Search Results - "Gameel, A"

A new exploration toward adamantane derivatives as potential anti‐MDR agents: Design, synthesis, antimicrobial, and radiosterilization activity as potential topoisomerase IV and DNA gyrase inhibitors by Ragab, Ahmed, Abusaif, Moustafa S., Aboul‐Magd, Dina S., Wassel, Mohammed M. S., Elhagali, Gameel A. M., Ammar, Yousry A.

“…Developing novel antimicrobial agents has become a necessitate due to the increasing rate of microbial resistance to antibiotics. All the newly adamantane…”
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Synthesis, characterization, and in vitro antibacterial activity of some new pyridinone and pyrazole derivatives with some in silico ADME and molecular modeling study by Saadon, Khadija E., Taha, Nadia M. H., Mahmoud, N. A., Elhagali, Gameel A. M., Ragab, Ahmed

“…A new series of pyridine-2-one and pyrazole derivatives were designed and synthesized based on cyanoacrylamide derivatives containing 2,4-dichlro aniline and…”
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Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR by Wassel, Mohammed M.S., Ammar, Yousry A., Elhag Ali, Gameel A.M., Belal, Amany, Mehany, Ahmed B.M., Ragab, Ahmed

“…Plausible targets and the obtained results for the most promising three adamantane derivatives 5, 14c and 17 and Erlotinib. [Display omitted] •New…”
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Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers by El-Sharief, Ahmed M. Sh, Ammar, Yousry A., Belal, Amany, El-Sharief, Marwa A.M. Sh, Mohamed, Yehia A., Mehany, Ahmed B.M., Elhag Ali, Gameel A.M., Ragab, Ahmed

“…[Display omitted] •A novel series of indole derivatives were designed and synthesized.•Anticancer activity evaluation of the new compounds was performed using…”
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Utilising UPLC-QTOF-MS/MS to determine the phytochemical profile and in vitro cytotoxic potential of Ziziphora capitata L. with molecular docking simulation by Youssif, Youssif M, Elhagali, Gameel A M, Zahran, Medhat A, Ahmed, Fatma A, Ragab, Ahmed

“…(Lamiaceae family) aerial parts extract contains 57 metabolites, including flavonoids, phenolic acids, anthocyanins, and coumarins, as assessed by…”
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Mycobacterium avium subsp. paratuberculosis and microbiome profile of patients in a referral gastrointestinal diseases centre in the Sudan by Elmagzoub, Wisal A, Idris, Sanaa M, Isameldin, Maha, Arabi, Nassir, Abdo, Abdelmonem, Ibrahim, Mustafa, Khan, Md Anik Ashfaq, Tanneberger, Franziska, Bakhiet, Sahar M, Okuni, Julius B, Ojok, Lonzy, Gameel, Ahmed A, Abd El Wahed, Ahmed, Bekaert, Michaël, Mukhtar, Mohamed E, Amanzada, Ahmad, Eltom, Kamal H, Eltayeb, ElSagad

“…Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease in animals with zoonotic potential; it has been linked to many chronic diseases in…”
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Hybridized Quinoline Derivatives as Anticancer Agents: Design, Synthesis, Biological Evaluation and Molecular Docking by Selim, Mohamed R, Zahran, Medhat A, Belal, Amany, Abusaif, Moustafa S, Shedid, Said A, Mehany, Ahmed B M, Elhagali, Gameel A M, Ammar, Yousry A

“…Conjugating quinolones with different bioactive pharmacophores to obtain potent anticancer active agents. Fused pyrazolopyrimidoquinolines 3a-d, Schiff bases…”
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Applying UPLC-QTOF-MS/MS to profile the phytochemical constituents associated with docking studies of major components of Ziziphora capitata L as well as antimicrobial and antioxidant activity assessments of its subsequent fractions by Youssif, Youssif M., Ragab, Ahmed, Zahran, Medhat A., Ahmed, Fatma A., Elhagali, Gameel A. M.

