Search Results - "Gall, Irene"

β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi by Baillie, George S, Sood, Arvind, McPhee, Ian, Gall, Irene, Perry, Stephen J, Lefkowitz, Robert J, Houslay, Miles D

“…Phosphorylation of the β 2 adrenoreceptor (β 2 AR) by cAMP-activated protein kinase A (PKA) switches its predominant coupling from stimulatory guanine…”
Get full text

Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells by STEFAN, Eduard, WIESNER, Burkhard, BEYERMANN, Michael, KRAUSE, Eberhard, POHL, Peter, GALL, Irene, MACINTYRE, Andrew N, BACHMANN, Sebastian, HOUSLAY, Miles D, ROSENTHAL, Walter, KLUSSMANN, Enno, BAILLIE, George S, MOLLAJEW, Rustam, HENN, Volker, LORENZ, Dorothea, FURKERT, Jens, SANTAMARIA, Katja, NEDVETSKY, Pavel, HUNDSRUCKER, Christian

“…The cAMP/protein kinase A (PKA)-dependent insertion of water channel aquaporin-2 (AQP2)-bearing vesicles into the plasma membrane in renal collecting duct…”
Get full text

Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2 by Huston, Elaine, Gall, Irene, Houslay, Thomas M, Houslay, Miles D

“…The unique N-terminal regions of PDE4 cAMP-specific phosphodiesterases confer interaction with distinct signalling and scaffolding proteins. The PDE4A1 isoform…”
Get full text

PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6) by Cheung, York-Fong, Kan, Zhengyan, Garrett-Engele, Philip, Gall, Irene, Murdoch, Hannah, Baillie, George S, Camargo, Luiz Miguel, Johnson, Jason M, Houslay, Miles D, Castle, John C

“…The cAMP-specific phosphodiesterase-4 (PDE4) gene family is the target of several potential selective therapeutic inhibitors. The four PDE4 genes generate…”
Get more information

Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene by Wallace, Derek A, Johnston, Lee Ann, Huston, Elaine, MacMaster, Douglas, Houslay, Thomas M, Cheung, York-Fong, Campbell, Lachlan, Millen, Jenni E, Smith, Robin A, Gall, Irene, Knowles, Richard G, Sullivan, Michael, Houslay, Miles D

“…PDE4A11 is a novel cAMP-specific phosphodiesterase that is conserved in humans, mouse, rat, pig, and bat. Exon-1(4A11) encodes its unique, 81 amino acid…”
Get more information

In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting by Beard, Matthew B, Huston, Elaine, Campbell, Lachlan, Gall, Irene, McPhee, Ian, Yarwood, Stephen, Scotland, Grant, Houslay, Miles D

“…The long cyclic AMP (cAMP)-specific phosphodiesterase isoform, PDE4A5 (PDE4A subfamily isoform variant 5), when transiently expressed in COS-7 cells, was shown…”
Get full text

TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid by Baillie, George S., Huston, Elaine, Scotland, Grant, Hodgkin, Matt, Gall, Irene, Peden, Alex H., MacKenzie, Carolynn, Houslay, Emma S., Currie, Richard, Pettitt, Trevor R., Walmsley, Adrian R., Wakelam, Michael J.O., Warwicker, Jim, Houslay, Miles D.

“…Here we identify an 11-residue helical module in the unique N-terminal region of the cyclic AMP-specific phosphodiesterase PDE4A1 that determines association…”
Get full text

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region by McCahill, Angela, McSorley, Theresa, Huston, Elaine, Hill, Elaine V., Lynch, Martin J., Gall, Irene, Keryer, Guy, Lygren, Birgitte, Tasken, Kjetil, van Heeke, Gino, Houslay, Miles D.

“…We employ a novel, dominant negative approach to identify a key role for certain tethered cyclic AMP specific phosphodiesterase-4 (PDE4) isoforms in regulating…”
Get full text

Oxidative stress employs phosphatidyl inositol 3-kinase and ERK signalling pathways to activate cAMP phosphodiesterase-4D3 (PDE4D3) through multi-site phosphorylation at Ser239 and Ser579 by Hill, Elaine V., Sheppard, Catherine L., Cheung, York-Fong, Gall, Irene, Krause, Eberhard, Houslay, Miles D.

