Search Results - "Galli, SJ"

Mast cells to the defense by Galli, Stephen J, Nakae, Susumu

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Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent : partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha by WERSHIL, B. K, ZHEN-SHENG WANG, GORDON, J. R, GALLI, S. J

“…Much of the clinically important pathology associated with IgE-dependent disorders is thought to reflect the actions of the blood-borne leukocytes recruited…”
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Mast cells in the development of adaptive immune responses by Galli, Stephen J, Nakae, Susumu, Tsai, Mindy

“…Mast cells are so widely recognized as critical effector cells in allergic disorders and other immunoglobulin E-associated acquired immune responses that it…”
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Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future by Valent, Peter, Akin, Cem, Hartmann, Karin, Nilsson, Gunnar, Reiter, Andreas, Hermine, Olivier, Sotlar, Karl, Sperr, Wolfgang R, Escribano, Luis, George, Tracy I, Kluin-Nelemans, Hanneke C, Ustun, Celalettin, Triggiani, Massimo, Brockow, Knut, Gotlib, Jason, Orfao, Alberto, Schwartz, Lawrence B, Broesby-Olsen, Sigurd, Bindslev-Jensen, Carsten, Kovanen, Petri T, Galli, Stephen J, Austen, K Frank, Arber, Daniel A, Horny, Hans-Peter, Arock, Michel, Metcalfe, Dean D

“…Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the expansion and accumulation of clonal (neoplastic) tissue mast cells in…”
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Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts by Valent, Peter, Akin, Cem, Hartmann, Karin, Nilsson, Gunnar, Reiter, Andreas, Hermine, Olivier, Sotlar, Karl, Sperr, Wolfgang R, Escribano, Luis, George, Tracy I, Kluin-Nelemans, Hanneke C, Ustun, Celalettin, Triggiani, Massimo, Brockow, Knut, Gotlib, Jason, Orfao, Alberto, Kovanen, Petri T, Hadzijusufovic, Emir, Sadovnik, Irina, Horny, Hans-Peter, Arock, Michel, Schwartz, Lawrence B, Austen, K Frank, Metcalfe, Dean D, Galli, Stephen J

“…The origin and functions of mast cells (MCs) have been debated since their description by Paul Ehrlich in 1879. MCs have long been considered 'reactive…”
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Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal by Valent, Peter, Akin, Cem, Hartmann, Karin, Alvarez‐Twose, Ivan, Brockow, Knut, Hermine, Olivier, Niedoszytko, Marek, Schwaab, Juliana, Lyons, Jonathan J., Carter, Melody C., Elberink, Hanneke Oude, Butterfield, Joseph H., George, Tracy I., Greiner, Georg, Ustun, Celalettin, Bonadonna, Patrizia, Sotlar, Karl, Nilsson, Gunnar, Jawhar, Mohamad, Siebenhaar, Frank, Broesby‐Olsen, Sigurd, Yavuz, Selim, Zanotti, Roberta, Lange, Magdalena, Nedoszytko, Boguslaw, Hoermann, Gregor, Castells, Mariana, Radia, Deepti H., Muñoz‐Gonzalez, Javier I., Sperr, Wolfgang R., Triggiani, Massimo, Kluin‐Nelemans, Hanneke C., Galli, Stephen J., Schwartz, Lawrence B., Reiter, Andreas, Orfao, Alberto, Gotlib, Jason, Arock, Michel, Horny, Hans‐Peter, Metcalfe, Dean D.

“…Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin,…”
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Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF by Nakae, Susumu, Suto, Hajime, Iikura, Motoyasu, Kakurai, Maki, Sedgwick, Jonathon D, Tsai, Mindy, Galli, Stephen J

“…We recently reported that mast cells stimulated via FcepsilonRI aggregation can enhance T cell activation by a TNF-dependent mechanism. However, the molecular…”
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Mast cells as "tunable" effector and immunoregulatory cells: recent advances by Galli, Stephen J, Kalesnikoff, Janet, Grimbaldeston, Michele A, Piliponsky, Adrian M, Williams, Cara M M, Tsai, Mindy

“…This review focuses on recent progress in our understanding of how mast cells can contribute to the initiation, development, expression, and regulation of…”
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Regulation of mast-cell and basophil function and survival by IgE by Galli, Stephen J, Kawakami, Toshiaki

“…Mast cells and basophils are important effector cells in T helper 2 (T(H)2)-cell-dependent, immunoglobulin-E-associated allergic disorders and immune responses…”
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Identification of Mast Cell Progenitors in Adult Mice by Chen, Ching-Cheng, Grimbaldeston, Michele A., Tsai, Mindy, Weissman, Irving L., Galli, Stephen J.

