Search Results - "Galloway, S.M."

Investigation of the Booroola ( FecB) and Inverdale ( FecX I ) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries by Davis, G.H., Balakrishnan, L., Ross, I.K., Wilson, T., Galloway, S.M., Lumsden, B.M., Hanrahan, J.P., Mullen, M., Mao, X.Z., Wang, G.L., Zhao, Z.S., Zeng, Y.Q., Robinson, J.J., Mavrogenis, A.P., Papachristoforou, C., Peter, C., Baumung, R., Cardyn, P., Boujenane, I., Cockett, N.E., Eythorsdottir, E., Arranz, J.J., Notter, D.R.

“…Twenty-one of the world's prolific sheep breeds and strains were tested for the presence of the FecB mutation of BMPR1B and the FecX I mutation of BMP15. The…”
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Regulatory aspects of genotoxicity testing: from hazard identification to risk assessment by Blakey, D, Galloway, S M, Kirkland, D J, MacGregor, J T

“…This symposium focused on the use of tests for chromosomal damage, and other genotoxicity measures, for detection of potentially harmful chemicals. The…”
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A putative autosomal gene increasing ovulation rate in Romney sheep by Davis, G.H., Farquhar, P.A., O’Connell, A.R., Everett-Hincks, J.M., Wishart, P.J., Galloway, S.M., Dodds, K.G.

“…Ovulation rates were measured in 547 progeny of 24 rams in a Romney flock with a long history of high prolificacy. These sheep were from the same family line…”
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UDP-N-acetylglucosamine acyltransferase of Escherichia coli. The first step of endotoxin biosynthesis is thermodynamically unfavorable by ANDERSON, M. S, BULL, H. G, GALLOWAY, S. M, KELLY, T. M, SANDHYA MOHAN, RADIKA, K, RAETZ, C. R. H

“…UDP-N-acetylglucosamine acyltransferase of Escherichia coli catalyzes the reaction, UDP-GlcNAc + R-3-hydroxymyristoyl-ACP-->…”
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Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries) by HANRAHAN, James P, GREGAN, Scott M, MULSANT, Philippe, MULLEN, Michael, DAVIS, George H, POWELL, Richard, GALLOWAY, Susan M

“…Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting ewes with exceptionally high litter size records from commercial…”
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Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides by Bercu, J.P., Galloway, S.M., Parris, P., Teasdale, A., Masuda-Herrera, M., Dobo, K., Heard, P., Kenyon, M., Nicolette, J., Vock, E., Ku, W., Harvey, J., White, A., Glowienke, S., Martin, E.A., Custer, L., Jolly, R.A., Thybaud, V.

“…This paper provides compound-specific toxicology limits for 20 widely used synthetic reagents and common by-products that are potential impurities in drug…”
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Bacterial mutagenicity screening in the pharmaceutical industry by Escobar, P.A., Kemper, R.A., Tarca, J., Nicolette, J., Kenyon, M., Glowienke, S., Sawant, S.G., Christensen, J., Johnson, T.E., McKnight, C., Ward, G., Galloway, S.M., Custer, L., Gocke, E., O’Donovan, M.R., Braun, K., Snyder, R.D., Mahadevan, B.

“…Genetic toxicity testing is used as an early surrogate for carcinogenicity testing. Genetic toxicity testing is also required by regulatory agencies to be…”
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Alkaline comet assay in liver and stomach, and micronucleus assay in bone marrow, from rats treated with 2-acetylaminofluorene, azidothymidine, cisplatin, or isobutyraldehyde by Kraynak, A.R., Barnum, J.E., Cunningham, C.L., Ng, A., Ykoruk, B.A., Bennet, B., Stoffregen, D., Merschman, M., Freeland, E., Galloway, S.M.

“…•Validation studies of the in vivo rat alkaline comet assay in liver and stomach.•Studies coordinated by Japanese Center for the Validation of Alternative…”
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Investigations into the GDF8 g+6723G-A polymorphism in New Zealand Texel sheep by Johnson, P.L, Dodds, K.G, Bain, W.E, Greer, G.J, McLean, N.J, McLaren, R.J, Galloway, S.M, van Stijn, T.C, McEwan, J.C

“…This work investigated effects of carrying 0, 1, or 2 copies of the A allele resulting from the g+6723G-A transition in growth differentiation factor gene…”
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Physiology of GDF9 and BMP15 signalling molecules by Juengel, J.L, Bodensteiner, K.J, Heath, D.A, Hudson, N.L, Moeller, C.L, Smith, P, Galloway, S.M, Davis, G.H, Sawyer, H.R, McNatty, K.P

“…Two related oocyte-derived members of the transforming growth factor-β (TGF-β) superfamily, namely growth differentiation factor 9 (GDF9) and bone…”
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Corrigendum to “Bacterial mutagenicity screening in the pharmaceutical industry” [Mutat. Res. 752(2) (2013) 99-118] by Escobar, P.A., Kemper, R.A., Tarca, J., Nicolette, J., Kenyon, M., Glowienke, S., Sawant, S.G., Christensen, J., Johnson, T.E., McKnight, C., Ward, G., Galloway, S.M., Custer, L., Gocke, E., O’Donovan, M.R., Braun, K., Snyder, R.D., Mahadevan, B.

