Search Results - "Gallant, Nathan D"

Crosslinking effect on polydimethylsiloxane elastic modulus measured by custom-built compression instrument by Wang, Zhixin, Volinsky, Alex A., Gallant, Nathan D.

“…ABSTRACT A macroscopic compression test utilizing a simple custom‐built instrument was employed to measure polydimethylsiloxane (PDMS) elastic modulus. PDMS…”
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Regulation of Cell Adhesion Strength by Peripheral Focal Adhesion Distribution by Elineni, Kranthi Kumar, Gallant, Nathan D.

“…Cell adhesion to extracellular matrices is a tightly regulated process that involves the complex interplay between biochemical and mechanical events at the…”
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Nanoindentation study of polydimethylsiloxane elastic modulus using Berkovich and flat punch tips by Wang, Zhixin, Volinsky, Alex A., Gallant, Nathan D.

“…ABSTRACT This article explores polydimethylsiloxane (PDMS) mechanical properties, and presents nanoindentation experiments with Berkovich and flat punch…”
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Sheathless size-based acoustic particle separation by Guldiken, Rasim, Jo, Myeong Chan, Gallant, Nathan D, Demirci, Utkan, Zhe, Jiang

“…Particle separation is of great interest in many biological and biomedical applications. Flow-based methods have been used to sort particles and cells…”
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Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients by Moore, Nicole M., Lin, Nancy J., Gallant, Nathan D., Becker, Matthew L.

“…Rational design of bioactive tissue engineered scaffolds for directing bone regeneration in vivo requires a comprehensive understanding of cell interactions…”
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Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly by Gallant, Nathan D, Michael, Kristin E, García, Andrés J

“…Mechanical interactions between a cell and its environment regulate migration, contractility, gene expression, and cell fate. We integrated micropatterned…”
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Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve by Damaghi, Mehdi, Mori, Hidetoshi, Byrne, Samantha, Xu, Liping, Chen, Tingan, Johnson, Joseph, Gallant, Nathan D., Marusyk, Andriy, Borowsky, Alexander D., Gillies, Robert J.

“…Growing tumors are dynamic and nonlinear ecosystems, wherein cancer cells adapt to their local microenvironment, and these adaptations further modify the…”
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Contractility modulates cell adhesion strengthening through focal adhesion kinase and assembly of vinculin-containing focal adhesions by Dumbauld, David W., Shin, Heungsoo, Gallant, Nathan D., Michael, Kristin E., Radhakrishna, Harish, García, Andrés J.

“…Actin–myosin contractility modulates focal adhesion assembly, stress fiber formation, and cell migration. We analyzed the contributions of contractility to…”
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A urinary Bcl-2 surface acoustic wave biosensor for early ovarian cancer detection by Onen, Onursal, Sisman, Alper, Gallant, Nathan D, Kruk, Patricia, Guldiken, Rasim

“…In this study, the design, fabrication, surface functionalization and experimental characterization of an ultrasonic MEMS biosensor for urinary anti-apoptotic…”
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Surface modification on acoustic wave biosensors for enhanced specificity by Onen, Onursal, Ahmad, Asad A, Guldiken, Rasim, Gallant, Nathan D

“…Changes in mass loading on the surface of acoustic biosensors result in output frequency shifts which provide precise measurements of analytes. Therefore, to…”
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Effect of nordihydroguaiaretic acid cross-linking on fibrillar collagen: in vitro evaluation of fibroblast adhesion strength and migration by Y. Rioja, Ana, Muniz-Maisonet, Maritza, J. Koob, Thomas, D. Gallant, Nathan

“…Fixation is required to reinforce reconstituted collagen for orthopedic bioprostheses such as tendon or ligament replacements. Previous studies have…”
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Comparison of the macroscale and microscale tests for measuring elastic properties of polydimethylsiloxane by Sharfeddin, Asma, Volinsky, Alex A., Mohan, Greeshma, Gallant, Nathan D.

“…ABSTRACT Polydimethylsiloxane (PDMS) has many biomedical applications, since it is biocompatible, easy to fabricate and inexpensive. The response of biological…”
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A combinatorial approach to protect sensory tissue against cisplatin-induced ototoxicity by Febles, Nicole K., Bauer, Mark A., Ding, Bo, Zhu, Xiaoxia, Gallant, Nathan D., Frisina, Robert D.

“…•A combinatorial approach to prevent cisplatin ototoxicity was investigated.•It consisted of an antioxidant, neurotrophin and anti-apoptotic.•This therapy…”
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Responsive coatings from naturally occurring pectin polysaccharides by Veisi, Zeinab, Gallant, Nathan D., Alcantar, Norma A., Toomey, Ryan G.

“…[Display omitted] •Thin coatings of highly esterified pectin cross-linked with calcium in ethanol.•Pectin films display thermally-responsive swelling behavior…”
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Laser machined micropatterns as corrosion protection of both hydrophobic and hydrophilic magnesium by Yayoglu, Yahya Efe, Toomey, Ryan G., Crane, Nathan B., Gallant, Nathan D.

“…Magnesium and its alloys are promising candidate materials for medical implants because they possess excellent biocompatibility and mechanical properties…”
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Surface chemistry gradients on silicone elastomers for high-throughput modulation of cell-adhesive interfaces by Mohan, Greeshma, Gallant, Nathan D.

“…Combinatorial and high‐throughput approaches to screening cell responses to material properties accelerate the speed of discovery and facilitate the…”
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A Cell ELISA for the quantification of MUC1 mucin (CD227) expressed by cancer cells of epithelial and neuroectodermal origin by Falahat, Rana, Wiranowska, Marzenna, Gallant, Nathan D., Toomey, Ryan, Hill, Robert, Alcantar, Norma

“…•Cell ELISA is a sensitive method for quantification of cell surface antigens.•We developed a Cell ELISA assay for quantification of MUC1.•Cell ELISA in live…”
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Mechanical characterization of crosslinking effect in polydimethylsiloxane using nanoindentation by Jin, Congrui, Wang, Zhixin, Volinsky, Alex A., Sharfeddin, Asma, Gallant, Nathan D.

“…Polydimethylsiloxane (PDMS) is one of the widely-used silicone-based organic polymers. It can serve as a substrate to grow cells, mainly because of its…”
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Protein-surface interactions on stimuli-responsive polymeric biomaterials by Cross, Michael C, Toomey, Ryan G, Gallant, Nathan D

“…Responsive surfaces: a review of the dependence of protein adsorption on the reversible volume phase transition in stimuli-responsive polymers. Specifically…”
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The use of immobilized osteogenic growth peptide on gradient substrates synthesized via click chemistry to enhance MC3T3-E1 osteoblast proliferation by Moore, Nicole M, Lin, Nancy J, Gallant, Nathan D, Becker, Matthew L

“…Abstract In this study, we report the use of surface immobilized peptide concentration gradient technology to characterize MC3T3-E1 osteoblast cell response to…”
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