Search Results - "Galvez, Carlos Cabrera"
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Spatial profiling of METex14-altered NSCLC under tepotinib treatment: Shifting the immunosuppressive landscape
Published in Neoplasia (New York, N.Y.) (01-11-2024)“…•Tepotinib downstages NSCLC from IIIB to IA1 in a patient with a METex14 skipping alteration.•GeoMx spatial analysis reveals increased immune cell diversity…”
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Keynote 407: the combination of pembrolizumab and chemotherapy cracks the shell of squamous cell lung cancer
Published in Translational lung cancer research (01-06-2020)Get full text
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RNA-Based Multiplexing Assay for Routine Testing of Fusion and Splicing Variants in Cytological Samples of NSCLC Patients
Published in Diagnostics (Basel) (23-12-2020)“…The detection of ALK receptor tyrosine kinase (ALK), ROS proto-oncogen1, receptor tyrosine kinase (ROS1), ret proto-oncogen (RET), and MET proto-oncogen exon…”
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Clinical response to tepotinib according to circulating tumor (ct) DNA biomarkers in patients with advanced NSCLC with high-level MET amplification ( MET amp) detected by liquid biopsy (LBx)
Published in Journal of clinical oncology (01-06-2022)“…9121 Background: Tepotinib, a potent, highly selective, oral, MET inhibitor, showed meaningful activity in patients (pts) with NSCLC with high-level METamp by…”
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Tepotinib in patients (pts) with advanced non-small cell lung cancer (NSCLC) with MET amplification ( MET amp)
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 9021 Background: METamp is an oncogenic driver occurring in 1–5% of NSCLCs that confers a poor prognosis and lacks approved targeted therapies…”
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T-cell infiltration in matched samples from malignant pleural mesothelioma (MPM) during evolution of disease
Published in Journal of clinical oncology (01-06-2022)“…e20595 Background: MPM is an aggressive cancer associated with asbestos exposure. Chemotherapy has been a mainstay of therapy and recently immunotherapy has…”
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Tepotinib in patients with non-small cell lung cancer with high-level MET amplification detected by liquid biopsy: VISION Cohort B
Published in Cell reports. Medicine (21-11-2023)“…High-level MET amplification (METamp) is a primary driver in ∼1%-2% of non-small cell lung cancers (NSCLCs). Cohort B of the phase 2 VISION trial evaluates…”
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Abstract 2606: A nCounter-Based mRNA signature in plasma associates with localized non-small cell lung cancer
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Background: 80% of non-small cell lung cancer (NSCLC) cases are diagnosed at stages IIIB-IV and have a dismal prognosis with a median life expectancy that does…”
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