Search Results - "Gallagher, Robert E"

Single Cycle of Arsenic Trioxide–Based Consolidation Chemotherapy Spares Anthracycline Exposure in the Primary Management of Acute Promyelocytic Leukemia by GORE, Steven D, GOJO, Ivana, SCHACHTER-TOKARZ, Esther, GALLAGHER, Robert E, SEKERES, Mikkael A, MORRIS, Lawrence, DEVETTEN, Marcel, JAMIESON, Katarzyna, REDNER, Robert L, ARCECI, Robert, OWOEYE, Ibitayo, DAUSES, Tianna

“…PURPOSE Event-free survival following all-trans-retinoic acid (ATRA) -based therapy for acute promyelocytic leukemia (APL) averages 70% at 5 years. While…”
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Molecular Load of Pathologically Occult Metastases in Pelvic Lymph Nodes Is an Independent Prognostic Marker of Biochemical Failure After Localized Prostate Cancer Treatment by FERRARI, Anna C, STONE, Nelson N, HALL, Simon, RENNEBERG, Heiner, LIVAK, Kenneth J, GALLAGHER, Robert E, MANDELI, John, KUREK, Ralf, MULLIGAN, Elizabeth, MCGREGOR, Roy, STOCK, Richard, UNGER, Pamela, TUNN, Ulf, KAISARY, Amir, DROLLER, Michael

“…Thirty percent of patients treated with curative intent for localized prostate cancer (PC) experience biochemical recurrence (BCR) with rising serum…”
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Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia by Patel, Jay P, Gönen, Mithat, Figueroa, Maria E, Fernandez, Hugo, Sun, Zhuoxin, Racevskis, Janis, Van Vlierberghe, Pieter, Dolgalev, Igor, Thomas, Sabrena, Aminova, Olga, Huberman, Kety, Cheng, Janice, Viale, Agnes, Socci, Nicholas D, Heguy, Adriana, Cherry, Athena, Vance, Gail, Higgins, Rodney R, Ketterling, Rhett P, Gallagher, Robert E, Litzow, Mark, van den Brink, Marcel R.M, Lazarus, Hillard M, Rowe, Jacob M, Luger, Selina, Ferrando, Adolfo, Paietta, Elisabeth, Tallman, Martin S, Melnick, Ari, Abdel-Wahab, Omar, Levine, Ross L

“…Malignant cells in most patients with acute myeloid leukemia have mutations. Cytogenetic classification yields some prognostic information, but the…”
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Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710 by Powell, Bayard L., Moser, Barry, Stock, Wendy, Gallagher, Robert E., Willman, Cheryl L., Stone, Richard M., Rowe, Jacob M., Coutre, Steven, Feusner, James H., Gregory, John, Couban, Stephen, Appelbaum, Frederick R., Tallman, Martin S., Larson, Richard A.

“…Arsenic trioxide (As2O3) is a highly effective treatment for patients with relapsed acute promyelocytic leukemia (APL); its role as consolidation treatment for…”
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Real-time consensus on relapse risk in acute promyelocytic leukemia by Gallagher, Robert E., M.D

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Mutants strike again in APL by Gallagher, Robert E.

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Arsenic trioxide in front-line therapy of acute promyelocytic leukemia (C9710): prognostic significance of FLT3 mutations and complex karyotype by Poiré, Xavier, Moser, Barry K., Gallagher, Robert E., Laumann, Kristina, Bloomfield, Clara D., Powell, Bayard L., Koval, Gregory, Gulati, Kabir, Holowka, Nicholas, Larson, Richard A., Tallman, Martin S., Appelbaum, Frederick R., Sher, Dorie, Willman, Cheryl, Paietta, Elisabeth, Stock, Wendy

“…Abstract The addition of arsenic trioxide (ATO) to frontline therapy of acute promyelocytic leukemia (APL) has been shown to result in significant improvements…”
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Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia by Werner, Benjamin, Gallagher, Robert E, Paietta, Elisabeth M, Litzow, Mark R, Tallman, Martin S, Wiernik, Peter H, Slack, James L, Willman, Cheryl L, Sun, Zhuoxin, Traulsen, Arne, Dingli, David

“…Many tumors are believed to be maintained by a small number of cancer stem-like cells, where cure is thought to require eradication of this cell population. In…”
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Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia by Gallagher, Robert E., Moser, Barry K., Racevskis, Janis, Poiré, Xavier, Bloomfield, Clara D., Carroll, Andrew J., Ketterling, Rhett P., Roulston, Diane, Schachter-Tokarz, Esther, Zhou, Da-cheng, Chen, I-Ming L., Harvey, Richard, Koval, Greg, Sher, Dorie A., Feusner, James H., Tallman, Martin S., Larson, Richard A., Powell, Bayard L., Appelbaum, Frederick R., Paietta, Elisabeth, Willman, Cheryl L., Stock, Wendy