“…This study aimed to investigate the phytochemical constituents, antimicrobial activity, and antioxidant effects of successive extracts of Ziziphora capitata L…”
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Characterization of the complete genomes of Camelus dromedarius papillomavirus types 1 and 2 by URE, A. E, ELFADL, A. K, KHALAFALLA, A. I, GAMEEL, A. A. R, DILLNER, J, FORSLUND, O

“…Camel papillomatosis has been described previously, but the genome of the suspected papillomavirus (PV) has not been identified. An outbreak of papillomatosis…”
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First report and molecular characterization of Cryptosporidium spp. in humans and animals in Khartoum state, Sudan by Adam, Kaltoum Yagoub, Ismail, A A, Masri, M A, Gameel, A A

“…is recognized to infect several mammalian species as well as humans, causing substantial economic losses and serious public health concern. Infected animals…”
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Cu(II)-Promoted the Chemical Synthesis of New Azines-Based Naphthalene Scaffold as In Vitro Potent Mushroom Tyrosinase Inhibitors and Evaluation of Their Antiproliferative Activity by Eliwa, Essam M., Elgammal, Walid E., Belal, Amany, Abourehab, Mohammed A. S., Abd El-Gilil, Shimaa M., Mehany, Ahmed B. M., Elhagali, Gameel A. M.

“…Herein, synthesis of new designated azines-based naphthalene scaffold (3a-10) was assisted by CuCl 2 .2H 2 O for the first time. Their biological screening…”
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First Report on Ovine Paratuberculosis in the Sudan: Diagnosis Using Different Techniques by Idris, Sanaa M, Ali, Eva A, Elmagzoub, Wisal A, Okuni, Julius B, Mukhtar, Mohamed E, Ojok, Lonzy, Eltayeb, ElSagad, Abd El Wahed, Ahmed, Eltom, Kamal H, Gameel, Ahmed A

“…Paratuberculosis (PTB) has been reported in the Sudan in cattle and goats for more than 50 years but has never been reported in sheep. However, suspicion of…”
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Paratuberculosis: The Hidden Killer of Small Ruminants by Idris, Sanaa M, Eltom, Kamal H, Okuni, Julius B, Ojok, Lonzy, Elmagzoub, Wisal A, El Wahed, Ahmed Abd, Eltayeb, ElSagad, Gameel, Ahmed A

“…Paratuberculosis (PTB) is a contagious and chronic enteric disease of ruminants and many non-ruminants caused by subsp. (MAP), and is characterised by…”
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Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4′-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones by El-Gaby, Mohamed S.A., El-Hag Ali, Gameel A.M., El-Maghraby, Ahmed A., Abd El-Rahman, Mohamed T., Helal, Mohamed H.M.

“…2-Thioxo-4-thiazolidinones ( 3a, b) were achieved by cyclocondensation of isothiocyanatosulfonamides ( 1a, b) with sulfanylacetic acid at reflux temperature in…”
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Seroprevalence of Mycobacterium avium subsp. paratuberculosis in Dairy Cattle in Khartoum State, Sudan by Elmagzoub, Wisal A, Adam, Nabawia M, Idris, Sanaa M, Mukhtar, Mohamed E, Abdelaziz, Sanaa A, Okuni, Julius B, Ojok, Lonzy, Abd El Wahed, Ahmed, Eltayeb, ElSagad, Gameel, Ahmed A, Eltom, Kamal H

“…Paratuberculosis, caused by subspecies (MAP), is a chronic wasting disease mainly of domestic and wild ruminants. It occurs worldwide, causing significant…”
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Chemistry of 2-cyanomethylene-4-thiazolidinone by El-Gaby, Mohamed S. A., Ammar, Yousry A., El-Hag Ali, Gameel A. M., Helal, Mohamed H. M., Salem, Mohamed A., Ghorab, Mostafa M.

“…This article is a brief review about the synthesis and chemistry of 2-cyanomethylene-4-thiazolidinone 1. The most significant applications of 4-thiazolidinone…”
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Molecular and in-silico analysis of single nucleotide polymorphism targeting human TP53 gene exon 5-8 in Sudanese esophageal cancer patients [version 1; peer review: 2 approved, 1 approved with reservations] by Elfaki, Rihab M, Abdelaziz, Mohammed S, Altayb, Hisham N, Munsoor, Munsoor M, Gameel, Ahmed A

“…Background: The protein product of the normal TP53 gene performs an essential function in cell cycle control and tumor suppression, and the mutation of a TP53…”
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Traditional medicinal plants indigenous to Al-Rass province, Saudi Arabia by Gamal, E El Ghazali, Khalifa, S Al Khalifa, Gameel, A Saleem, Emad, M Abdallah

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In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens by Ali Mohamed, Hazem, Ammar, Yousry A, A M Elhagali, Gameel, A Eyada, Hassan, S Aboul-Magd, Dina, Ragab, Ahmed

“…A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically attractive cores were initially synthesized using a hybridization…”
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Identification of cattle persistently infected with BVDV by ear-notch testing in Saudi Arabia by Al-Khaliyfa, M. A., Abuelzein, E. M. E., Gameel, A. A.

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