Search Results - "Gall, Gwenaelle Le"

Structural and Functional Alterations in the Microbial Community and Immunological Consequences in a Mouse Model of Antibiotic-Induced Dysbiosis by Shi, Ying, Kellingray, Lee, Zhai, Qixiao, Gall, Gwenaelle Le, Narbad, Arjan, Zhao, Jianxin, Zhang, Hao, Chen, Wei

“…The aim of this study was to establish continuous therapeutic-dose ampicillin (CTDA)-induced dysbiosis in a mouse model, mimicking typical adult exposure, with…”
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Differential Influence of Soluble Dietary Fibres on Intestinal and Hepatic Carbohydrate Response by Pontifex, Matthew G, Mushtaq, Aleena, Le Gall, Gwenaëlle, Rodriguez-Ramiro, Ildefonso, Blokker, Britt Anne, Hoogteijling, Mara E M, Ricci, Matthew, Pellizzon, Michael, Vauzour, David, Müller, Michael

“…Refined foods are commonly depleted in certain bioactive components that are abundant in 'natural' (plant) foods. Identification and addition of these…”
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In Silico Analysis of the Small Molecule Content of Outer Membrane Vesicles Produced by Bacteroides thetaiotaomicron Indicates an Extensive Metabolic Link between Microbe and Host by Bryant, William A, Stentz, Régis, Le Gall, Gwenaelle, Sternberg, Michael J E, Carding, Simon R, Wilhelm, Thomas

“…The interactions between the gut microbiota and its host are of central importance to the health of the host. Outer membrane vesicles (OMVs) are produced…”
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Offspring Metabolomic Response to Maternal Protein Restriction in a Rat Model of Intrauterine Growth Restriction (IUGR) by Alexandre-Gouabau, Marie-Cécile, Courant, Frédérique, Le Gall, Gwénaëlle, Moyon, Thomas, Darmaun, Dominique, Parnet, Patricia, Coupé, Bérengère, Antignac, Jean-Philippe

“…Intrauterine growth restriction (IUGR), along with postnatal growth trajectory, is closely linked with metabolic diseases and obesity at adulthood. The present…”
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Lactobacillus plantarum-Mediated Regulation of Dietary Aluminum Induces Changes in the Human Gut Microbiota: an In Vitro Colonic Fermentation Study by Yu, Leilei, Duan, Hui, Kellingray, Lee, Cen, Shi, Tian, Fengwei, Zhao, Jianxin, Zhang, Hao, Gall, Gwénaëlle Le, Mayer, Melinda J, Zhai, Qixiao, Chen, Wei, Narbad, Arjan

“…The gut microbiota has been identified as a target of toxic metals and a potentially crucial mediator of the bioavailability and toxicity of these metals. In…”
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A Comparison of the ATP Generating Pathways Used by S. Typhimurium to Fuel Replication within Human and Murine Macrophage and Epithelial Cell Lines by Garcia-Gutierrez, Enriqueta, Chidlaw, Amanda C, Le Gall, Gwenaelle, Bowden, Steven D, Tedin, Karsten, Kelly, David J, Thompson, Arthur

“…The metabolism of S. Typhimurium within infected host cells plays a fundamental role in virulence since it enables intracellular proliferation and…”
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Selenium-Dependent Biogenesis of Formate Dehydrogenase in Campylobacter jejuni Is Controlled by the fdhTU Accessory Genes by Shaw, Frances L, Mulholland, Francis, Le Gall, Gwénaëlle, Porcelli, Ida, Hart, Dave J, Pearson, Bruce M, van Vliet, Arnoud H. M

“…The food-borne bacterial pathogen Campylobacter jejuni efficiently utilizes organic acids such as lactate and formate for energy production. Formate is rapidly…”
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Characterization and Content of Flavonoid Glycosides in Genetically Modified Tomato (Lycopersicon esculentum) Fruits by Le Gall, Gwénaëlle, DuPont, M. Susan, Mellon, Fred A., Davis, Adrienne L., Collins, Geoff J., Verhoeyen, Martine E., Colquhoun, Ian J.

“…There is a growing interest in producing food plants with increased amounts of flavonoids because of their potential health benefits. Tomatoes contain small…”
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Metabolomics of prolonged fasting in humans reveals new catabolic markers by Rubio-Aliaga, Isabel, de Roos, Baukje, Duthie, Susan J., Crosley, L. Katie, Mayer, Claus, Horgan, Graham, Colquhoun, Ian J., Le Gall, Gwénaëlle, Huber, Fritz, Kremer, Werner, Rychlik, Michael, Wopereis, Suzan, van Ommen, Ben, Schmidt, Gabriele, Heim, Carolin, Bouwman, Freek G., Mariman, Edwin C., Mulholland, Francis, Johnson, Ian T., Polley, Abigael C., Elliott, Ruan M., Daniel, Hannelore

“…Fasting is one of the simplest metabolic challenges that can be performed in humans. We here report for the first time a comprehensive analysis of the human…”
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Utilisation of mucin glycans by the human gut symbiont Ruminococcus gnavus is strain-dependent by Crost, Emmanuelle H, Tailford, Louise E, Le Gall, Gwenaelle, Fons, Michel, Henrissat, Bernard, Juge, Nathalie