“…Mutations in the all-trans retinoic acid (ATRA)–targeted ligand binding domain of PML-RARα (PRα/LBD+) have been implicated in the passive selection of…”
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KLF6 Loss of Function in Human Prostate Cancer Progression Is Implicated in Resistance to Androgen Deprivation by Liu, XiaoMei, Gomez-Pinillos, Alejandro, Loder, Charisse, Carrillo-de Santa Pau, Enrique, Qiao, Ruifang, Unger, Pamela D, Kurek, Ralf, Oddoux, Carole, Melamed, Jonathan, Gallagher, Robert E, Mandeli, John, Ferrari, Anna C

“…Inactivation of the transcription factor/tumor suppressor Krüppel-like factor 6 (KLF6) has been described in prostate cancer (PC). This study investigated the…”
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All-trans retinoic acid and late relapses in acute promyelocytic leukemia: Very long-term follow-up of the North American Intergroup Study I0129 by Douer, Dan, Zickl, Lynette N, Schiffer, Charles A, Appelbaum, Fredrick R, Feusner, James H, Shepherd, Lois, Willman, Cheryl L, Bloomfield, Clara D, Paietta, Elisabeth, Gallagher, Robert E, Park, Jae H, Rowe, Jacob M, Wiernik, Peter H, Tallman, Martin S

“…Abstract We report a long-term follow-up (median 11.8 years) of the First North American Intergroup Study. 379 patients were randomized to induction with ATRA…”
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SCANning for PML nuclear bodies with Myeloid Zinc Finger 1 by Gallagher, Robert E

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Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia by Baljevic, Muhamed, Dumitriu, Bogdan, Lee, Ju-Whei, Paietta, Elisabeth M, Wiernik, Peter H, Racevskis, Janis, Chen, Christina, Stein, Eytan M, Gallagher, Robert E, Rowe, Jacob M, Appelbaum, Frederick R, Powell, Bayard L, Larson, Richard A, Coutré, Steven E, Lancet, Jeffrey, Litzow, Mark R, Luger, Selina M, Young, Neal S, Tallman, Martin S

“…Telomeres are the capping ends of chromosomes that protect the loss of genetic material and prevent chromosomal instability. In human tissue-specific…”
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Quantitative real-time RT-PCR analysis of PML-RARα mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129 by Gallagher, Robert E., Yeap, Beow Y., Bi, Wanli, Livak, Kenneth J., Beaubier, Nike, Rao, Sreenivas, Bloomfield, Clara D., Appelbaum, Frederick R., Tallman, Martin S., Slack, James L., Willman, Cheryl L.

“…The potential prognostic value of quantitative real-time reverse transcription–polymerase chain reaction (RT-PCR [qrtPCR]) measurements of PML-RARα mRNA in…”
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Frequent mutations in the ligand-binding domain of PML-RARα after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo by ZHOU, Da-Cheng, KIM, Soon H, WEI DING, SCHULTZ, Cynthia, WARRELL, Raymond P, GALLAGHER, Robert E

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture by COLLINS, STEVEN J, GALLO, ROBERT C, GALLAGHER, ROBERT E

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Arsenic — New Life for an Old Potion by Gallagher, Robert E

“…One of our gentlemen found time to say `How delicious!'” declares Aunt Abby to a mortified Mortimer after he discovers a corpse in the 1944 movie classic…”
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Altered ligand binding and transcriptional regulation by mutations in the PML/RARα ligand-binding domain arising in retinoic acid–resistant patients with acute promyelocytic leukemia by Côté, Sylvie, Zhou, Dacheng, Bianchini, Andrea, Nervi, Clara, Gallagher, Robert E., Miller, Wilson H.

“…Acute promyelocytic leukemia (APL) is characterized by a specific translocation, t(15;17), that fuses the promyelocytic leukemia (PML) gene with the RA…”
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A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia by Litzow, MR, Lee, S, Bennett, JM, Dewald, GW, Gallagher, RE, Jain, V, Paietta, EM, Racevskis, J, Rousey, , SR, Mazza, JJ, Tallman, MS

“…Division of Hematology, Mayo Clinic College of Medicine, 200 First St. S.W., Rochester, MN 55905, USA. litzow.mark@mayo.edu We designed a phase II trial of…”
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United States Civil Reserve Air Fleet (CRAF): A Brief History—Formation, Functionality, and Future by Gallagher, Robert E., Burch, Gerald F., Batchelor, John H.

“…Air mobility has been a military strategic advantage used by the United States (U.S.) from the onset of aircraft carriers, to supporting air bases worldwide…”
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