Search Results - "Galluccio, N"
-
1
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
Published in British journal of cancer (18-08-2009)“…Background: KRAS codons 12 and 13 mutations predict resistance to anti-EGFR monoclonal antibodies (moAbs) in metastatic colorectal cancer. Also, BRAF V600E…”
Get full text
Journal Article -
2
Genetic modulation of the Let-7 microRNA binding to KRAS 3′-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab–irinotecan
Published in The pharmacogenomics journal (01-10-2010)“…There is increasing evidence that the Let-7 microRNA (miRNA) exerts an effect as a tumor suppressor by targeting the KRAS mRNA. The Let-7 complementary site…”
Get full text
Journal Article -
3
High concordance of BRAF status between primary colorectal tumours and related metastatic sites: implications for clinical practice
Published in Annals of oncology (01-07-2010)Get full text
Journal Article -
4
Role of KRAS let-7 LCS6 SNP in metastatic colorectal cancer patients
Published in Annals of oncology (01-01-2011)Get full text
Journal Article -
5
Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer
Published in The pharmacogenomics journal (01-02-2009)“…The interleukin-1 receptor antagonist (IL-1RA) cytokine is thought to counteract tumor angiogenesis/metastasis. Two single nucleotide polymorphisms in the…”
Get full text
Journal Article -
6
Retrospective exploratory analysis of VEGF polymorphisms in the prediction of benefit from first-line FOLFIRI plus bevacizumab in metastatic colorectal cancer
Published in BMC cancer (14-06-2011)“…Molecular predictors of bevacizumab efficacy in colorectal cancer have not been identified yet. Specific VEGF polymorphisms may affect gene transcription and…”
Get full text
Journal Article -
7
Let-7a microRNA levels in KRAS -mutated colorectal carcinomas determine survival differences in patients treated with anti-EGFR
Published in Journal of clinical oncology (20-05-2011)“…Abstract only…”
Get full text
Journal Article -
8
C-MET gene copy number variation (CNV) analysis by quantitative PCR (qPCR) assay in Caucasian patients with gastric cancer (GC)
Published in Journal of clinical oncology (20-05-2011)“…Abstract only…”
Get full text
Journal Article