Search Results - "Gally, Fabienne"

Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter by Rao, Deviyani, Perraud, Anne-Laure, Schmitz, Carsten, Gally, Fabienne

“…Cigarette smoking is the primary cause of chronic obstructive pulmonary disease (COPD) with repeated and sustained infections linked to disease pathogenesis…”
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Cigarette smoke decreases airway epithelial FABP5 expression and promotes Pseudomonas aeruginosa infection by Gally, Fabienne, Chu, Hong Wei, Bowler, Russell P

“…Cigarette smoking is the primary cause of Chronic Obstructive Pulmonary Disease (COPD), which is characterized by chronic inflammation of the airways and…”
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FABP5 deficiency enhances susceptibility to H1N1 influenza A virus-induced lung inflammation by Gally, Fabienne, Kosmider, Beata, Weaver, Michael R, Pate, Kathryn M, Hartshorn, Kevan L, Oberley-Deegan, Rebecca E

“…The early inflammatory response to influenza A virus infection contributes to severe lung disease and continues to pose a serious threat to human health. The…”
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Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury by Ni, Kevin, Gill, Amar, Tseng, Victor, Mikosz, Andrew M, Koike, Kengo, Beatman, Erica L, Xu, Cassie Y, Cao, Danting, Gally, Fabienne, Mould, Kara J, Serban, Karina A, Schweitzer, Kelly S, March, Keith L, Janssen, William J, Nozik-Grayck, Eva, Garantziotis, Stavros, Petrache, Irina

“…Several inflammatory lung diseases display abundant presence of hyaluronic acid (HA) bound to heavy chains (HC) of serum protein inter-alpha-inhibitor (IαI) in…”
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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling by Gally, Fabienne, Sasse, Sarah K, Kurche, Jonathan S, Gruca, Margaret A, Cardwell, Jonathan H, Okamoto, Tsukasa, Chu, Hong W, Hou, Xiaomeng, Poirion, Olivier B, Buchanan, Justin, Preissl, Sebastian, Ren, Bing, Colgan, Sean P, Dowell, Robin D, Yang, Ivana V, Schwartz, David A, Gerber, Anthony N

“…The G/T transversion rs35705950, located approximately 3 kb upstream of the MUC5B start site, is the cardinal risk factor for idiopathic pulmonary fibrosis…”
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Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection by Rao, Deviyani M., Phan, Della T., Choo, Michelle J., Weaver, Michael R., Oberley-Deegan, Rebecca E., Bowler, Russell P., Gally, Fabienne

“…Background Although cigarette smoking (CS) is by far the most important risk factor of chronic obstructive pulmonary disease (COPD), repeated and sustained…”
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Airway epithelial NF-κB activation promotes Mycoplasma pneumoniae clearance in mice by Jiang, Di, Nelson, Mark L, Gally, Fabienne, Smith, Sean, Wu, Qun, Minor, Maisha, Case, Stephanie, Thaikoottathil, Jyoti, Chu, Hong Wei

“…Respiratory infections including atypical bacteria Mycoplasma pneumoniae (Mp) contribute to the pathobiology of asthma and chronic obstructive pulmonary…”
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Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model by Green, Rebecca M, Gally, Fabienne, Keeney, Jonathon G, Alper, Scott, Gao, Bifeng, Han, Min, Martin, Richard J, Weinberger, Andrew R, Case, Stephanie R, Minor, Maisha N, Chu, Hong Wei

“…Cigarette smoking is the major cause of chronic obstructive pulmonary disease (COPD) and lung cancer. Respiratory bacterial infections have been shown to be…”
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The metalloporphyrin antioxidant, MnTE-2-PyP, inhibits Th2 cell immune responses in an asthma model by Jungsuwadee, Paiboon, Weaver, Michael R, Gally, Fabienne, Oberley-Deegan, Rebecca E

“…MnTE-2-PyP, a superoxide dismutase mimetic, inhibited OVA-induced airway inflammation in mice suggesting an effect on Th2 responsiveness. Thus, we hypothesized…”
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SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signaling by Chu, Hong Wei, Gally, Fabienne, Thaikoottathil, Jyoti, Janssen-Heininger, Yvonne M, Wu, Qun, Zhang, Gongyi, Reisdorph, Nichole, Case, Stephanie, Minor, Maisha, Smith, Sean, Jiang, Di, Michels, Nicole, Simon, Glenn, Martin, Richard J

“…Respiratory infections including Mycoplasma pneumoniae (Mp) contribute to various chronic lung diseases. We have shown that mouse short palate, lung, and nasal…”
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Absence of the fatty acid binding protein5 (FABP5) inhibits the establishment of resident memory T cells after a secondary Listeria monocytogenes infection by Aviszus, Katja, Giron, Aaron, El Kharbili DiLisio, Manale, Zhao, Xiaoyun, Gally, Fabienne

