Search Results - "Gan, Dakai"
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Ursolic acid ameliorates CCl4‐induced liver fibrosis through the NOXs/ROS pathway
Published in Journal of cellular physiology (01-10-2018)“…Liver fibrosis is a reversible wound‐healing response that occurs after liver injury. NADPH oxidases (NOXs) and reactive oxygen species (ROS) which are…”
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The impact of artificial liver support system on intestinal microbiota and serum bile acid profiles in patients with acute-on-chronic liver failure: a prospective cohort study
Published in Hepatology international (01-10-2024)“…Background Acute-on-chronic liver failure (ACLF) patients exhibit an imbalance in intestinal microbiota, and bile acids (BAs) can affect the composition of…”
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Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells
Published in Frontiers in pharmacology (2019)“…Studies have shown that both NOX4 and RhoA play essential roles in fibrosis and that they regulate each other. In lung fibrosis, NOX4/ROS is located upstream…”
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Protective Effect of Ursolic Acid on the Intestinal Mucosal Barrier in a Rat Model of Liver Fibrosis
Published in Frontiers in physiology (30-07-2019)“…Oxidative stress mediated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) plays an important role in intestinal mucosal barrier damage in…”
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Development of a novel prognostic assessment model for hepatitis B virus-related acute-on-chronic liver failure based on reexamination results
Published in Medicine (Baltimore) (17-03-2023)“…Acute-on-chronic liver failure (ACLF) is a common clinical emergency and critical illness with rapid progression and poor prognosis. This study aims to…”
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