Search Results - "Galea, C A"
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1
Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes
Published in Molecular pharmacology (01-04-2009)“…Kv1.3 potassium channels maintain the membrane potential of effector memory (T(EM)) T cells that are important mediators of multiple sclerosis, type 1 diabetes…”
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2
Clathrin and synaptic vesicle endocytosis: studies at the squid giant synapse
Published in Biochemical Society transactions (01-02-2006)“…The role of clathrin-mediated endocytosis in SV (synaptic vesicle) recycling has been studied by combining molecular biology, physiology and electron…”
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3
Ryanodine receptor adaptation
Published in The Journal of general physiology (01-12-2000)“…In the heart, depolarization during the action potential activates voltage-dependent Ca2+ channels that mediate a small, localized Ca2+ influx (Ica). The…”
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4
Modification of the substrate specificity of porcine pepsin for the enzymatic production of bovine hide gelatin
Published in Protein science (01-10-2000)“…The substrate specificity of porcine pepsin has been altered by site-directed mutagenesis in an attempt to selectively cleave bovine hide collagen at only a…”
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5
Electron heating in 2-D: combining Fermi-Ulam acceleration and magnetic-moment non-adiabaticity in a mirror-configuration plasma
Published 27-04-2022“…We analyze a new mechanism for the creation and confinement of energetic electrons in a mirror-configuration plasma. A Fermi-Ulam-type process, driven by…”
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6
Differential Ca2+ and Sr2+ regulation of intracellular divalent cations release in ventricular myocytes
Published in Cell calcium (Edinburgh) (01-08-2004)“…The regulation of the Ca2+ -induced Ca2+ release (CICR) from intracellular stores is a critical step in the cardiac cycle. The inherent positive feedback of…”
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7
Association of Villin with Phosphatidylinositol 4,5-Bisphosphate Regulates the Actin Cytoskeleton
Published in The Journal of biological chemistry (23-01-2004)“…Villin, an epithelial cell actin-binding protein, severs actin in vitro and in vivo. Previous studies report that phosphatidylinositol 4,5-bisphosphate (PIP2)…”
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8
Thermodynamic characterization of interactions between p27(Kip1) and activated and non-activated Cdk2: intrinsically unstructured proteins as thermodynamic tethers
Published in Biochimica et biophysica acta (01-02-2006)“…The cyclin-dependent kinase inhibitor (CKI) p27Kip1 plays a critical role in cell cycle regulation by binding and inhibiting (or activating) various…”
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Role of Intrinsic Flexibility in Signal Transduction Mediated by the Cell Cycle Regulator, p27 super(K) super(i) super(p) super(1)
Published in Journal of molecular biology (22-02-2008)“…p27 super(K) super(i) super(p) super(1) (p27), which controls eukaryotic cell division through interactions with cyclin-dependent kinases (Cdks), integrates…”
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10
Pulsed local-field fluorescence microscopy: a new approach for measuring cellular signals in the beating heart
Published in Pflügers Archiv (01-03-2003)“…In cardiac research, single-cell experimental models have been extensively used to study the molecular mechanisms of intracellular Ca(2+) homeostasis. The…”
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11
Differential Ca super(2+) and Sr super(2+) regulation of intracellular divalent cations release in ventricular myocytes
Published in Cell calcium (Edinburgh) (01-08-2004)“…The regulation of the Ca super(2+)-induced Ca super(2+) release (CICR) from intracellular stores is a critical step in the cardiac cycle. The inherent positive…”
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