Search Results - "Gams, Anna"
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Evidence of Superior and Inferior Sinoatrial Nodes in the Mammalian Heart
Published in JACC. Clinical electrophysiology (01-12-2020)“…This study sought to investigate the shift of leading pacemaker locations in healthy and failing mammalian hearts over the entire range of physiological heart…”
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2
Genetic algorithm-based personalized models of human cardiac action potential
Published in PloS one (11-05-2020)“…We present a novel modification of genetic algorithm (GA) which determines personalized parameters of cardiomyocyte electrophysiology model based on set of…”
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3
Correction: Genetic algorithm-based personalized models of human cardiac action potential
Published in PloS one (22-12-2020)“…[This corrects the article DOI: 10.1371/journal.pone.0231695.]…”
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Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane
Published in Frontiers in physiology (21-01-2021)“…Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP…”
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5
Evidence of sex differences in cancer‐related cardiac complications in mouse models of pancreatic and liver cancer
Published in Physiological reports (01-04-2023)“…Abnormal heart rate variability (HRV) is commonly observed in cancer patients who have undergone targeted therapy and/or surgery, yet the effects of cancer…”
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The Role of Genome Regulatory Network in Sex Dimorphism of Cardiac Health, Disease, and Aging
Published 01-01-2023“…The prevalence of cardiovascular diseases differs between men and women. For example, men are more likely to develop hypertrophic and dilated cardiomyopathies,…”
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Dissertation -
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Abstract 12468: Atlas of Human Cardiac Promoters Reveals Regulatory Shift Between Healthy and Failing States
Published in Circulation (New York, N.Y.) (16-11-2021)“…IntroductionGenome regulatory elements capture transcription networks across diverse biological states. We aimed to identify and compare active promoter…”
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Human Organotypic Cardiac Slices: A Platform to Study Major Potassium Channels Contribution and Modulation of Human Cardiac Repolarization
Published in Biophysical journal (07-02-2020)Get full text
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9
B-PO03-025 AUTONOMIC MODULATION OF HUMAN RIGHT VENTRICULAR OUTFLOW TRACT: IMPLICATIONS FOR ARRHYTHMOGENESIS
Published in Heart rhythm (01-08-2021)Get full text
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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network
Published in Circulation (New York, N.Y.) (09-04-2024)“…The relationship between heart failure (HF) and atrial fibrillation (AF) is clear, with up to half of patients with HF progressing to AF. The…”
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11
Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity
Published in Toxicology and applied pharmacology (01-11-2020)“…The limited availability of human heart tissue and its complex cell composition are major limiting factors for the reliable testing of drug efficacy and…”
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Electrophysiology and Arrhythmogenesis in the Human Right Ventricular Outflow Tract
Published in Circulation. Arrhythmia and electrophysiology (01-03-2022)“…Right ventricular outflow tract (RVOT) is a common source of ventricular tachycardia, which often requires ablation. However, the mechanisms underlying the…”
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13
Molecular and Functional Remodeling of Superior and Inferior SAN in a Rat Model of HCM
Published in JACC. Clinical electrophysiology (01-11-2022)“…Recently, our laboratory presented functional and molecular evidence for the presence of 2 competing sinoatrial node (SAN) pacemakers in healthy human and rat…”
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14
Electrophysiology and Arrhythmogenesis in the Human Right Ventricular Outflow Tract
Published in Circulation. Arrhythmia and electrophysiology (04-03-2022)Get full text
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Electrophysiology and Arrhythmogenesis in the Human Right Ventricle Outflow Tract
Published in Circulation. Arrhythmia and electrophysiology (01-03-2022)Get full text
Journal Article