“…Abstract Fatty acid binding protein 5 (FABP5) is a member of the family of fatty acid binding proteins involved in fatty acid uptake, transport, and…”
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Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression by Sasse, Sarah K, Gruca, Margaret, Allen, Mary A, Kadiyala, Vineela, Song, Tengyao, Gally, Fabienne, Gupta, Arnav, Pufall, Miles A, Dowell, Robin D, Gerber, Anthony N

“…The glucocorticoid receptor (NR3C1, also known as GR) binds to specific DNA sequences and directly induces transcription of anti-inflammatory genes that…”
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Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator‐activated receptor γ by El Kharbili, Manale, Aviszus, Katja, Sasse, Sarah K., Zhao, Xiaoyun, Serban, Karina A., Majka, Susan M., Gerber, Anthony N., Gally, Fabienne

“…Resolution of inflammation is an active process that is tightly regulated to achieve repair and tissue homeostasis. In the absence of resolution, persistent…”
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Noncoding SNPs decrease expression of FABP5 during COPD exacerbations by El Kharbili, Manale, Sasse, Sarah K, Sanford, Lynn, Jacobson, Sean, Aviszus, Katja, Gupta, Arnav, Guo, Claire, Majka, Susan M, Dowell, Robin D, Gerber, Anthony N, Bowler, Russell P, Gally, Fabienne

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Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions by Mikosz, Andrew, Ni, Kevin, Gally, Fabienne, Pratte, Katherine A, Winfree, Seth, Lin, Qiong, Echelman, Isabelle, Wetmore, Brianna, Cao, Danting, Justice, Matthew J, Sandhaus, Robert A, Maier, Lisa, Strange, Charlie, Bowler, Russell P, Petrache, Irina, Serban, Karina A

“…Chronic obstructive pulmonary disease (COPD) is characterized by nonresolving inflammation fueled by breach in the endothelial barrier and leukocyte…”
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Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis by Borie, Raphael, Cardwell, Jonathan, Konigsberg, Iain R, Moore, Camille M, Zhang, Weiming, Sasse, Sarah K, Gally, Fabienne, Dobrinskikh, Evgenia, Walts, Avram, Powers, Julie, Brancato, Janna, Rojas, Mauricio, Wolters, Paul J, Brown, Kevin K, Blackwell, Timothy S, Nakanishi, Tomoko, Richards, J Brent, Gerber, Anthony N, Fingerlin, Tasha E, Sachs, Norman, Pulit, Sara L, Zappala, Zachary, Schwartz, David A, Yang, Ivana V

“…Common genetic variants have been associated with idiopathic pulmonary fibrosis (IPF). To determine functional relevance of the 10 IPF-associated common…”
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Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging by Mason, Emma C, Menon, Swapna, Schneider, Benjamin R, Gaskill, Christa F, Dawson, Maggie M, Moore, Camille M, Armstrong, Laura Craig, Cho, Okyong, Richmond, Bradley W, Kropski, Jonathan A, West, James D, Geraghty, Patrick, Gomperts, Brigitte N, Ess, Kevin C, Gally, Fabienne, Majka, Susan M

“…Reactivation and dysregulation of the mTOR signaling pathway are a hallmark of aging and chronic lung disease; however, the impact on microvascular progenitor…”
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Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency by Poczobutt, Joanna M, Mikosz, Andrew M, Poirier, Christophe, Beatman, Erica L, Serban, Karina A, Gally, Fabienne, Cao, Danting, McCubbrey, Alexandra L, Cornell, Christina F, Schweitzer, Kelly S, Berdyshev, Evgeny V, Bronova, Irina A, Paris, François, Petrache, Irina

“…Deficiency of ASM (acid sphingomyelinase) causes the lysosomal storage Niemann-Pick disease (NPD). Patients with NPD type B may develop progressive…”
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FABP5 Deficiency Enhances Susceptibility to H1N1 Influenza a Virus-Induced Lung Inflammation by Gally, Fabienne, Pate, Kathryn, Weaver, Michael, Oberley-Deegan, Rebecca

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The TRPM2 ion channel contributes to cytokine hyperproduction in a mouse model of Down Syndrome by Gally, Fabienne, Rao, Deviyani M., Schmitz, Carsten, Colvin, Kelley L., Yeager, Michael E., Perraud, Anne-Laure

“…Trisomy 21 (Down Syndrome, DS) is the most common chromosomal anomaly. Although DS is mostly perceived as affecting cognitive abilities and cardiac health,…”
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