Search Results - "Galegov, G A"

ANTIHIV/AIDS DRUG 6HP: ANTIVIRAL ACTIVITY, PRE-CLINICAL STUDY. EFFICIENCY IN ADULT HIV-INFECTED PATIENTS by Galegov, G. A., Andronova, V. L.

“…The new domestic antiretroviral drug 6HP, which is ammonium-3’-azido-3’-deoxythymidine-5’-carbomoylphosphonate, shows a high level of anti-HIV activity in…”
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Antiviral effect of novel purine conjugate LAS-131 against Herpes simplex virus type 1 (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1) in vitro by Andronova, V. L., Galegov, G. A., Musiyak, V. V., Vozdvizhenskaya, O. A., Levit, G. L., Krasnov, V. P.

“…Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong…”
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INFLUENCE OF IMMUNOMODULATORY DRUG STIMFORTE ON THE EXPERIMENTAL HERPES VIRUS INFECTION IN COMBINATION WITH ACYCLOVIR AND ON HIV-INFECTION IN COMBINATION WITH RETROVIR by Maldov, D. G., Andronova, V. L., Kalnina, L. B., Ilyichev, A. V., Nosik, D. N., Galegov, G. A.

“…The combined action of the immunostimulatory drug Stimforte and the basic etiotropic drug acyclovir commonly used to treat herpes infections was studied using…”
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Influence of the immunomodulatory drug stimforte on the humoral immune response in the experimental herpes virus infection by Maldov, D. G., Andronova, V. L., Balakina, A. A., Ilyichev, A. V., Galegov, G. A.

“…In the study of the immunostimulation preparation Stimforte activity using the model of the experimental herpes virus infection BALB/c, mice has shown that…”
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Combined Effect of Basic Antiherpetic Drugs with a New Inhibitor of the Terminase Complex of Herpes Simplex Virus Type 1 in Vero Cell Cultures by Andronova, V. L., Galegov, G. A., Vozdvizhenskaya, O. A., Levit, G. L., Krasnov, V. P., Charushin, V. N.

“…Carriers of herpes simplex virus type 1 (HSV-1) account for more than 90% of the global population. Infection manifests itself in the formation of blisters and…”
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New nido-carborane-containing conjugates of purine: synthesis and antiviral activity by Gruzdev, D. A., Telegina, A. A., Ol’shevskaya, V. A., Andronova, V. L., Galegov, G. A., Zarubaev, V. V., Levit, G. L., Krasnov, V. P.

“…New purine derivatives containing a nido -carborane fragment were synthesized by nucleophilic substitution of chlorine atom in 6-chloropurine and…”
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Phosphazide (nikavir) is a highly effective drug for the treatment of HIV/AIDS infection by Galegov, George A

“…Federation Convincing evidence for high therapeutic activity and tolerability of Phosphazide in the treatment of HIV/AIDS-infection is given. Phosphazide is…”
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Mutations in the DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs by Korovina, A. N, Gus'kova, A. A, Skoblov, M. Yu, Andronova, V. L, Galegov, G. A, Kochetkov, S. N, Kukhanova, M. K, Skoblov, Yu. S

“…Primary structures of DNA polymerase (ul30) and thymidine kinase (ul23) genes from several herpes simplex virus type 1 (HSV-1) clinical isolates di ffering in…”
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Study of the Antiviral Activity of Adamantane-Containing Chemical Compounds by I. I. LYUBIMOV, E. I. ISAEVA, E. N. VETROVA, A. V. LAVROVA, N. M. GRETSKAYA, I. V. SERKOV, V. V. BEZUGLOV, G. A. GALEGOV

“…Influenza and coronavirus infections are especially dangerous due to being capable of causing pandemics and clinical complications in the nervous and…”
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The Mechanism of the Stimforte Effect on the Activation of Target Cell Defense against Viral Infection by Mal’dov, D. G., Deryabin, P. G., Grigoryan, S. S., Mishin, D. V., Andronova, V. L., Isaeva, E. I., Galegov, G. A., Ilichev, A. V.

