Search Results - "Galvão Ferrarini, Mariana"
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Hydrogen peroxide production and myo‐inositol metabolism as important traits for virulence of Mycoplasma hyopneumoniae
Published in Molecular microbiology (01-06-2018)“…Summary Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia. In our previous work, we reconstructed the metabolic models of this species…”
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2
MicroRNA Target Identification: Revisiting Accessibility and Seed Anchoring
Published in Genes (07-03-2023)“…By pairing to messenger RNAs (mRNAs for short), microRNAs (miRNAs) regulate gene expression in animals and plants. Accurately identifying which mRNAs interact…”
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A comprehensive evaluation of binning methods to recover human gut microbial species from a non-redundant reference gene catalog
Published in NAR genomics and bioinformatics (01-03-2021)“…Abstract The human gut microbiota performs functions that are essential for the maintenance of the host physiology. However, characterizing the functioning of…”
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4
Efficient compartmentalization in insect bacteriomes protects symbiotic bacteria from host immune system
Published in Microbiome (27-09-2022)“…Abstract Background Many insects house symbiotic intracellular bacteria (endosymbionts) that provide them with essential nutrients, thus promoting the usage of…”
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Endosymbiont-containing germarium transcriptional survey in a cereal weevil depicts downregulation of immune effectors at the onset of sexual maturity
Published in Frontiers in physiology (22-03-2023)“…Insects often establish long-term relationships with intracellular symbiotic bacteria, i.e., endosymbionts, that provide them with essential nutrients such as…”
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BrumiR: A toolkit for de novo discovery of microRNAs from sRNA-seq data
Published in Gigascience (25-10-2022)“…Abstract MicroRNAs (miRNAs) are small noncoding RNAs that are key players in the regulation of gene expression. In the past decade, with the increasing…”
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Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp
Published in Microbiome (13-12-2023)“…Insects living in nutritionally poor environments often establish long-term relationships with intracellular bacteria that supplement their diets and improve…”
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Totoro: Identifying Active Reactions During the Transient State for Metabolic Perturbations
Published in Frontiers in genetics (21-02-2022)“…The increasing availability of metabolomic data and their analysis are improving the understanding of cellular mechanisms and how biological systems respond to…”
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Modulation of Klebsiella pneumoniae Outer Membrane Vesicle Protein Cargo under Antibiotic Treatment
Published in Biomedicines (24-05-2023)“…is a nosocomial pathogen and an important propagator of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. Like other Gram-negative…”
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10
Transcriptomic-based selection of reference genes for quantitative real-time PCR in an insect endosymbiotic model
Published in Frontiers in ecology and evolution (20-04-2023)“…Reference genes are a fundamental tool for analyses of gene expression by real-time quantitative PCR (qRT-PCR), in that they ensure the correct comparison…”
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Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis
Published in mSphere (06-01-2021)“…Toxoplasmosis, a protozoan infection caused by , is estimated to affect around 2.5 billion people worldwide. Nevertheless, the side effects of drugs combined…”
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Spatial and morphological reorganization of endosymbiosis during metamorphosis accommodates adult metabolic requirements in a weevil
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2020)“…Bacterial intracellular symbiosis (endosymbiosis) is widespread in nature and impacts many biological processes. In holometabolous symbiotic insects,…”
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The transposable element-rich genome of the cereal pest Sitophilus oryzae
Published in BMC biology (09-11-2021)“…The rice weevil Sitophilus oryzae is one of the most important agricultural pests, causing extensive damage to cereal in fields and to stored grains. S. oryzae…”
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Investigating the Human Host-ssRNA Virus Interaction Landscape Using the SMEAGOL Toolbox
Published in Viruses (29-06-2022)“…Viruses have evolved numerous mechanisms to exploit the molecular machinery of their host cells, including the broad spectrum of host RNA-binding proteins…”
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Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice
Published in Viruses (21-07-2020)“…Insertions of endogenous retroviruses cause a significant fraction of mutations in inbred mice but not all strains are equally susceptible. Notably, most new…”
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Trypanosoma cruzi XRNA granules colocalise with distinct mRNP granules at the nuclear periphery
Published in Memórias do Instituto Oswaldo Cruz (2018)“…BACKGROUND Eukaryotic ribonucleoprotein (RNP) granules are important for the regulation of RNA fate. RNP granules exist in trypanosomatids; however, their…”
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MOOMIN – Mathematical explOration of ’Omics data on a MetabolIc Network
Published in Bioinformatics (15-01-2020)“…Abstract Motivation Analysis of differential expression of genes is often performed to understand how the metabolic activity of an organism is impacted by a…”
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Phenotypic and Transcriptomic Responses to Stress Differ According to Population Geography in an Invasive Species
Published in Genome biology and evolution (01-09-2021)“…Abstract Adaptation to rapid environmental changes must occur within a short-time scale. In this context, studies of invasive species may provide insights into…”
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Modulation of IKlebsiella pneumoniae/I Outer Membrane Vesicle Protein Cargo under Antibiotic Treatment
Published in Biomedicines (01-05-2023)“…Klebsiella pneumoniae is a nosocomial pathogen and an important propagator of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. Like…”
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20
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
Published in Nature cell biology (01-07-2021)“…Haematopoietic stem cells (HSCs) are normally quiescent, but have evolved mechanisms to respond to stress. Here, we evaluate haematopoietic regeneration…”
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