Search Results - "Galles, Grace D."

Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells by Galles, Grace D., Infield, Daniel T., Clark, Colin J., Hemshorn, Marcus L., Manikandan, Shivani, Fazan, Frederico, Rasouli, Ali, Tajkhorshid, Emad, Galpin, Jason D., Cooley, Richard B., Mehl, Ryan A., Ahern, Christopher A.

“…The aromatic side-chains of phenylalanine, tyrosine, and tryptophan interact with their environments via both hydrophobic and electrostatic interactions…”
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Cation-π Interactions and their Functional Roles in Membrane Proteins by Infield, Daniel T., Rasouli, Ali, Galles, Grace D., Chipot, Christophe, Tajkhorshid, Emad, Ahern, Christopher A.

“…[Display omitted] •Physicochemical characteristics are summarized.•Cation- π abundance is in membrane proteins assessed via automated structural…”
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Real-time observation of functional specialization among phosphorylation sites in CFTR by Infield, Daniel T, Schene, Miranda E, Fazan, Frederico S, Galles, Grace D, Galpin, Jason D, Ahern, Christopher A

“…Phosphoregulation is ubiquitous in biology. Defining the functional roles of individual phosphorylation sites within a multivalent system remains particularly…”
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Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte by Infield, Daniel T., Lueck, John D., Galpin, Jason D., Galles, Grace D., Ahern, Christopher A.

“…Chemical aminoacylation of orthogonal tRNA allows for the genetic encoding of a wide range of synthetic amino acids without the need to evolve specific…”
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Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape by Infield, Daniel T, Lee, Elizabeth E L, Galpin, Jason D, Galles, Grace D, Bezanilla, Francisco, Ahern, Christopher A

“…Voltage-dependent activation of voltage-gated cation channels results from the outward movement of arginine-bearing helices within proteinaceous voltage…”
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Site-Specific Encoding of Citrulline, a Neutral Analog of Arginine, to Study the Atomic Basis for Voltage-Dependent Gating In Ion Channels by Infield, Daniel T., Galpin, Jason D., Galles, Grace D., Ahern, Christopher A.

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Orthogonality of a Synthetic Pyrrolysine tRNA in the Xenopus Oocyte and its use to Encode Unnatural Amino Acids into Ion Channels by Infield, Daniel T., Lueck, John D., Galpin, Jason D., Galles, Grace D., Ahern, Christopher A.

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