Search Results - "Galgoczi, Szilvia"

Chromosomal instability during neurogenesis in Huntington's disease by Ruzo, Albert, Croft, Gist F, Metzger, Jakob J, Galgoczi, Szilvia, Gerber, Lauren J, Pellegrini, Cecilia, Wang, Jr, Hanbin, Fenner, Maria, Tse, Stephanie, Marks, Adam, Nchako, Corbyn, Brivanlou, Ali H

“…Huntington's disease (HD) is a fatal neurodegenerative disease caused by expansion of CAG repeats in the Huntingtin gene ( ). Neither its pathogenic mechanisms…”
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Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models by Metzger, Jakob J., Pereda, Carlota, Adhikari, Arjun, Haremaki, Tomomi, Galgoczi, Szilvia, Siggia, Eric D., Brivanlou, Ali H., Etoc, Fred

“…Organoids are carrying the promise of modeling complex disease phenotypes and serving as a powerful basis for unbiased drug screens, potentially offering a…”
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Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects by Galgoczi, Szilvia, Ruzo, Albert, Markopoulos, Christian, Yoney, Anna, Phan-Everson, Tien, Li, Shu, Haremaki, Tomomi, Metzger, Jakob J., Etoc, Fred, Brivanlou, Ali H.

“…ABSTRACT Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG repeats in the huntingtin gene (HTT). Although HD…”
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