Search Results - "Galligan, A."

The imaging of immunotherapy-related hypophysitis and other pituitary lesions in oncology patients by Lasocki, A., Iravani, A., Galligan, A.

“…Immunotherapy has revolutionised the treatment of metastatic disease from a variety of different primaries, but is frequently associated with immune-related…”
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CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells by JACOBS, Elizabeth T, VAN PELT, Chad, FORSTER, Ryan E, ZAIDI, Wasiq, HIBLER, Elizabeth A, GALLIGAN, Michael A, HAUSSLER, Mark R, JURUTKA, Peter W

“…Vitamin D is a well-studied agent for cancer chemoprevention and treatment. Its chief circulating metabolite, 25-hydroxyvitamin D, is converted into the active…”
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Diabetes associated with immune checkpoint inhibition: presentation and management challenges by Galligan, A., Xu, W., Fourlanos, S., Nankervis, A., Chiang, C., Mant, A. M., Parente, P., Rischin, D., Krishnamurthy, B., Sandhu, S., Colman, P. G.

“…Background In recent years, immune checkpoint blockade has become a standard therapy for a wide range of cancers. Adverse events, including endocrinopathies,…”
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Novel approaches to the treatment of hyperglycaemia in type 2 diabetes mellitus by Galligan, A., Greenaway, T. M.

“…Control of hyperglycaemia is a fundamental therapeutic goal in patients with type 2 diabetes. The progressive nature of β‐cell dysfunction in type 2 diabetes…”
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Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene by Kerr Whitfield, G, Remus, Lenore S, Jurutka, Peter W, Zitzer, Heike, Oza, Anish K, Dang, Hope T.L, Haussler, Carol A, Galligan, Michael A, Thatcher, Michelle L, Dominguez, Carlos Encinas, Haussler, Mark R

“…The functional significance of two unlinked human vitamin D receptor (hVDR) gene polymorphisms was evaluated in twenty human fibroblast cell lines. Genotypes…”
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Effect of leukoreduction on transfusion-induced inflammation in dogs by McMichael, M.A, Smith, S.A, Galligan, A, Swanson, K.S, Fan, T.M

“…Background: Removal of leukocytes (LR) has been shown to eliminate or attenuate many of the adverse effects of transfusion in experimental animals and humans…”
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Associations between vitamin D-binding protein isotypes, circulating 25(OH)D levels, and vitamin D metabolite uptake in colon cancer cells by Hibler, Elizabeth A, Jacobs, Elizabeth T, Stone, Angelika Dampf, Sardo, Christine L, Galligan, Michael A, Jurutka, Peter W

“…Vitamin D metabolites have been extensively studied as cancer chemopreventive agents. Gc-globulin (GC) isotypes, based on rs7041 and rs4588 diplotypes, have…”
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The Polymorphic N Terminus in Human Vitamin D Receptor Isoforms Influences Transcriptional Activity by Modulating Interaction with Transcription Factor IIB by Jurutka, Peter W, Remus, Lenore S, Whitfield, G. Kerr, Thompson, Paul D, Hsieh, J.-C, Zitzer, Heike, Tavakkoli, Poupak, Galligan, Michael A, Dang, Hope T. L, Haussler, Carol A, Haussler, Mark R

“…The human vitamin D receptor (hVDR) is a ligand-regulated transcription factor that mediates the actions of the 1,25-dihydroxyvitamin D3 hormone to effect bone…”
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Gunshot Wound Trajectory Analysis Using Forensic Animation to Establish Relative Positions of Shooter and Victim by Galligan, Aisling A, Fries, Craig, Melinek, Judy

“…Highlights • Forensic pathologists are often asked to analyze bullet trajectory in order to determine the relative position of the shooter and victim. •…”
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Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene by MACDONALD, P. N, DOWD, D. R, NAKAJIMA, S, GALLIGAN, M. A, REEDER, M. C, HAUSSLER, C. A, OZATO, K, HAUSSLER, M. R

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via vitamin D receptor deacetylation by Sabir, Marya S., Khan, Zainab, Hu, Chengcheng, Galligan, Michael A., Dussik, Christopher M., Mallick, Sanchita, Stone, Angelika Dampf, Batie, Shane F., Jacobs, Elizabeth T., Whitfield, G. Kerr, Haussler, Mark R., Heck, Michael C., Jurutka, Peter W.

