, Fang, Dong, Xiaolin, Han, Minmin, Luo, Jianfeng, Zhang, Yi, Chen, Li, Ma, Jianhua

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Diabetes remission in drug‐naïve patients with type 2 diabetes after dorzagliatin treatment: A prospective cohort study by Zeng, Jiao'e, Gan, Shenglian, Mi, Nianrong, Liu, Yunfeng, Su, Xiaofei, Zhang, Wenli, Zhang, Juan, Yu, Fang, Dong, Xiaolin, Han, Minmin, Luo, Jianfeng, Zhang, Yi, Chen, Li, Ma, Jianhua

“…Aim To investigate the post‐treatment effect of dorzagliatin in drug‐naïve patients with type 2 diabetes (T2D) regarding the achievement of stable glycaemic…”
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Dorzagliatin add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial by Yang, Wenying, Zhu, Dalong, Gan, Shenglian, Dong, Xiaolin, Su, Junping, Li, Wenhui, Jiang, Hongwei, Zhao, Wenjuan, Yao, Minxiu, Song, Weihong, Lu, Yibing, Zhang, Xiuzhen, Li, Huifang, Wang, Guixia, Qiu, Wei, Yuan, Guoyue, Ma, Jianhua, Li, Wei, Li, Ziling, Wang, Xiaoyue, Zeng, Jiao’e, Yang, Zhou, Liu, Jingdong, Liang, Yongqian, Lu, Song, Zhang, Huili, Liu, Hui, Liu, Ping, Fan, Kuanlu, Jiang, Xiaozhen, Li, Yufeng, Su, Qing, Ning, Tao, Tan, Huiwen, An, Zhenmei, Jiang, Zhaoshun, Liu, Lijun, Zhou, Zunhai, Zhang, Qiu, Li, Xuefeng, Shan, Zhongyan, Xue, Yaoming, Mao, Hong, Shi, Lixin, Ye, Shandong, Zhang, Xiaomei, Sun, Jiao, Li, Ping, Yang, Tao, Li, Feng, Lin, Jingna, Zhang, Zhinong, Zhao, Ying, Li, Ruonan, Guo, Xiaohui, Yao, Qi, Lu, Weiping, Qu, Shen, Li, Hongmei, Tan, Liling, Wang, Wenbo, Yao, Yongli, Chen, Daoxiong, Li, Yulan, Gao, Jialin, Hu, Wen, Fei, Xiaoqiang, Wu, Tianfeng, Dong, Song, Jin, Wenlong, Li, Chenzhong, Zhao, Dong, Feng, Bo, Zhao, Yu, Zhang, Yi, Li, Xiaoying, Chen, Li

“…Metformin, the first-line therapy for type 2 diabetes (T2D), decreases hepatic glucose production and reduces fasting plasma glucose levels. Dorzagliatin, a…”
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Dorzagliatin monotherapy in Chinese patients with type 2 diabetes: a dose-ranging, randomised, double-blind, placebo-controlled, phase 2 study by Zhu, Dalong, Gan, Shenglian, Liu, Yu, Ma, Jianhua, Dong, Xiaolin, Song, Weihong, Zeng, Jiao'e, Wang, Guixia, Zhao, Wenjuan, Zhang, Qiu, Li, Yukun, Fang, Hui, Lv, Xiaofeng, Shi, Yongquan, Tian, Haoming, Ji, Linong, Gao, Xin, Zhang, Lihui, Bao, Yuqian, Lei, Minxiang, Li, Ling, Zeng, Longyi, Li, Xiaoying, Hou, Xinghua, Zhao, Yu, Hu, Tianxin, Ge, Xiaoyun, Zhao, Guiyu, Li, Yongguo, Zhang, Yi, Chen, Li

“…Glucokinase acts as a glucose sensor in the pancreas and a glucose processor in the liver, and has a central role in glucose homoeostasis. Dorzagliatin is a…”
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Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study by Yu, Fang, Liu, Aizhong, Deng, Zhiming, Gan, Shenglian, Zhou, Quan, Long, Haowen

“…To explore the correlation between Chinese visceral adipose index (CVAI) and urinary microalbumin/creatinine ratio (UACR) and urinary albumin, and whether…”
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Optimal Anthropometric Indicators and Cut Points for Predicting Metabolic Syndrome in Chinese Patients with Type 2 Diabetes Mellitus by Gender by Mao, Jing, Gan, Shenglian, Zhou, Quan, Zhou, Haifeng, Deng, Zhiming

“…The best predictors and cut points for metabolic syndrome (MetS) in Chinese patients with type 2 diabetes (T2DM) were determined by comparing six…”
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