Search Results - "Galbán, Craig"
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Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-07-2016)“…The small conducting airways are the major site of airflow obstruction in chronic obstructive pulmonary disease and may precede emphysema development. We…”
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Superparamagnetic Iron Oxide Nanotheranostics for Targeted Cancer Cell Imaging and pH-Dependent Intracellular Drug Release
Published in Molecular pharmaceutics (06-12-2010)“…Studies were conducted to develop antibody- and fluorescence-labeled superparamagnetic iron oxide nanoparticle (SPIO) nanotheranostics for magnetic resonance…”
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Disease Progression Modeling in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-02-2020)“…The decades-long progression of chronic obstructive pulmonary disease (COPD) renders identifying different trajectories of disease progression challenging. To…”
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Multi-site clinical evaluation of DW-MRI as a treatment response metric for breast cancer patients undergoing neoadjuvant chemotherapy
Published in PloS one (27-03-2015)“…To evaluate diffusion weighted MRI (DW-MR) as a response metric for assessment of neoadjuvant chemotherapy (NAC) in patients with primary breast cancer using…”
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Imaging proteolytic activity in live cells and animal models
Published in PloS one (11-06-2013)“…In addition to their degradative role in protein turnover, proteases play a key role as positive or negative regulators of signal transduction pathways and…”
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CT-Based Commercial Software Applications: Improving Patient Care Through Accurate COPD Subtyping
Published in International journal of chronic obstructive pulmonary disease (2022)“…Chronic obstructive pulmonary disease (COPD) is heterogenous in its clinical manifestations and disease progression. Patients often have disease courses that…”
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Integrated multimodal imaging of dynamic bone-tumor alterations associated with metastatic prostate cancer
Published in PloS one (10-04-2015)“…Bone metastasis occurs for men with advanced prostate cancer which promotes osseous growth and destruction driven by alterations in osteoblast and osteoclast…”
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A diffusion tensor imaging analysis of gender differences in water diffusivity within human skeletal muscle
Published in NMR in biomedicine (01-12-2005)“…The diffusive properties of adjacent muscles at rest were evaluated in male (n = 12) and female (n = 12) subjects using diffusion tensor imaging (DTI). The…”
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Computed tomography–based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression
Published in Nature medicine (01-11-2012)“…Chronic obstructive pulmonary disease (COPD) is now known to be a heterogeneous disorder, hence the pressing need to develop imaging biomarkers to…”
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Diffusive sensitivity to muscle architecture: a magnetic resonance diffusion tensor imaging study of the human calf
Published in European journal of applied physiology (01-12-2004)“…The aim of this study was to examine the diffusive properties of adjacent muscles at rest, and to determine the relationship between diffusive and…”
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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
Published in The Journal of clinical investigation (01-02-2012)“…Pancreatic cancer is almost invariably associated with mutations in the KRAS gene, most commonly KRASG12D, that result in a dominant-active form of the KRAS…”
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Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting
Published in Biomaterials (01-03-2011)“…Abstract While successful magnetic tumor targeting of iron oxide nanoparticles has been achieved in a number of models, the rapid blood clearance of…”
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Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles
Published in Biomaterials (01-09-2011)“…Abstract Magnetic iron oxide nanoparticles (MNPs) have been studied to circumvent the limitations of status-quo brain tumor therapy and can be targeted by…”
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Metastatic pancreatic cancer is dependent on oncogenic Kras in mice
Published in PloS one (03-12-2012)“…Pancreatic cancer is one of the deadliest human malignancies, and its prognosis has not improved over the past 40 years. Mouse models that spontaneously…”
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Small airway imaging phenotypes in biomass- and tobacco smoke-exposed patients with COPD
Published in ERJ open research (01-04-2017)“…http://ow.ly/gXu730abpKu…”
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Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-09-2019)“…Evidence suggests damage to small airways is a key pathologic lesion in chronic obstructive pulmonary disease (COPD). Computed tomography densitometry has been…”
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Multi-system repeatability and reproducibility of apparent diffusion coefficient measurement using an ice-water phantom
Published in Journal of magnetic resonance imaging (01-05-2013)“…Purpose: To determine quantitative quality control procedures to evaluate technical variability in multi‐center measurements of the diffusion coefficient of…”
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Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer
Published in Science signaling (27-01-2015)“…Genomic amplification of the gene encoding and phosphorylation of the protein FADD (Fas-associated death domain) is associated with poor clinical outcome in…”
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Parametric Response Map As an Imaging Biomarker to Distinguish Progression From Pseudoprogression in High-Grade Glioma
Published in Journal of clinical oncology (01-05-2010)“…To assess whether a new method of quantifying therapy-associated hemodynamic alterations may help to distinguish pseudoprogression from true progression in…”
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