“…•Human VDR is post-translationally modified via acetylation, in part at lysine-413.•VDR deacetylation is mediated by SIRT1, and is enhanced by resveratrol, a…”
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Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts by Thompson, PD, Remus, LS, Hsieh, JC, Jurutka, PW, Whitfield, GK, Galligan, MA, Encinas Dominguez, C, Haussler, CA, Haussler, MR

“…The vitamin D receptor (VDR) stimulates transcription as a 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3))-activated heterodimer with retinoid X receptor (RXR)…”
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SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D 3 signaling via vitamin D receptor deacetylation by Sabir, Marya S, Khan, Zainab, Hu, Chengcheng, Galligan, Michael A, Dussik, Christopher M, Mallick, Sanchita, Stone, Angelika Dampf, Batie, Shane F, Jacobs, Elizabeth T, Whitfield, G Kerr, Haussler, Mark R, Heck, Michael C, Jurutka, Peter W

“…The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a…”
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Human Vitamin D Receptor is Selectively Phosphorylated by Protein Kinase C on Serine 51, a Residue Crucial to Its Trans-Activation Function by Hsieh, Jui-Cheng, Jurutka, Peter W., Galligan, Michael A., Terpening, Christopher M., Haussler, Carol A., Samuels, D. Scott, Shimizu, Yohiko, Shimizu, Nobuyoshi, Haussler, Mark R.

“…The vitamin D receptor (VDR) is known to be a phosphoprotein and inspection of the deduced amino acid sequence of human VDR (hVDR) reveals the conservation of…”
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Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site by JUI-CHENG HSIEH, JURUTKA, P. W, NAKAJIMA, S, GALLIGAN, M. A, HAUSSLER, C. A, SHIMIZU, Y, SHIMIZU, N, WHITFIELD, G. K, HAUSSLER, M. R

“…We have reported previously that the human vitamin D receptor (hVDR) is selectively phosphorylated by protein kinase C-beta (PKC-beta), in vitro, on a serine…”
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Characterization of Unique DNA-Binding and Transcriptional-Activation Functions in the Carboxyl-Terminal Extension of the Zinc Finger Region in the Human Vitamin D Receptor by Hsieh, Jui-Cheng, Whitfield, G. Kerr, Oza, Anish K, Dang, Hope T. L, Price, Jack N, Galligan, Michael A, Jurutka, Peter W, Thompson, Paul D, Haussler, Carol A, Haussler, Mark R

“…The vitamin D receptor (VDR) binds 1,25-dihydroxyvitamin D3 and mediates its actions on gene transcription by heterodimerizing with retinoid X receptors (RXRs)…”
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Ion beam alignment for liquid crystal display fabrication by Doyle, J.P., Chaudhari, P., Lacey, J.L., Galligan, E.A., Lien, S.C., Callegari, A.C., Lang, N.D., Lu, M., Nakagawa, Y., Nakano, H., Okazaki, N., Odahara, S., Katoh, Y., Saitoh, Y., Sakai, K., Satoh, H., Shiota, Y.

“…The ability to align liquid crystals to a substrate is a critical step in the liquid crystal display (LCD) manufacturing process with the industry standard…”
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The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element by Nakajima, S, Hsieh, J C, MacDonald, P N, Galligan, M A, Haussler, C A, Whitfield, G K, Haussler, M R

“…The human vitamin D receptor (hVDR) requires another nuclear protein(s), designated receptor auxiliary factor (RAF), for optimal binding to the vitamin…”
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Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor by MacDonald, P N, Haussler, C A, Terpening, C M, Galligan, M A, Reeder, M C, Whitfield, G K, Haussler, M R

“…A baculovirus expression vector system (BEVS) was used to overproduce the full-length human vitamin D receptor (hVDR) in Spodoptera frugiperda ovarian cells…”
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Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor by Jurutka, Peter W., MacDonald, Paul N., Nakajima, Shigeo, Hsieh, Jui-Cheng, Thompson, Paul D, Whitfield, G. Kerr, Galligan, Michael A., Haussler, Carol A., Haussler, Mark R.

“…Two controversial aspects in the mechanism of human vitamin D receptor (hVDR) action are the possible significance of VDR homodimers and the functional role of…”
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