“…Stimforte in a wide range of concentrations (15–225 µg/mL) totally inhibits the cytopathic activity of hepatitis C virus (HCV) in the Vero-V cell culture…”
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5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine as inhibitors of viral and bacterial growth by Alexandrova, L. A., Efremenkova, O. V., Andronova, V. L., Galegov, G. A., Solyev, P. N., Karpenko, I. L., Kochetkov, S. N.

“…A series of 5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine have been synthesized by the interaction of…”
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THE MECHANISM OF STIMFORTE ACTION ON HERPESVIRUS INFECTION by Maldov, D. G., Andronova, V. L., Grigorian, S. S., Isaeva, E. I., Balakina, A. A., Terentyev, A. A., Ilyichev, A. V., Galegov, G. A.

“…Increased protease activity and a significant amount of granzyme B were observed in in organs of mice infected with acute herpes simplex virus HSV-1 with the…”
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Analysis of Antiviral Properties of Hexoral In Vitro against Some Viruses that Cause Acute Respiratory Infections and Herpes by Deryabin, P. G., Galegov, G. A., Andronova, V. A., Botikov, A. G.

“…Antiviral properties of Hexoral (0.1% solution and 0.2% aerosol for local application) and its constituent hexetidine against viruses causing human respiratory…”
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The genome nucleotide sequence of herpes simplex virus 1 strain L2 by Skoblov, M. Yu, Lavrov, A. V., Bragin, A. G., Zubtsov, D. A., Andronova, V. L., Galegov, G. A., Skoblov, Yu. S.

“…The genome nucleotide sequence of the reference strain of herpes simplex virus type 1 was obtained using the technique of full size sequencing. For the virus…”
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Different effects of the immunostimulatory drug Stimforte on infections of hepatitis C virus and herpes simplex virus type 1 by Maldov, D. G., Andronova, V. L., Grigorian, S. S., Isaeva, E. I., Deryabin, P. G., Mishin, D. V., Balakina, A. A., Ilyichev, A. V., Terentyev, A. A., Galegov, G. A.

“…Stimforte, an immune response-stimulating preparation, is active with respect to hepatitis C virus (HCV) and herpes simplex virus type I (HSV-1). The effects…”
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Complex of the herpes simplex virus type 1 origin binding protein UL9 with DNA as a platform for the design of a new type of antiviral drugs by Bazhulina, N.P., Surovaya, A.N., Gursky, Y.G., Andronova, V.L., Moiseeva, E.D., Nikitin, А.M., Golovkin, M.V., Galegov, G.А., Grokhovsky, S.L., Gursky, G.V.

“…The herpes simplex virus type 1 origin-binding protein, OBP, is a DNA helicase encoded by the UL9 gene. The protein binds in a sequence-specific manner to the…”
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Study of Antiherpetic Efficiency of Phosphite of Acycloguanosine Ableto Over come the Barrier of Resistance to Acyclovir by Andronova, V L, Jasko, M V, Kukhanova, M K, Galegov, G A, Skoblov, Yr S, Kochetkov, S N

“…As has been shown previously, phosphite of acycloguanosine (Hp-ACG) exhibits equal efficacy against ACV-sensitive and ACV-resistant HSV-1 strains in cell…”
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Effect of dimeric netropsin analogue 15Lys-bis-Nt and acyclovir on the reproduction of herpes simplex virus type 1. The search for variants of herpes virus with drug resistance to 15Lys-bis-Nt and acyclovir by Andronova, V. L., Grokhovsky, S. L., Surovaya, A. N., Gursky, G. V., Galegov, G. A.

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The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza a virus resistant to rimantadine (Amantadine) in vitro and in vivo by Deryabin, P. G., Galegov, G. A., Konstantinova, I. D., Muzyka, I. S., Miroshnikov, A. I., L’vov, D. K.

“…This paper presents the results of experimental study of the combined anti-influenza action of ribavirin and ozeltamivir on the reproduction of several…”
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Research of suppression of the herpes simplex virus reproduction with drug resistance using a combination 15-Lys-bis-Nt with some antiherpetic drugs by Andronova, V L, Grokhovskiĭ, S L, Surovaia, A N, Deriabin, P G, Gurskiĭ, G V, Galegov, G A

“…The antiviral effect of combinations of netropsin derivative 15-Lys-bis-Nt with the known antiherpetic compounds, whose activity does not depend on viral TK…”
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