“…Commensal bacteria often have an especially rich source of glycan-degrading enzymes which allow them to utilize undigested carbohydrates from the food or the…”
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Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia by Connell, Emily, Le Gall, Gwenaelle, Pontifex, Matthew G, Sami, Saber, Cryan, John F, Clarke, Gerard, Müller, Michael, Vauzour, David

“…Abstract A consequence of our progressively ageing global population is the increasing prevalence of worldwide age-related cognitive decline and dementia. In…”
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Mechanistic Insights Into the Cross-Feeding of Ruminococcus gnavus and Ruminococcus bromii on Host and Dietary Carbohydrates by Crost, Emmanuelle H, Le Gall, Gwenaelle, Laverde-Gomez, Jenny A, Mukhopadhya, Indrani, Flint, Harry J, Juge, Nathalie

“…Dietary and host glycans shape the composition of the human gut microbiota with keystone carbohydrate-degrading species playing a critical role in maintaining…”
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Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain by Parker, Aimée, Romano, Stefano, Ansorge, Rebecca, Aboelnour, Asmaa, Le Gall, Gwenaelle, Savva, George M, Pontifex, Matthew G, Telatin, Andrea, Baker, David, Jones, Emily, Vauzour, David, Rudder, Steven, Blackshaw, L Ashley, Jeffery, Glen, Carding, Simon R

“…Altered intestinal microbiota composition in later life is associated with inflammaging, declining tissue function, and increased susceptibility to…”
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Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients by D'Amato, Alfonsina, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Man, Angela L, Le Gall, Gwenaelle, Branca, Jacopo J V, Ghelardini, Carla, Amedei, Amedeo, Bertelli, Eugenio, Regoli, Mari, Pacini, Alessandra, Luciani, Giulia, Gallina, Pasquale, Altera, Annalisa, Narbad, Arjan, Gulisano, Massimo, Hoyles, Lesley, Vauzour, David, Nicoletti, Claudio

“…The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a…”
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Metabolomics of Fecal Extracts Detects Altered Metabolic Activity of Gut Microbiota in Ulcerative Colitis and Irritable Bowel Syndrome by Le Gall, Gwénaëlle, Noor, Samah O, Ridgway, Karyn, Scovell, Louise, Jamieson, Crawford, Johnson, Ian T, Colquhoun, Ian J, Kemsley, E. Kate, Narbad, Arjan

“…1H NMR spectroscopy of aqueous fecal extracts has been used to investigate differences in metabolic activity of gut microbiota in patients with ulcerative…”
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Anti‐Inflammatory Effects of Quercetin on High‐Glucose and Pro‐Inflammatory Cytokine Challenged Vascular Endothelial Cell Metabolism by Ozyel, Besim, Le Gall, Gwénaëlle, Needs, Paul W., Kroon, Paul A.

“…Scope Pro‐inflammatory stimuli such as hyperglycemia and cytokines have been shown to negatively affect endothelial cell functions. The aim of this study is to…”
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Microbial taxonomic and metabolic alterations during faecal microbiota transplantation to treat Clostridium difficile infection by Kellingray, Lee, Gall, Gwénaëlle Le, Defernez, Marianne, Beales, Ian L.P., Franslem-Elumogo, Ngozi, Narbad, Arjan

“…This study aimed to examine changes to the microbiota composition and metabolic profiles of seven patients with recurrent Clostridium difficile infection…”
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Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation by Tailford, Louise E., Owen, C. David, Walshaw, John, Crost, Emmanuelle H., Hardy-Goddard, Jemma, Le Gall, Gwenaelle, de Vos, Willem M., Taylor, Garry L., Juge, Nathalie

“…The gastrointestinal mucus layer is colonized by a dense community of microbes catabolizing dietary and host carbohydrates during their expansion in the gut…”
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Identification of Genes Required for Glucan Exopolysaccharide Production in Lactobacillus johnsonii Suggests a Novel Biosynthesis Mechanism by Mayer, Melinda J, D'Amato, Alfonsina, Colquhoun, Ian J, Le Gall, Gwénaëlle, Narbad, Arjan

“…FI9785 makes two capsular exopolysaccharides-a heteropolysaccharide (EPS2) encoded by the operon and a branched glucan homopolysaccharide (EPS1). The…”
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Gene and Metabolite Regulatory Network Analysis of Early Developing Fruit Tissues Highlights New Candidate Genes for the Control of Tomato Fruit Composition and Development by Mounet, Fabien, Moing, Annick, Garcia, Virginie, Petit, Johann, Maucourt, Michael, Deborde, Catherine, Bernillon, Stéphane, le Gall, Gwénaëlle, Colquhoun, Ian, Defernez, Marianne, Giraudel, Jean-Luc, Rolin, Dominique, Rothan, Christophe, Lemaire-Chamley, Martine

“…Variations in early fruit development and composition may have major impacts on the taste and the overall quality of ripe tomato (Solanum lycopersicum) fruit…”
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