“…RAW macrophages, which express the PDE4D3 and PDE4D5 cAMP phosphodiesterase isoforms, exhibited increased PDE4 activity when challenged with H 2O 2 in a…”
Get full text

Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca super(2+) by Huston, Elaine, Gall, Irene, Houslay, Thomas M, Houslay, Miles D

“…The unique N-terminal regions of PDE4 cAMP-specific phosphodiesterases confer interaction with distinct signalling and scaffolding proteins. The PDE4A1 isoform…”
Get full text

Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process by Terry, Robert, Cheung, York-Fong, Praestegaard, Morten, Baillie, George S., Huston, Elaine, Gall, Irene, Adams, David R., Houslay, Miles D.

“…In cells transfected to express wild-type PDE4A4 cAMP phosphodiesterase (PDE), the PDE4 selective inhibitor rolipram caused PDE4A4 to relocalise so as to form…”
Get full text

β-Arrestin-Mediated PDE4 cAMP Phosphodiesterase Recruitment Regulates β-Adrenoceptor Switching from Gsto Gi by Baillie, George S., Sood, Arvind, McPhee, Ian, Gall, Irene, Perry, Stephen J., Lefkowitz, Robert J., Houslay, Miles D.

“…Phosphorylation of the β2adrenoreceptor (β2AR) by cAMP-activated protein kinase A (PKA) switches its predominant coupling from stimulatory guanine nucleotide…”
Get full text

RETRACTED: β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from G s to G i by Baillie, George S., Sood, Arvind, McPhee, Ian, Gall, Irene, Perry, Stephen J., Lefkowitz, Robert J., Houslay, Miles D.

“…Phosphorylation of the β 2 adrenoreceptor (β 2 AR) by cAMP-activated protein kinase A (PKA) switches its predominant coupling from stimulatory guanine…”
Get full text

Mouse cytoskeletal gamma-actin: analysis and implications of the structure of cloned cDNA and processed pseudogenes by Peter, B, Man, Y M, Begg, C E, Gall, I, Leader, D P

“…The nucleotide sequence corresponding to almost the whole of a mouse gamma-cytoskeletal actin mRNA was determined from overlapping cloned DNA copies derived…”
Get more information

The structure of a cloned mouse gamma-actin processed pseudogene by Leader, D P, Gall, I, Lehrach, H

“…The complete nucleotide (nt) sequence of a gamma-actin-like pseudogene (M gamma A-psi 1), isolated from a mouse genomic library in phage lambda, was…”
Get more information

Complexation on rhodium of bidentate and potentially hemilabile phosphorous ligands by Le Gall, Irène, Laurent, Pascale, Soulier, Eric, Salaün, Jean-Yves, des Abbayes, Hervé

“…Various bifunctional potentially hemilabile ligands bearing phosphorous groups have been prepared and their coordination to rhodium has been studied. Their…”
Get full text

The structure of a cDNA clone corresponding to mouse cardiac muscle actin mRNA by Leader, D P, Gall, I, Campbell, P C

“…A cDNA library was constructed from mouse cardiac muscle mRNA, and a clone corresponding to part of the mRNA for the cardiac muscle isoform of actin was…”
Get more information

Isolation and characterization of cDNA clones from mouse skeletal muscle actin mRNA by Leader, D P, Gall, I, Campbell, P, Frischauf, A M

“…The sequence corresponding to approximately 98% of mouse skeletal muscle actin mRNA was determined from cDNA clones isolated from a library of recombinants in…”
Get more information

Bridged Hemilabile Allylphosphonate Ligand:  Synthesis and Crystal Structure of a New Binuclear Rhodium Complex by Le Gall, Irène, Laurent, Pascale, Toupet, Loïc, Salaün, Jean-Yves, des Abbayes, Hervé

“…The reaction of 2 equiv of the allylphosphonate CH2CHCH2P(O)(OEt)2 with [Rh(Cl)(CO)2]2 results in the formation of a new binuclear rhodium complex with two…”
Get full text

Root Productivity in a Lowland Tropical Rain Forest in Mexico by Sánchez-Gallén, Irene, Alvarez-Sánchez, Javier

“…Fine root productivity was estimated in a lowland tropical rain forest at Los Tuxtlas (SE Mexico) and examined in relation to climatic factors. Two root…”
Get full text