Search Results - "Gan, Huoqun"

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  1. 1

    B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids by Sanchez, Helia N., Moroney, Justin B., Gan, Huoqun, Shen, Tian, Im, John L., Li, Tianbao, Taylor, Julia R., Zan, Hong, Casali, Paolo

    Published in Nature communications (02-01-2020)
    “…Short-chain fatty acids (SCFAs) butyrate and propionate are metabolites from dietary fiber's fermentation by gut microbiota that can affect differentiation or…”
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    Journal Article
  2. 2

    B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response by Gan, Huoqun, Shen, Tian, Chupp, Daniel P, Taylor, Julia R, Sanchez, Helia N, Li, Xin, Xu, Zhenming, Zan, Hong, Casali, Paolo

    Published in Science advances (01-04-2020)
    “…Activation-induced cytidine deaminase (AID) mediates immunoglobulin class switch DNA recombination (CSR) and somatic hypermutation (SHM), critical processes…”
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    Journal Article
  3. 3

    Sirt1-mediated metabolic modulation of Aicda , class-switch DNA recombination and somatic hypermutation by Gan, Huoqun, shen, Tian, Sanchez, Helia, Xu, Zhenming, Zan, Hong, Casali, Paolo

    Published in The Journal of immunology (1950) (01-05-2018)
    “…Abstract Maturation of the antibody response entails Ig somatic hypermutation (SHM) and class switch DNA recombination (CSR). SHM and CSR perfect the…”
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    Journal Article
  4. 4

    Sirt1 modulates immunoglobulin class switch DNA recombination and somatic hypermutation by regulating B lymphocyte Aicda expression through NF-kB deacetylation by Gan, Huoqun, shen, Tian, Sanchez, Helia N., Vasudev, Anusha, Taylor, Julia R., Zan, Hong, Casali, Paolo

    Published in The Journal of immunology (1950) (01-05-2017)
    “…Abstract Maturation of the antibody response entails Ig class switch DNA recombination (CSR) and somatic hypermutation (SHM), which perfect the antigen-binding…”
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    Journal Article
  5. 5

    B cell-intrinsic epigenetic modulation of local and systemic antibody response by gut microbiota through catabolic short-chain fatty acids by Sanchez, Helia N., Gan, Huoqun, Moroney, Justin B., Daw, Cassidy C., Taylor, Julia, Zan, Hong, Casali, Paolo

    Published in The Journal of immunology (1950) (01-05-2018)
    “…Abstract Immunoglobulin class switch DNA recombination (CSR) and somatic hypermutation (SHM), as initiated by AID, and plasma cell differentiation, as mediated…”
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    Journal Article
  6. 6

    B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching by Yan, Hui, Fernandez, Maria, Wang, Jingwei, Wu, Shuai, Wang, Rui, Lou, Zheng, Moroney, Justin B, Rivera, Carlos E, Taylor, Julia R, Gan, Huoqun, Zan, Hong, Kolvaskyy, Dmytro, Liu, Dongfang, Casali, Paolo, Xu, Zhenming

    Published in The Journal of immunology (1950) (01-03-2020)
    “…Upon activation by CD40 or TLR signaling, B lymphocytes activate NF-κB to induce activation-induced cytidine deaminase and, therefore, Ig class switch DNA…”
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  7. 7