Search Results - "Game, Bryan A."

High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor κB and AP-1 activities by Nareika, Alena, Im, Yeong-Bin, Game, Bryan A, Slate, Elizabeth H, Sanders, John J, London, Steven D, Lopes-Virella, Maria F, Huang, Yan

“…We have demonstrated recently that high glucose augments lipopolysaccharide (LPS)-stimulated matrix metalloproteinase (MMP) and cytokine expression by U937…”
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Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice by Game, Bryan A, He, Lin, Jarido, Veronica, Nareika, Alena, Jaffa, Ayad A, Lopes-Virella, Maria F, Huang, Yan

“…Abstract Connective tissue growth factor (CTGF) is expressed in atherosclerotic plaques. It is generally recognized that CTGF contributes to atherosclerosis by…”
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Administration of Pioglitazone in Low-Density Lipoprotein Receptor-Deficient Mice Inhibits Lesion Progression and Matrix Metalloproteinase Expression in Advanced Atherosclerotic Plaques by He, Lin, Game, Bryan A, Nareika, Alena, Garvey, W Timothy, Huang, Yan

“…Recent clinical trials have provided evidence that pioglitazone reduces cardiovascular events in patients with type 2 diabetes. However, the underlying…”
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C-Reactive Protein Stimulates MMP-1 Expression in U937 Histiocytes Through FcγRII and Extracellular Signal-Regulated Kinase Pathway:: An Implication of CRP Involvement in Plaque Destabilization by Williams, Takeyla N, Zhang, Cecelia X, Game, Bryan A, He, Lin, Huang, Yan

“…OBJECTIVE—It has been shown that plasma level of C-reactive protein (CRP) is an independent predictor for acute coronary syndromes and is associated with…”
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High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity by Nareika, Alena, Sundararaj, Kamala P, Im, Yeong-Bin, Game, Bryan A, Lopes-Virella, Maria F, Huang, Yan

“…Abstract Recent diabetes control and complications trial and epidemiology of diabetes interventions and complications (DCCT/EDIC) and other clinical studies…”
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Pioglitazone inhibits MMP-1 expression in vascular smooth muscle cells through a mitogen-activated protein kinase-independent mechanism by Game, Bryan A., Maldonado, Alejandro, He, Lin, Huang, Yan

“…Antidiabetic drug thiazolidinedione (TZD) also has anti-atherogenic effects. Among these effects, inhibition of smooth muscle cell (SMC) migration is…”
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Pre-exposure to high glucose augments lipopolysaccharide-stimulated matrix metalloproteinase-1 expression by human U937 histiocytes by Maldonado, Alejandro, He, Lin, Game, Bryan A., Nareika, Alena, Sanders, John J., London, Steve D, Lopes-Virella, Maria F., Huang, Yan

“…Background and objectives:  It has been well established that patients with diabetes have increased prevalence and severity of periodontal diseases. However,…”
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Up‐regulation of matrix metalloproteinase‐1 expression in U937 cells by low‐density lipoprotein‐containing immune complexes requires the activator protein‐1 and the Ets motifs in the distal and the proximal promoter regions by Maldonado, Alejandro, Game, Bryan A., Song, Lanxi, Huang, Yan

“…Summary We reported previously that low‐density lipoprotein (LDL)‐containing immune complexes (LDL‐IC) stimulated matrix metalloproteinase‐1 (MMP‐1) expression…”
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Regulation of MMP-1 expression in vascular endothelial cells by insulin sensitizing thiazolidinediones by Game, Bryan A., Xu, Minfu, Lopes-Virella, Maria F., Huang, Yan

“…Matrix metalloproteinases (MMPs) have been implicated in the disruption of atherosclerotic plaques that leads to acute coronary events. The present study…”
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IFN-γ Pretreatment Augments Immune Complex-Induced Matrix Metalloproteinase-1 Expression in U937 Histiocytes by Anderson, Fran, Game, Bryan A., Atchley, Dan, Xu, Minfu, Lopes-Virella, Maria F., Huang, Yan

“…We reported recently that immune complexes (ICs) induced matrix metalloproteinase-1 (MMP-1) expression in U937 histiocytes. The present study was undertaken to…”
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Pioglitazone Inhibits Connective Tissue Growth Factor Expression during the Progression of Aortic Atherosclerotic Plaques in LDL Receptor-Deficient Mice by Game, Bryan A, He, Lin, Jarido, Veronica, Jaffa, Ayad A

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Sodium Lactate and Lipopolysaccharide Exert Synergistic Effect on MMP and Cytokine Expression in U937 Histiocytes through NF[kappa]B and MAPK Pathways by Nareika, Alena, He, Lin, Game, Bryan A, Sanders, John J

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Administration of Pioglitazone to LDL Receptor-Deficient Mice Inhibits Progression of Intimal Lesions and Expression of Matrix Metalloproteinases and Adhesion Molecules by He, Lin, Game, Bryan A, Garvey, W Timothy, Huang, Yan

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High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor KB and AP-1 activities by NAREIKA, Alena, IM, Yeong-Bin, GAME, Bryan A, SLATE, Elizabeth H, SANDERS, John J, LONDON, Steven D, LOPES-VIRELLA, Maria F, YAN HUANG

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Up-regulation of matrix metalloproteinase-1 expression in U937 cells by low-density lipoprotein-containing immune complexes requires the activator protein-1 and the by Maldonado, Alejandro, Game, Bryan A, Song, Lanxi, Huang, Yan

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Sodium lactate increases LPS-stimulated MMP and cytokine expression in U937 histiocytes by enhancing AP-1 and NF-kappaB transcriptional activities by Nareika, Alena, He, Lin, Game, Bryan A, Slate, Elizabeth H, Sanders, John J, London, Steven D, Lopes-Virella, Maria F, Huang, Yan

“…The plasma lactate concentration in patients with obesity and type 2 diabetes is often higher than that in nondiabetic individuals. Although it is known that…”
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C-reactive protein stimulates MMP-1 expression in U937 histiocytes through Fc[gamma]RII and extracellular signal-regulated kinase pathway:: an implication of CRP involvement in plaque destabilization by Williams, Takeyla N, Zhang, Cecelia X, Game, Bryan A, He, Lin, Huang, Yan

“…It has been shown that plasma level of C-reactive protein (CRP) is an independent predictor for acute coronary syndromes and is associated with plaque…”
Get full text

High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities by Nareika, Alena, Im, Yeong-Bin, Game, Bryan A, Slate, Elizabeth H, Sanders, John J, London, Steven D, Lopes-Virella, Maria F, Huang, Yan

“…We have demonstrated recently that high glucose augments lipopolysaccharide (LPS)-stimulated matrix metalloproteinase (MMP) and cytokine expression by U937…”
Get full text