“…It is well known that mast cells are derived from hematopoietic stem cells. However, in adult hematopoiesis, a committed mast cell progenitor has not yet been…”
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Second Symposium on the Definition and Management of Anaphylaxis: Summary Report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium by Sampson, Hugh A., Muñoz-Furlong, Anne, Campbell, Ronna L., Adkinson, N. Franklin, Allan Bock, S., Branum, Amy, Brown, Simon G.A., Camargo, Carlos A., Cydulka, Rita, Galli, Stephen J., Gidudu, Jane, Gruchalla, Rebecca S., Harlor, Allen D., Hepner, David L., Lewis, Lawrence M., Lieberman, Phillip L., Metcalfe, Dean D., O’Connor, Robert, Muraro, Antonella, Rudman, Amanda, Schmitt, Cara, Scherrer, Debra, Simons, F. Estelle, Thomas, Stephen, Wood, Joseph P., Decker, Wyatt W.

“…There is no universal agreement on the definition of anaphylaxis or the criteria for diagnosis. In July 2005, the National Institute of Allergy and Infectious…”
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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis by Heller, Renu, Steinman, Lawrence, Lock, Christopher, Hermans, Guy, Pedotti, Rosetta, Brendolan, Andrea, Schadt, Eric, Garren, Hideki, Langer-Gould, Annette, Strober, Samuel, Cannella, Barbara, Allard, John, Klonowski, Paul, Austin, Angela, Lad, Nagin, Kaminski, Naftali, Galli, Stephen J, Oksenberg, Jorge R, Raine, Cedric S

“…Microarray analysis of multiple sclerosis (MS) lesions obtained at autopsy revealed increased transcripts of genes encoding inflammatory cytokines,…”
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Mast cells promote homeostasis by limiting endothelin-1-induced toxicity by Galli, Stephen J, Maurer, Marcus, Wedemeyer, Jochen, Metz, Martin, Piliponsky, Adrian M, Weller, Karsten, Chatterjea, Devavani, Clouthier, David E, Yanagisawa, Masashi M, Tsai, Mindy

“…Endothelin-1 (ET-1) is a 21-amino-acid peptide, derived from vascular endothelial cells, with potent vasoconstrictor activity. ET-1 has been implicated in…”
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The Normal Range of Baseline Tryptase Should Be 1 to 15 ng/mL and Covers Healthy Individuals With HαT by Valent, Peter, Hoermann, Gregor, Bonadonna, Patrizia, Hartmann, Karin, Sperr, Wolfgang R., Broesby-Olsen, Sigurd, Brockow, Knut, Niedoszytko, Marek, Hermine, Olivier, Chantran, Yannick, Butterfield, Joseph H., Greiner, Georg, Carter, Melody C., Sabato, Vito, Radia, Deepti H., Siebenhaar, Frank, Triggiani, Massimo, Gülen, Theo, Alvarez-Twose, Ivan, Staudinger, Thomas, Traby, Ludwig, Sotlar, Karl, Reiter, Andreas, Horny, Hans-Peter, Orfao, Alberto, Galli, Stephen J., Schwartz, Lawrence B., Lyons, Jonathan J., Gotlib, Jason, Metcalfe, Dean D., Arock, Michel, Akin, Cem

“…Physiological levels of basal serum tryptase vary among healthy individuals, depending on the numbers of mast cells, basal secretion rate, copy numbers of the…”
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Mast Cells Enhance T Cell Activation: Importance of Mast Cell-Derived TNF by Nakae, Susumu, Suto, Hajime, Kakurai, Maki, Sedgwick, Jonathon D., Tsai, Mindy, Galli, Stephen J., McDevitt, Hugh O.

“…Mast cells are not only important effector cells in immediate hypersensitivity reactions and immune responses to pathogens but also can contribute to T…”
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Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice by Williams, C M, Galli, S J

“…The importance of mast cells in the development of the allergen-induced airway hyperreactivity and inflammation associated with asthma remains controversial…”
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Mast cells and basophils by Galli, Stephen J

“…Mast cells and basophils are effector cells in IgE-associated immune responses, such as those that contribute to asthma and other allergic diseases and to host…”
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Roles of mast cells and basophils in innate and acquired immunity by Wedemeyer, Jochen, Tsai, Mindy, Galli, Stephen J

“…There have been several recent advances in knowledge about mast cells and basophils in immune responses, of which some are particularly important: a role has…”
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Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation by Gotlib, Jason, Berubé, Caroline, Growney, Joseph D., Chen, Ching-Cheng, George, Tracy I., Williams, Christopher, Kajiguchi, Tomohiro, Ruan, Jia, Lilleberg, Stan L., Durocher, Jeffrey A., Lichy, Jack H., Wang, Yanfeng, Cohen, Pamela S., Arber, Daniel A., Heinrich, Michael C., Neckers, Len, Galli, Stephen J., Gilliland, D. Gary, Coutré, Steven E.

“…The majority of patients with systemic mast cell disease express the imatinib-resistant Asp816Val (D816V) mutation in the KIT receptor tyrosine kinase. Limited…”
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The diverse potential effector and immunoregulatory roles of mast cells in allergic disease by Williams, Cara M.M., Galli, Stephen J.

“…Mast cells are of hematopoietic origin but typically complete their maturation in peripheral connective tissues, especially those near epithelial surfaces…”
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