Search Results - "Gallego, D."
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Phase separation directs ubiquitination of gene-body nucleosomes
Published in Nature (London) (01-03-2020)“…The conserved yeast E3 ubiquitin ligase Bre1 and its partner, the E2 ubiquitin-conjugating enzyme Rad6, monoubiquitinate histone H2B across gene bodies during…”
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Wars and kidney patients: a statement by the European Kidney Health Alliance related to the Russian-Ukrainian conflict
Published in Journal of nephrology (01-03-2022)Get full text
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Monoubiquitination of Histone H2B Is Intrinsic to the Bre1 RING Domain-Rad6 Interaction and Augmented by a Second Rad6-binding Site on Bre1
Published in The Journal of biological chemistry (27-02-2015)“…Ubiquitin signaling on chromatin is linked to diverse aspects of genome regulation, including gene expression and DNA repair. The yeast RING E3 ligase Bre1…”
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Protein compactness and interaction valency define the architecture of a biomolecular condensate across scales
Published in eLife (20-07-2023)“…Non-membrane-bound biomolecular condensates have been proposed to represent an important mode of subcellular organization in diverse biological settings…”
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Single-cell trapping and selective treatment via co-flow within a microfluidic platform
Published in Biosensors & bioelectronics (15-11-2014)“…Lab on a chip (LOC) systems provide interesting and low-cost solutions for key studies and applications in the biomedical field. Along with microfluidics,…”
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Scalable haloscopes for axion dark matter detection in the 30 μeV range with RADES
Published in The journal of high energy physics (01-07-2020)“…A bstract RADES (Relic Axion Detector Exploratory Setup) is a project with the goal of directly searching for axion dark matter above the 30 μ eV scale…”
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Failure mechanisms in unirradiated ZIRLO® cladding with radial hydrides
Published in Journal of nuclear materials (01-02-2021)“…•Radial hydride metrics is not the only parameter for cladding failure•Crack nucleation occurs in radial hydrides at regions with highest hoop stress•The…”
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Hydrogen sulphide as a signalling molecule regulating physiopathological processes in gastrointestinal motility
Published in British journal of pharmacology (01-09-2017)“…The biology of H2S is a still developing area of research and several biological functions have been recently attributed to this gaseous molecule in many…”
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Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility
Published in British journal of pharmacology (01-09-2011)“…BACKGROUND AND PURPOSE The role of hydrogen sulphide (H2S) as a putative endogenous signalling molecule in the gastrointestinal tract has not yet been…”
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Non-viral reprogramming of human nucleus pulposus cells with FOXF1 via extracellular vesicle delivery: an in vitro and in vivo study
Published in European cells & materials (19-01-2021)“…Intervertebral disc (IVD) degeneration is characterized by decreased cellularity and proteoglycan synthesis and increased inflammation, catabolism, and…”
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Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6–Bre1
Published in Proceedings of the National Academy of Sciences - PNAS (20-09-2016)“…Cotranscriptional ubiquitination of histone H2B is key to gene regulation. The yeast E3 ubiquitin ligase Bre1 (human RNF20/40) pairs with the E2 ubiquitin…”
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The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore
Published in eLife (21-05-2019)“…Kinetochores are macromolecular protein complexes at centromeres that ensure accurate chromosome segregation by attaching chromosomes to spindle microtubules…”
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Imbalanced classification techniques for monsoon forecasting based on a new climatic time series
Published in Environmental modelling & software : with environment data news (01-08-2018)“…Monsoons have been widely studied in the literature due to their climatic impact related to precipitation and temperature over different regions around the…”
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Proteostasis regulators as potential rescuers of PMM2 activity
Published in Biochimica et biophysica acta. Molecular basis of disease (01-07-2020)“…Phosphomannomutase 2 deficiency (PMM2-CDG) is the most common N-glycosylation disorder. To date there is no treatment. Following the identification of a number…”
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Climate tolerances of Philaenus spumarius should be considered in risk assessment of disease outbreaks related to Xylella fastidiosa
Published in Journal of pest science (01-03-2022)“…The bacterium Xylella fastidiosa ( Xf ) is an invasive insect-borne pathogen, which causes lethal diseases to important crops including olives, citrus, almonds…”
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Optimization of traps for live trapping of Pine Wood Nematode vector Monochamus galloprovincialis
Published in Journal of applied entomology (1986) (01-09-2015)“…The pine sawyer beetle Monochamus galloprovincialis, a secondary pest of pines in Europe and North Africa, has become important as it was identified as the…”
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[Translated article] Influence of lateralized reverse shoulder prosthesis design on tuberosity union in proximal humerus fractures
Published in Revista española de cirugía ortopédica y traumatología (01-05-2023)“…Proximal humerus fractures are the third most frequent type of fracture in elderly patients. Nowadays, surgical treatment is indicated one third of the time,…”
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The Impact of Revascularization Surgery on Headaches in Association with Cerebrovascular Reactivity in Patients with Moyamoya Angiopathy
Published in Brain sciences (26-09-2024)“…Headaches in Moyamoya angiopathy are common but poorly understood. We aimed to investigate if headaches in Moyamoya angiopathy improve after revascularization…”
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[Translated article] Influence of lateralized reverse shoulder prosthesis design on tuberosity union in proximal humerus fractures
Published in Revista española de cirugía ortopédica y traumatología (01-05-2023)“…Proximal humerus fractures are the third most frequent type of fracture in elderly patients. Nowadays, surgical treatment is indicated one third of the time,…”
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Potential role of the gaseous mediator hydrogen sulphide (H2S) in inhibition of human colonic contractility
Published in Pharmacological research (01-03-2015)“…Hydrogen sulphide (H2S) is an endogenous signalling molecule that might play a physiologically relevant role in gastrointestinal motility. Cystathionine…”
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