Search Results - "Gamez, Graciela"

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    Metastatic cells are preferentially vulnerable to lysosomal inhibition by Morgan, Michael J., Fitzwalter, Brent E., Owens, Charles R., Powers, Rani K., Sottnik, Joseph L., Gamez, Graciela, Costello, James C., Theodorescu, Dan, Thorburn, Andrew

    “…Molecular alterations that confer phenotypic advantages to tumors can also expose specific therapeutic vulnerabilities. To search for potential treatments that…”
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    Journal Article
  2. 2

    Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent by Morgan, Michael J, Gamez, Graciela, Menke, Christina, Hernandez, Ariel, Thorburn, Jacqueline, Gidan, Freddi, Staskiewicz, Leah, Morgan, Shellie, Cummings, Christopher, Maycotte, Paola, Thorburn, Andrew

    Published in Autophagy (01-10-2014)
    “…Chloroquine (CQ) is an antimalarial drug and late-stage inhibitor of autophagy currently FDA-approved for use in the treatment of rheumatoid arthritis and…”
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  3. 3

    RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis by Yonekawa, Tohru, Gamez, Graciela, Kim, Jihye, Tan, Aik Choon, Thorburn, Jackie, Gump, Jacob, Thorburn, Andrew, Morgan, Michael J

    Published in EMBO reports (01-06-2015)
    “…In a synthetic lethality/viability screen, we identified the serine–threonine kinase RIP1 (RIPK1) as a gene whose knockdown is highly selected against during…”
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    Journal Article
  4. 4

    Mitochondrially Mediated Integrin αIIbβ3 Protein Inactivation Limits Thrombus Growth by Liu, Fang, Gamez, Graciela, Myers, David R., Clemmons, Wayne, Lam, Wilbur A., Jobe, Shawn M.

    Published in The Journal of biological chemistry (18-10-2013)
    “…When platelets are strongly stimulated, a procoagulant platelet subpopulation is formed that is characterized by phosphatidylserine (PS) exposure and epitope…”
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  5. 5

    Anti-Inositolglycan Antibodies Selectively Block Some of the Actions of Insulin in Intact BC3H1 Cells by Romero, Guillermo, Gamez, Graciela, Huang, Laura C., Lilley, Kevin, Luttrell, Louis

    “…We have studied the mechanism of generation of insulin mediators by using specific antibodies raised against the oligosaccharide anchor of membrane proteins…”
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    Human Immunodeficiency Virus Type 1 Pathogenesis in SCID-hu Mice Correlates with Syncytium-Inducing Phenotype and Viral Replication by Camerini, D, Su, H P, Gamez-Torre, G, Johnson, M L, Zack, J A, Chen, I S

    Published in Journal of Virology (01-04-2000)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Mitochondrially-Mediated Platelet Integrin AlphaIIbbeta3 Inactivation Limits Platelet Recruitment and Thrombus Growth by Liu, Fang, Gamez, Graciela, Myers, David R, Lam, Wilbur, Jobe, Shawn M

    Published in Blood (18-11-2011)
    “…Abstract 3251 Platelet stimulation with strong agonist(s) results in the formation of a phenotypically unique platelet subpopulation known as procoagulant…”
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