Search Results - "Galhoz, Ana"
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Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development
Published in Nature communications (01-09-2024)“…The development of functional neurons is a complex orchestration of multiple signaling pathways controlling cell proliferation and differentiation. Because the…”
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The Oncology Biomarker Discovery framework reveals cetuximab and bevacizumab response patterns in metastatic colorectal cancer
Published in Nature communications (04-09-2023)“…Precision medicine has revolutionised cancer treatments; however, actionable biomarkers remain scarce. To address this, we develop the Oncology Biomarker…”
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A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates
Published in eLife (04-12-2020)“…High-throughput testing of drugs across molecular-characterised cell lines can identify candidate treatments and discover biomarkers. However, the cells'…”
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Multi‐omic landscaping of human midbrains identifies disease‐relevant molecular targets and pathways in advanced‐stage Parkinson's disease
Published in Clinical and translational medicine (01-01-2022)“…Background Parkinson's disease (PD) is the second most common neurodegenerative disorder whose prevalence is rapidly increasing worldwide. The molecular…”
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Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens
Published in Patterns (New York, N.Y.) (14-08-2020)“…High-throughput drug screens in cancer cell lines test compounds at low concentrations, thereby enabling the identification of drug-sensitivity biomarkers,…”
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Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany
Published in Emerging infectious diseases (01-03-2022)“…Hospital staff are at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease (COVID-19) pandemic…”
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Künstliche Intelligenz und maschinelles Lernen in der Diabetesforschung
Published in Diabetologe (01-12-2021)“…Zusammenfassung Hintergrund Diabetes mellitus entwickelt sich zu einem globalen Gesundheitsproblem, das eine Transformation der Forschung und der medizinischen…”
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