Search Results - "Galleway, Fiona"
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Imidazopyridines as VLA-4 integrin antagonists
Published in Bioorganic & medicinal chemistry (15-07-2008)“…The synthesis and SAR of a novel series of imidazopyridine VLA-4 antagonist is described. Compound 15c is a representative example of this series with a human…”
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2
Synthesis and structure–activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors
Published in Bioorganic & medicinal chemistry letters (23-04-2001)“…The synthesis of a novel series of guanine analogues is reported. The compounds have been assessed in vitro and some analogues have been found to be inhibitors…”
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3
7-Methoxyfuro[2,3- c]pyridine-4-carboxamides as PDE4 Inhibitors: A Potential Treatment for Asthma
Published in Bioorganic & medicinal chemistry letters (11-02-2002)“…The synthesis and pharmacological profile of a novel series of 7-methoxy-furo[2,3- c]pyridine-4-carboxamides is described. Some of these compounds were found…”
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4
PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
Published in Blood (18-03-2010)“…We have previously described critical and nonredundant roles for the phosphoinositide 3-kinase p110δ during the activation and differentiation of naive T…”
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5
8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma
Published in Bioorganic & medicinal chemistry letters (17-06-2002)“…A series of bicyclic heteroaryl ring systems was considered as a replacement for the 3-cyclopentyloxy-4-methoxyphenyl moiety in rolipram resulting in the…”
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6
Erratum to “Imidazopyridines as VLA-4 integrin antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 4146–4149]
Published in Bioorganic & medicinal chemistry letters (01-09-2008)Get full text
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7
PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
Published in Blood (18-03-2010)“…We have previously described critical and nonredundant roles for the phosphoinositide 3-kinase p110delta during the activation and differentiation of naive T…”
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Journal Article -
8
7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma
Published in Bioorganic & medicinal chemistry letters (18-09-2000)“…The synthesis and pharmacological profile of a novel series of 7-methoxybenzofuran-4-carboxamides is described. Some of these compounds were found to be potent…”
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