Search Results - "Gall, Walter E."
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Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
Published in PloS one (11-11-2010)“…Metabolomics is the rapidly evolving field of the comprehensive measurement of ideally all endogenous metabolites in a biological fluid. However, no single…”
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alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population
Published in PloS one (28-05-2010)“…Insulin resistance is a risk factor for type 2 diabetes and cardiovascular disease progression. Current diagnostic tests, such as glycemic indicators, have…”
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3
Kinetochore Microtubule Dynamics and Attachment Stability Are Regulated by Hec1
Published in Cell (01-12-2006)“…Mitotic cells face the challenging tasks of linking kinetochores to growing and shortening microtubules and actively regulating these dynamic attachments to…”
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Drs2p-Dependent Formation of Exocytic Clathrin-Coated Vesicles In Vivo
Published in Current biology (17-09-2002)“…The small GTP binding protein ARF has been implicated in budding clathrin-coated vesicles (CCVs) from Golgi and endosomal membranes. An arf1 synthetic lethal…”
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Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance
Published in Diabetes (New York, N.Y.) (01-05-2013)“…Metabolomic screening of fasting plasma from nondiabetic subjects identified α-hydroxybutyrate (α-HB) and linoleoyl-glycerophosphocholine (L-GPC) as joint…”
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Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7
Published in The Journal of steroid biochemistry and molecular biology (01-07-1999)“…In this work, UDP-glucuronosyltransferases (UGTs), UGT1A3, 2B7(H268) and 2B7(Y268), stably expressed in human embryonic kidney cells (HK293) were used to…”
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Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2013)“…Circulating metabolites associated with insulin sensitivity may represent useful biomarkers, but their causal role in insulin sensitivity and diabetes is less…”
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The auxilin-like phosphoprotein Swa2p is required for clathrin function in yeast
Published in Current biology (02-11-2000)“…Background: In eukaryotic cells, clathrin-coated vesicles transport specific cargo from the plasma membrane and trans-Golgi network to the endosomal system…”
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4-Hydroxyretinoic Acid, a Novel Substrate for Human Liver Microsomal UDP-glucuronosyltransferase(s) and Recombinant UGT2B7
Published in The Journal of biological chemistry (10-03-2000)“…It is suggested that formation of more polar metabolites of all-trans-retinoic acid (atRA) via oxidative pathways limits its biological activity. In this…”
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Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae
Published in Proteins, structure, function, and bioinformatics (01-03-2004)“…The SWA2/AUX1 gene has been proposed to encode the Saccharomyces cerevisiae ortholog of mammalian auxilin. Swa2p is required for clathrin assembly/dissassembly…”
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Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population
Published in PloS one (28-05-2010)“…Background Insulin resistance is a risk factor for type 2 diabetes and cardiovascular disease progression. Current diagnostic tests, such as glycemic…”
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12
Application of photoaffinity labeling with [3H] all trans‐ and 9‐cis‐retinoic acids for characterization of cellular retinoic acid–binding proteins I and II
Published in Protein science (01-01-2001)“…Cellular retinoic acid–binding proteins (CRABPs) are carrier proteins thought to play a crucial role in the transport and metabolism of all‐trans‐retinoic acid…”
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