Search Results - "Galjart, N."

Particle Filtering for Multiple Object Tracking in Dynamic Fluorescence Microscopy Images: Application to Microtubule Growth Analysis by Smal, I., Draegestein, K., Galjart, N., Niessen, W., Meijering, E.

“…Quantitative analysis of dynamic processes in living cells by means of fluorescence microscopy imaging requires tracking of hundreds of bright spots in noisy…”
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A plus-end raft to control microtubule dynamics and function by Galjart, Niels, Perez, Franck

“…Cells require a properly oriented and organised microtubule array to transmit positional information. Recent data have revealed a heterogeneous population of…”
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Multiple object tracking in molecular bioimaging by Rao-Blackwellized marginal particle filtering by Smal, I., Meijering, E., Draegestein, K., Galjart, N., Grigoriev, I., Akhmanova, A., van Royen, M.E., Houtsmuller, A.B., Niessen, W.

“…Time-lapse fluorescence microscopy imaging has rapidly evolved in the past decade and has opened new avenues for studying intracellular processes in vivo. Such…”
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CLIPs and CLASPs and cellular dynamics by Galjart, Niels

“…The dynamic properties of microtubules are regulated by plus-end tracking proteins (+TIPs), which associate with the distal ends of microtubules. Among the…”
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Characterisation of transcriptionally active and inactive chromatin domains in neurons by Akhmanova, A, Verkerk, T, Langeveld, A, Grosveld, F, Galjart, N

“…The tandemly organised ribosomal DNA (rDNA) repeats are transcribed by a dedicated RNA polymerase in a specialised nuclear compartment, the nucleolus. There…”
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Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function by GALJART, N. J, MORREAU, H, WILLEMSEN, R, GILLEMANS, N, BONTEN, E. J, D'AZZO, A

“…The protective protein was first discovered because of its deficiency in the metabolic storage disorder galactosialidosis. It associates with lysosomal…”
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Expression of cDNA encoding the human "protective protein" associated with lysosomal beta-galactosidase and neuraminidase: homology to yeast proteases by Galjart, N J, Gillemans, N, Harris, A, van der Horst, G T, Verheijen, F W, Galjaard, H, d'Azzo, A

“…The "protective protein" is a glycoprotein that associates with lysosomal beta-galactosidase and neuraminidase and is deficient in the autosomal recessive…”
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Alternative splicing of β-galactosidase mRNA generates the classic lysosomal enzyme and a β-galactosidase-related protein by Morreau, H, Galjart, N.J., Gillemans, N, Willemsen, R, van der Horst, G.T., d'Azzo, A

“…We have isolated two cDNAs encoding human lysosomal β-galactosidase, the enzyme deficient in GM1-gangliosidosis and Morquio B syndrome, and a…”
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P470Microtubule plus-end tracking protein complex: a novel pharmacological target for modulating Nav1.5 trafficking and function by Marchal, G A, Portero, V, Casini, S, Verkerk, A O, Galjart, N, Remme, C A

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Human lysosomal protective protein. Glycosylation, intracellular transport, and association with beta-galactosidase in the endoplasmic reticulum by Morreau, H, Galjart, N J, Willemsen, R, Gillemans, N, Zhou, X Y, d'Azzo, A

“…In lysosomes beta-galactosidase and neuraminidase acquire a stable and active conformation through their association with the protective protein. The latter is…”
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Sheltering behavior and locomotor activity in 11 genetically diverse common inbred mouse strains using home-cage monitoring by Loos, Maarten, Koopmans, Bastijn, Aarts, Emmeke, Maroteaux, Gregoire, van der Sluis, Sophie, Verhage, Matthijs, Smit, August B

“…Functional genetic analyses in mice rely on efficient and in-depth characterization of the behavioral spectrum. Automated home-cage observation can provide a…”
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The gene encoding human protective protein (PPGB) is on chromosome 20 by Wiegant, J, Galjart, N J, Raap, A K, d'Azzo, A

“…Normal lymphocyte prometaphase chromosome spreads were hybridized in situ using single- and double-color fluorescence techniques. The results obtained with…”
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Cathepsin A deficiency in galactosialidosis : Studies of patients and carriers in 16 families by KLEIJER, W. J, GEILEN, G. C, JANSE, H. C, VAN DIGGELEN, O. P, ZHOU, X. Y, GALJART, N. J, GALJAARD, H, D'AZZO, A

“…Deficiency of lysosomal protective protein/cathepsin A in humans is the primary cause of galactosialidosis, a lysosomal storage disease characterized by…”
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Zfp-37 is a member of the KRAB zinc finger gene family and is expressed in neurons of the developing and adult CNS by MAZARAKIS, N, MICHALOVICH, D, KARIS, A, GROSVELD, F, GALJART, N

“…The murine Zfp-37 gene encodes a protein with 12 zinc fingers at its C-terminus (Nelki et al., 1990, Nucleic Acids Res. 18: 3655; Burke and Wolgemuth, 1992,…”
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CTCF contributes in a critical way to spermatogenesis and male fertility by Hernández-Hernández, Abrahan, Lilienthal, Ingrid, Fukuda, Nanaho, Galjart, Niels, Höög, Christer

“…The CCCTC-binding factor (CTCF) is an architectural protein that governs chromatin organization and gene expression in somatic cells. Here, we show that CTCF…”
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Asymmetric CLASP-Dependent Nucleation of Noncentrosomal Microtubules at the trans-Golgi Network by Efimov, Andrey, Kharitonov, Alexey, Efimova, Nadia, Loncarek, Jadranka, Miller, Paul M., Andreyeva, Natalia, Gleeson, Paul, Galjart, Niels, Maia, Ana R.R., McLeod, Ian X., Yates, John R., Maiato, Helder, Khodjakov, Alexey, Akhmanova, Anna, Kaverina, Irina

“…Proper organization of microtubule arrays is essential for intracellular trafficking and cell motility. It is generally assumed that most if not all…”
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Identification and in Vitro Reconstitution of Lysosomal Neuraminidase from Human Placenta by van der Horst, G T J, Galjart, N J, d'Azzo, A, Galjaard, H, Verheijen, F W

“…Lysosomal neuraminidase from human placenta has been obtained in its active form by association of an inactive neuraminidase polypeptide with β-galactosidase…”
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CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex by Mimori-Kiyosue, Yuko, Grigoriev, Ilya, Lansbergen, Gideon, Sasaki, Hiroyuki, Matsui, Chiyuki, Severin, Fedor, Galjart, Niels, Grosveld, Frank, Vorobjev, Ivan, Tsukita, Shoichiro, Akhmanova, Anna

“…CLIP-associating protein (CLASP) 1 and CLASP2 are mammalian microtubule (MT) plus-end binding proteins, which associate with CLIP-170 and CLIP-115. Using RNA…”
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Mouse "protective protein". cDNA cloning, sequence comparison, and expression by Galjart, N J, Gillemans, N, Meijer, D, d'Azzo, A

“…The "protective protein" is the glycoprotein that forms a complex with the lysosomal enzymes beta-galactosidase and neuraminidase. Its deficiency in man leads…”
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Within-strain variation in behavior differs consistently between common inbred strains of mice by Loos, Maarten, Koopmans, Bastijn, Aarts, Emmeke, Maroteaux, Gregoire, van der Sluis, Sophie, Verhage, Matthijs, Smit, August B.

“…Genetic and environmental factors interact throughout life and give rise to individual differences, i.e., individuality. The diversifying effect of…”
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