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linkage map of Sheep Chromosome X (OARX) aligned to Human Chromosome X (HSAX) by French, M.C, Dodds, K.G, Davis, G.H, Galloway, S.M, Edwards, S.J

“…We have constructed a genetic linkage map of the sheep X chromosome (OARX) containing 22 new gene loci from across the human X chromosome (HSAX). The female…”
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Bmp15 mutations and ovarian function by Galloway, S.M., Gregan, S.M., Wilson, T., McNatty, K.P., Juengel, J.L., Ritvos, O., Davis, G.H.

“…BMP15, also known as growth and differentiation factor 9B (GDF9B), is a member of the transforming growth factor beta superfamily (TGFβ) which in humans,…”
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Thalidomide: lack of mutagenic activity across phyla and genetic endpoints by Ashby, J, Tinwell, H, Callander, R D, Kimber, I, Clay, P, Galloway, S M, Hill, R B, Greenwood, S K, Gaulden, M E, Ferguson, M J, Vogel, E, Nivard, M, Parry, J M, Williamson, J

“…The human and rabbit teratogen thalidomide has been tested for mutagenicity in a wide range of assays, ranging from bacterial gene mutation assays conducted in…”
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Vitamin C is positive in the DNA synthesis inhibition and sister-chromatid exchange tests by Galloway, S M, Painter, R B

“…Ascorbate caused a dose-dependent increase in sister-chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells and in human lymphocytes. Moreover, in the…”
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The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4q by Montgomery, G.W, Crawford, A.M, Penty, J.M, Doods, K.G, Ede, A.J, Henry, H.M, Pierson, C.A, Lord, E.A, Galloway, S.M, Schmack, A.E

“…The autosomal Booroola fecundity gene (FecB) mutation in sheep increases ovulation rate and litter size, with associated effects on ovarian physiology and…”
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Comparative mapping of sheep chromosome 2q by van Stijn, T C, French, M C, Dodds, K G, McEwan, J C, Broad, T E, Womack, J E, Tisdall, D J, Galloway, S M

“…Sheep chromosome 2q (OAR2q), which is homologous with human chromosome 2q (HSA2q), and cattle chromosome 2 (BTA2), is known to contain several loci…”
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An enhanced linkage map of the sheep genome comprising more than 1000 loci by Maddox, J F, Davies, K P, Crawford, A M, Hulme, D J, Vaiman, D, Cribiu, E P, Freking, B A, Beh, K J, Cockett, N E, Kang, N, Riffkin, C D, Drinkwater, R, Moore, S S, Dodds, K G, Lumsden, J M, van Stijn, T C, Phua, S H, Adelson, D L, Burkin, H R, Broom, J E, Buitkamp, J, Cambridge, L, Cushwa, W T, Gerard, E, Galloway, S M, Harrison, B, Hawken, R J, Hiendleder, S, Henry, H M, Medrano, J F, Paterson, K A, Schibler, L, Stone, R T, van Hest, B

“…A medium-density linkage map of the ovine genome has been developed. Marker data for 550 new loci were generated and merged with the previous sheep linkage…”
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Characterisation and mapping of the Booroola ( FecB ) gene using regression analysis in sheep by Walling, G.A., Dodds, K.G., Galloway, S.M., Beattie, A.E., Lord, E.A., Lumsden, J.M., Montgomery, G.W., McEwan, J.C.

“…The Booroola Merino strain of sheep carries a major autosomal mutation ( FecB ) which increases ovulation rate (Davis et al. , 1982). To map the gene,…”
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The consequences of carrying the Booroola fecundity ( FecB ) gene on sheep liveweight by Walling, G.A., Dodds, K.G., Galloway, S.M., Beattie, A.E., Lord, E.A., Lumsden, J.M., Montgomery, G.W., McEwan, J.C.

“…The increase in ovulation rate caused by the Booroola gene was first observed in the Booroola Merino strain of sheep (Davis et al. , 1982) and the gene was…”
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