Search Results - "Gallagher, Jane E"

Factors associated with self-reported health: implications for screening level community-based health and environmental studies by Gallagher, Jane E, Wilkie, Adrien A, Cordner, Alissa, Hudgens, Edward E, Ghio, Andrew J, Birch, Rebecca J, Wade, Timothy J

“…Advocates for environmental justice, local, state, and national public health officials, exposure scientists, need broad-based health indices to identify…”
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Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes by Williams-DeVane, Clarlynda R, Reif, David M, Hubal, Elaine Cohen, Bushel, Pierre R, Hudgens, Edward E, Gallagher, Jane E, Edwards, Stephen W

“…Complex diseases are often difficult to diagnose, treat and study due to the multi-factorial nature of the underlying etiology. Large data sets are now widely…”
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Data-driven asthma endotypes defined from blood biomarker and gene expression data by George, Barbara Jane, Reif, David M, Gallagher, Jane E, Williams-DeVane, ClarLynda R, Heidenfelder, Brooke L, Hudgens, Edward E, Jones, Wendell, Neas, Lucas, Hubal, Elaine A Cohen, Edwards, Stephen W

“…The diagnosis and treatment of childhood asthma is complicated by its mechanistically distinct subtypes (endotypes) driven by genetic susceptibility and…”
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Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population by Joubert, Bonnie R, Reif, David M, Edwards, Stephen W, Leiner, Kevin A, Hudgens, Edward E, Egeghy, Peter, Gallagher, Jane E, Hubal, Elaine Cohen

“…Asthma and allergy represent complex phenotypes, which disproportionately burden ethnic minorities in the United States. Strong evidence for genomic factors…”
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Effects of Storage, RNA Extraction, Genechip Type, and Donor Sex on Gene Expression Profiling of Human Whole Blood by Kim, Sung Jae, Dix, David J, Thompson, Kary E, Murrell, Rachel N, Schmid, Judith E, Gallagher, Jane E, Rockett, John C

“…Gene expression profiling of whole blood may be useful for monitoring toxicological exposure and for diagnosis and monitoring of various diseases. Several…”
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Air Pollution Particles Mediated Oxidative DNA Base Damage in a Cell Free System and in Human Airway Epithelial Cells in Relation to Particulate Metal Content and Bioreactivity by Prahalad, Agasanur K, Inmon, Jeff, Dailey, Lisa A, Madden, Michael C, Ghio, Andrew J, Gallagher, Jane E

“…Epidemiological studies demonstrate an association between increased human morbidity and mortality with exposure to air pollution particulate matter. We…”
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Allergens in Household Dust and Serological Indicators of Atopy and Sensitization in Detroit Children with History-Based Evidence of Asthma by Williams, Ann Houston, Smith, James Travis, Hudgens, Edward E., Rhoney, Scott, Özkaynak, Halûk, Hamilton, Robert G., Gallagher, Jane E

“…Background. Home exposure to allergens is an important factor in the development of sensitization and subsequent exacerbations of allergic asthma. We…”
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Gender and Racial/Ethnic Disparities: Cumulative Screening of Health Risk Indicators in 20-50 Year Olds in the United States by Cordner, Alissa, Wilkie, Adrien A, Wade, Timothy J, Hudgens, Edward E, Birch, Rebecca J, Gallagher, Jane E

“…This study explored potential gender and racial/ethnic disparities in overall health risk related to 24 health risk indicators selected across six domains:…”
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Comparative Microarray Analysis and Pulmonary Changes in Brown Norway Rats Exposed to Ovalbumin and Concentrated Air Particulates by Heidenfelder, Brooke L., Reif, David M., Harkema, Jack R., Cohen Hubal, Elaine A., Hudgens, Edward E., Bramble, Lori A., Wagner, James G., Morishita, Masako, Keeler, Gerald J., Edwards, Stephen W., Gallagher, Jane E.

“…The interaction between air particulates and genetic susceptibility has been implicated in the pathogenesis of asthma. The overall objective of this study was…”
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Ambient Air Particles: Effects on Cellular Oxidant Radical Generation in Relation to Particulate Elemental Chemistry by Prahalad, Agasanur K., Soukup, Joleen M., Inmon, Jefferson, Willis, Robert, Ghio, Andrew J., Becker, Susanne, Gallagher, Jane E.

