Search Results - "Gamain, B."
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TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood
Published in Scientific reports (19-09-2016)“…After invading red blood cells (RBCs), Plasmodium falciparum ( Pf ) can export its own proteins to the host membrane and activate endogenous channels that are…”
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2
Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals
Published in Cell host & microbe (13-12-2023)“…The erythrocyte silent Duffy blood group phenotype in Africans is thought to confer resistance to Plasmodium vivax blood-stage infection. However, recent…”
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3
Increase in glutathione peroxidase activity in malaria parasite after selenium supplementation
Published in Free radical biology & medicine (1996)“…Glutathione peroxidase (GPx), a key enzyme involved in the detoxification of many peroxides, has been investigated in two malaria parasite species: P. yoelii…”
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The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2017)“…Multiple sclerosis (MS) is a severe autoimmune disease characterized by inflammatory, demyelinating and neurodegenerative components causing motor, sensory,…”
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Molecular characterization of the glutathione peroxidase gene of the human malaria parasite Plasmodium falciparum
Published in Molecular and biochemical parasitology (01-06-1996)“…In this paper we report the isolation and the characterization of a gene encoding the antioxidant enzyme glutathione peroxidase from the human malaria parasite…”
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A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A
Published in EMBO reports (01-08-2005)“…In high‐transmission regions, protective clinical immunity to Plasmodium falciparum develops during the early years of life, limiting serious complications of…”
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The course of Plasmodium berghei, P. chabaudi and P. yoelii infections in beta-thalassaemic mice
Published in Parasitology (01-03-1996)“…In order to study the effects of acclimatization of Plasmodium in beta-thalassaemic mice, we used a mouse model of beta-thalassaemia…”
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Identification of Multiple Chondroitin Sulfate A (CSA)–Binding Domains in the var2CSA Gene Transcribed in CSA-Binding Parasites
Published in The Journal of infectious diseases (15-03-2005)“…Malaria in pregnancy is a serious complication associated with parasitized erythrocyte (PE) sequestration in the placenta. Recent work suggests that var genes…”
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Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain
Published in Scientific reports (09-12-2014)“…VAR2CSA stands today as the leading vaccine candidate aiming to protect future pregnant women living in malaria endemic areas against the severe clinical…”
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Classification of adhesive domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 family
Published in Molecular and biochemical parasitology (01-10-2000)“…The Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) family of cytoadherent proteins has a central role in disease from malaria infection. This…”
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The Putative Glutathione Peroxidase Gene of Plasmodium falciparum Codes for a Thioredoxin Peroxidase
Published in The Journal of biological chemistry (09-03-2001)“…A putative glutathione peroxidase gene (Swiss-Prot accession number Z 68200) of Plasmodium falciparum , the causative agent of tropical malaria, was expressed…”
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Plasmodium falciparum Domain Mediating Adhesion to Chondroitin Sulfate A: A Receptor for Human Placental Infection
Published in Proceedings of the National Academy of Sciences - PNAS (26-10-1999)“…Malaria during the first pregnancy causes a high rate of fetal and neonatal death. The decreasing susceptibility during subsequent pregnancies correlates with…”
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Decoding the language of var genes and Plasmodium falciparum sequestration
Published in Trends in Parasitology (01-11-2001)“…Sequestration and rosetting are key determinants of Plasmodium falciparum pathogenesis. They are mediated by a large family of variant proteins called P…”
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Babesia hylomysci and B. divergens : presence of antioxidant enzymes destroying hydrogen peroxide
Published in Parasitology research (1987) (17-11-1997)Get full text
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Molecular Basis for the Dichotomy in Plasmodium falciparum Adhesion to CD36 and Chondroitin Sulfate A
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2002)“…Plasmodium falciparum-infected erythrocytes adhere dichotomously to the host receptors CD36 and chondroitin sulfate A (CSA). This dichotomy is associated with…”
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Identification of a 67‐amino‐acid region of the Plasmodium falciparum variant surface antigen that binds chondroitin sulphate A and elicits antibodies reactive with the surface of placental isolates
Published in Molecular microbiology (01-07-2004)“…Summary The complications of malaria in pregnancy are caused by the massive sequestration of parasitized erythrocytes (PE) in the placenta. Placental isolates…”
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Immunization of Aotus Monkeys with a Functional Domain of the Plasmodium falciparum Variant Antigen Induces Protection against a Lethal Parasite Line
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2002)“…Immunity to Plasmodium falciparum in African children has been correlated with antibodies to the P. falciparum erythrocyte membrane protein 1 (PfEMP1) variant…”
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The human placental derived BeWo cell line: A useful model for selecting Plasmodium falciparum CSA-binding parasites
Published in Experimental parasitology (01-02-2006)“…Chondroitin sulfate A (CSA) present in the placental intervillous blood spaces has been described as the main receptor involved in the massive sequestration of…”
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The Surface Variant Antigens of Plasmodium falciparum Contain Cross-Reactive Epitopes
Published in Proceedings of the National Academy of Sciences - PNAS (27-02-2001)“…Plasmodium falciparum parasites evade the host immune system by clonal expression of the variant antigen, P. falciparum erythrocyte membrane protein 1…”
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DNA Immunization with the Cysteine-Rich Interdomain Region 1 of the Plasmodium falciparum Variant Antigen Elicits Limited Cross-Reactive Antibody Responses
Published in Infection and Immunity (01-08-2003)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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