“…Epidemiologic studies have reported causal relationships between exposures to high concentrations of ambient air particles (AAP) and increased morbidity in…”
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Increased Plasma Reactive Oxidant Levels and Their Relationship to Blood Cells, Total IgE, and Allergen-specific IgE Levels in Asthmatic Children by Heidenfelder, Brooke, Johnson, Markey, Hudgens, Edward, Inmon, Jefferson, Hamilton, Robert G, Neas, Lucas, Gallagher, Jane E.

“…Asthma is a disorder characterized by inflammation of the airways. Oxidative stress may play a role in the pathophysiology of several diseases including…”
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Increased Plasma Reactive Oxidant Levels and Their Relationship to Blood Cells, Total IgE, and Allergen-specific IgE Levels in Asthmatic Children by Heidenfelder, Brooke, Johnson, Markey, Hudgens, Edward, Inmon, Jefferson, Hamilton, Robert G, Neas, Lucas, Gallagher, Jane E.

“…Asthma is a disorder characterized by inflammation of the airways. Oxidative stress may play a role in the pathophysiology of several diseases including…”
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Enhancement of 2‘-Deoxyguanosine Hydroxylation and DNA Damage by Coal and Oil Fly Ash in Relation to Particulate Metal Content and Availability by Prahalad, Agasanur K, Inmon, Jeff, Ghio, Andrew J, Gallagher, Jane E

“…Epidemiologic studies have shown causal relationships between air pollution particles and adverse health effects in susceptible subpopulations. Fly ash…”
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Gene expression in head hair follicles plucked from men and women by Kim, Sung Jae, Dix, David J, Thompson, Kary E, Murrell, Rachel N, Schmid, Judith E, Gallagher, Jane E, Rockett, John C

“…Characterizing gene expression in hair follicles can help to elucidate the hair growth cycle by delineating the genes and pathways involved in follicular…”
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Separation of 32P-Postlabeled DNA Adducts of Polycyclic Aromatic Hydrocarbons and Nitrated Polycyclic Aromatic Hydrocarbons by HPLC by King, Leon C, George, Michael, Gallagher, Jane E, Lewtas, Joellen

“…The 32P-postlabeling assay, thin-layer chromatography, and reverse-phase high-pressure liquid chromatography (HPLC) were used to separate DNA adducts formed…”
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Data-Driven Asthma Endotypes Defined from Blood Biomarker and Gene Expression Data: e0117445 by George, Barbara Jane, Reif, David M, Gallagher, Jane E, Williams-DeVane, ClarLynda R, Heidenfelder, Brooke L, Hudgens, Edward E, Jones, Wendell, Neas, Lucas, Hubal, Elaine ACohen, Edwards, Stephen W

“…The diagnosis and treatment of childhood asthma is complicated by its mechanistically distinct subtypes (endotypes) driven by genetic susceptibility and…”
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Multiple DNA adducts in lymphocytes of smokers and nonsmokers determined by 32P-postlabeling analysis by Jahnke, G D, Thompson, C L, Walker, M P, Gallagher, J E, Lucier, G W, DiAugustine, R P

“…Identification of DNA adducts in peripheral lymphocytes could serve as a means of monitoring human exposure to potential genotoxic agents. In this study, DNA…”
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Toxicological Significance of DNA Adducts: Summary of Discussions with an Expert Panel by Nestmann, Earle R., Bryant, Douglas W., Carr, C.Jelleff, Fennell, Timothy T., Gallagher, Jane E., Gorelick, Nancy J., Swenberg, James A., Williams, Gary M.

“…A workshop was held to discuss the uses of data on DNA adduct measurement in humans and in experimental systemsin vitroandin vivo.The discussions focused…”
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Diazepam versus midazolam for colonoscopy: a prospective evaluation of predicted versus actual dosing requirements by Ginsberg, G G, Lewis, J H, Gallagher, J E, Fleischer, D E, al-Kawas, F H, Nguyen, C C, Mundt, D J, Benjamin, S B

“…We performed a prospective, randomized, double-blind study to evaluate the efficacy of the currently recommended low doses of midazolam for conscious sedation…”
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Improvement in the diagnostic potential of 32P-postlabeling analysis demonstrated by the selective formation and comparative analysis of nitrated-PAH-derived adducts arising from diesel particle extracts by Gallagher, J E, Kohan, M J, George, M H, Lewtas, J

“…Two versions of the 32P-postlabeling assay (nuclease P1 and butanol extraction) enhance the detection limit of polycyclic aromatic hydrocarbon (PAH)-modified…”
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